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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 2
1981 2
1982 9
1983 9
1984 11
1985 23
1986 51
1987 35
1988 71
1989 93
1990 59
1991 81
1992 54
1993 83
1994 55
1995 57
1996 80
1997 62
1998 63
1999 57
2000 39
2001 46
2002 73
2003 47
2004 65
2005 69
2006 62
2007 71
2008 68
2009 71
2010 60
2011 61
2012 78
2013 106
2014 80
2015 109
2016 119
2017 116
2018 89
2019 112
2020 120
2021 118
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2,578 results
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Page 1
Efficacy and safety of high-dose ampicillin/sulbactam vs. colistin as monotherapy for the treatment of multidrug resistant Acinetobacter baumannii ventilator-associated pneumonia.
Betrosian AP, Frantzeskaki F, Xanthaki A, Douzinas EE. Betrosian AP, et al. J Infect. 2008 Jun;56(6):432-6. doi: 10.1016/j.jinf.2008.04.002. Epub 2008 May 23. J Infect. 2008. PMID: 18501431 Clinical Trial.
OBJECTIVE: To compare the safety and efficacy of ampicillin/sulbactam (Amp/Sulb) and colistin (COL) in the treatment of multidrug resistant Acinetobacter baumannii ventilator-associated pneumonia (VAP). ...Adverse events were 39.6% (including 33% nephrotoxicity) for …
OBJECTIVE: To compare the safety and efficacy of ampicillin/sulbactam (Amp/Sulb) and colistin (COL) in the treatment of multid …
Ceftriaxone versus ampicillin/sulbactam for the treatment of aspiration-associated pneumonia in adults.
Hasegawa S, Shiraishi A, Yaegashi M, Hosokawa N, Morimoto K, Mori T. Hasegawa S, et al. J Comp Eff Res. 2019 Nov;8(15):1275-1284. doi: 10.2217/cer-2019-0041. Epub 2019 Nov 18. J Comp Eff Res. 2019. PMID: 31736321 Free article.
Aim: To compare hospital mortality in patients with aspiration-associated pneumonia treated with ceftriaxone (CTRX) and in those treated with ampicillin/sulbactam (ABPC/SBT). Methods: From a Japanese multicentre observational study cohort of patients with pneumonia, …
Aim: To compare hospital mortality in patients with aspiration-associated pneumonia treated with ceftriaxone (CTRX) and in those treated wit …
Concentrations of ampicillin and sulbactam in serum and in various compartments of the respiratory tract of patients.
Wildfeuer A, Rühle KH, Bölcskei PL, Springsklee M. Wildfeuer A, et al. Infection. 1994 Mar-Apr;22(2):149-51. doi: 10.1007/BF01739027. Infection. 1994. PMID: 8070929
After infusion of 2 g ampicillin and 1 g sulbactam the concentrations of these two beta-lactams were determined in serum and various compartments of the respiratory tract of 22 patients. About 30 min after the end of the infusion in 15 patients the mean serum concen …
After infusion of 2 g ampicillin and 1 g sulbactam the concentrations of these two beta-lactams were determined in serum and v …
Ampicillin-sulbactam: an update on the use of parenteral and oral forms in bacterial infections.
Betrosian AP, Douzinas EE. Betrosian AP, et al. Expert Opin Drug Metab Toxicol. 2009 Sep;5(9):1099-112. doi: 10.1517/17425250903145251. Expert Opin Drug Metab Toxicol. 2009. PMID: 19621991 Review.
Ampicillin-sulbactam has a wide range of antibacterial activity that includes Gram-positive and Gram-negative aerobic and anaerobic bacteria. ...The combination could be considered particularly active against Acinetobacter baumannii infections due to the intrinsic a
Ampicillin-sulbactam has a wide range of antibacterial activity that includes Gram-positive and Gram-negative aerobic and anae
Pharmacokinetics of sulbactam and ampicillin in mice and in dogs.
Liu CX, Wang JR, Lu YL. Liu CX, et al. Yao Xue Xue Bao. 1990;25(6):406-11. Yao Xue Xue Bao. 1990. PMID: 2284964
Sulbactam is a new beta-lactamase inhibitor. The pharmacokinetic characteristics of sulbactam was similar to ampicillin after a single intravenous injection of 200 mg/kg in mice with a half-life of approximately 50 min. ...The Vc and Vd suggest that they are
Sulbactam is a new beta-lactamase inhibitor. The pharmacokinetic characteristics of sulbactam was similar to ampicillin
Rational antibiotic therapy and the position of ampicillin/sulbactam.
Lode HM. Lode HM. Int J Antimicrob Agents. 2008 Jul;32(1):10-28. doi: 10.1016/j.ijantimicag.2008.02.004. Epub 2008 Jun 6. Int J Antimicrob Agents. 2008. PMID: 18539004 Review.
In the current context of increasing antimicrobial resistance, it is important to use antibiotics rationally and to re-assess regularly the clinical usefulness of commonly used agents. This review focuses on the efficacy of the beta-lactam ampicillin co-administered with t …
In the current context of increasing antimicrobial resistance, it is important to use antibiotics rationally and to re-assess regularly the …
Effects of ampicillin/sulbactam and enrofloxacin on the blood pressure of isoflurane anesthetized dogs.
Moorer JD, Towle-Millard HA, Gross ME, Payton ME. Moorer JD, et al. J Am Anim Hosp Assoc. 2013 Sep-Oct;49(5):293-300. doi: 10.5326/JAAHA-MS-5899. Epub 2013 Jul 16. J Am Anim Hosp Assoc. 2013. PMID: 23861268 Clinical Trial.
A blinded, prospective, randomized crossover study was performed to determine the effects of ampicillin Na/sulbactam Na and enrofloxacin on the blood pressure (BP) of healthy anesthetized dogs. ...There was no significant change in the arterial pressure values over …
A blinded, prospective, randomized crossover study was performed to determine the effects of ampicillin Na/sulbactam Na and en …
Ampicillin/Sulbactam Treatment Modulates NMDA Receptor NR2B Subunit and Attenuates Neuroinflammation and Alcohol Intake in Male High Alcohol Drinking Rats.
Alasmari F, Alhaddad H, Wong W, Bell RL, Sari Y. Alasmari F, et al. Biomolecules. 2020 Jul 10;10(7):1030. doi: 10.3390/biom10071030. Biomolecules. 2020. PMID: 32664441 Free PMC article.
However, the effect of beta-lactam antibiotics on neuroinflammation in animals chronically exposed to ethanol has not been fully investigated. In this study, we evaluated the effects of ampicillin/sulbactam (AMP/SUL, 100 and 200 mg/kg, i.p.) on ethanol consumption i …
However, the effect of beta-lactam antibiotics on neuroinflammation in animals chronically exposed to ethanol has not been fully investigate …
Use of ampicillin/sulbactam and sultamicillin in pediatric infections: a re-evaluation.
Dajani A. Dajani A. J Int Med Res. 2001 Jul-Aug;29(4):257-69. doi: 10.1177/147323000102900401. J Int Med Res. 2001. PMID: 11675898 Free article. Review.
Ampicillin/sulbactam is an effective solution to the emergence of beta-lactamase-mediated resistance among common pediatric pathogens, and is a widely recognized treatment option for a variety of pediatric infections. ...Sultamicillin has an excellent tolerability p
Ampicillin/sulbactam is an effective solution to the emergence of beta-lactamase-mediated resistance among common pediatric pa
Pharmacokinetics of Prophylactic Ampicillin-Sulbactam and Dosing Optimization in Patients Undergoing Cardiovascular Surgery with Cardiopulmonary Bypass.
Yokoyama Y, Matsumoto K, Ikawa K, Watanabe E, Yamamoto H, Imoto Y, Morikawa N, Takeda Y. Yokoyama Y, et al. Biol Pharm Bull. 2015;38(11):1817-21. doi: 10.1248/bpb.b15-00334. Biol Pharm Bull. 2015. PMID: 26521833 Free article.
The total plasma concentrations of ampicillin were monitored in 8 patients after ampicillin (1 g)-sulbactam (0.5 g) administration via initial intravenous infusion and subsequent CPB priming. ...When ampicillin (1 g)-sulbactam (0.5 g) was intrav …
The total plasma concentrations of ampicillin were monitored in 8 patients after ampicillin (1 g)-sulbactam (0.5 g) adm …
2,578 results