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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 2
1981 2
1982 9
1983 9
1984 11
1985 23
1986 51
1987 35
1988 71
1989 93
1990 59
1991 81
1992 54
1993 83
1994 55
1995 57
1996 80
1997 62
1998 63
1999 57
2000 39
2001 46
2002 73
2003 47
2004 65
2005 69
2006 62
2007 71
2008 68
2009 71
2010 60
2011 61
2012 78
2013 106
2014 80
2015 109
2016 119
2017 116
2018 90
2019 113
2020 118
2021 141
2022 157
2023 172
2024 156
2025 196
2026 127

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3,321 results

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Page 1
Ampicillin-sulbactam against Acinetobacter baumannii infections: pharmacokinetic/pharmacodynamic appraisal of current susceptibility breakpoints and dosing recommendations.
Abouelhassan Y, Kuti JL, Nicolau DP, Abdelraouf K. Abouelhassan Y, et al. J Antimicrob Chemother. 2024 Sep 3;79(9):2227-2236. doi: 10.1093/jac/dkae218. J Antimicrob Chemother. 2024. PMID: 39031073 Free article.
Herein, we report a comprehensive PK/PD analysis of ampicillin-sulbactam against A. baumannii pneumonia. METHODS: Twenty-one A. baumannii clinical isolates were tested in the neutropenic murine pneumonia model. For dose-ranging studies, groups of mice were administe …
Herein, we report a comprehensive PK/PD analysis of ampicillin-sulbactam against A. baumannii pneumonia. METHODS: Twenty-one A …
Ampicillin-sulbactam versus third-generation cephalosporins in aspiration Pneumonia: A nationwide retrospective cohort study.
Taniguchi J, Aso S, Matsui H, Fushimi K, Yasunaga H. Taniguchi J, et al. Respir Med. 2025 Oct;247:108276. doi: 10.1016/j.rmed.2025.108276. Epub 2025 Jul 25. Respir Med. 2025. PMID: 40716681 Free article.
BACKGROUND: This study aims to evaluate the clinical outcomes of ampicillin-sulbactam versus third-generation cephalosporins (e.g., ceftriaxone or cefotaxime) in managing aspiration pneumonia. ...The mean treatment duration was 8.5 days (standard deviation [SD] 4.3) …
BACKGROUND: This study aims to evaluate the clinical outcomes of ampicillin-sulbactam versus third-generation cephalosporins ( …
Ampicillin-sulbactam.
Dajani AS. Dajani AS. Pediatr Ann. 1993 Mar;22(3):197-200. doi: 10.3928/0090-4481-19930301-10. Pediatr Ann. 1993. PMID: 8464651 No abstract available.
Pharmacokinetics of Ampicillin-Sulbactam in Azotemic and Non-Azotemic Dogs.
Wang Z, Shropshire S, Gustafson D, Fedotova S, Diaz A, Chornarm N, Daniels JB, Quimby J, Zersen KM. Wang Z, et al. J Vet Pharmacol Ther. 2025 Jul;48(4):241-249. doi: 10.1111/jvp.13506. Epub 2025 Mar 12. J Vet Pharmacol Ther. 2025. PMID: 40072220
Previous research has shown that azotemic dogs have a lower clearance and higher drug plasma concentrations of ampicillin compared to healthy dogs. The objective of this study was to determine the pharmacokinetics of ampicillin-sulbactam after multiple intrav …
Previous research has shown that azotemic dogs have a lower clearance and higher drug plasma concentrations of ampicillin compared to …
Population Pharmacokinetics and Dosing Simulations of Ampicillin and Sulbactam in Hospitalised Adult Patients.
Setiawan E, Cotta MO, Abdul-Aziz MH, Widjanarko D, Sosilya H, Lukas DL, Wallis SC, Parker S, Roberts JA. Setiawan E, et al. Clin Pharmacokinet. 2023 Apr;62(4):573-586. doi: 10.1007/s40262-023-01219-5. Epub 2023 Feb 28. Clin Pharmacokinet. 2023. PMID: 36853585 Free PMC article.
METHODS: Serial blood samples were collected from 16 adult patients receiving intravenous ampicillin-sulbactam in general wards. Total ampicillin and sulbactam concentrations were measured by chromatographic assay and pharmacokinetic parameters were es …
METHODS: Serial blood samples were collected from 16 adult patients receiving intravenous ampicillin-sulbactam in general ward …
Use of ampicillin/sulbactam and sultamicillin in pediatric infections: a re-evaluation.
Dajani A. Dajani A. J Int Med Res. 2001 Jul-Aug;29(4):257-69. doi: 10.1177/147323000102900401. J Int Med Res. 2001. PMID: 11675898 Free article. Review.
Ampicillin/sulbactam is an effective solution to the emergence of beta-lactamase-mediated resistance among common pediatric pathogens, and is a widely recognized treatment option for a variety of pediatric infections. ...Sultamicillin has an excellent tolerability p …
Ampicillin/sulbactam is an effective solution to the emergence of beta-lactamase-mediated resistance among common pediatric pa …
Sulbactam/ampicillin. A review of its antibacterial activity, pharmacokinetic properties, and therapeutic use.
Campoli-Richards DM, Brogden RN. Campoli-Richards DM, et al. Drugs. 1987 Jun;33(6):577-609. doi: 10.2165/00003495-198733060-00003. Drugs. 1987. PMID: 3038500 Review.
Sulbactam is poorly absorbed after oral administration and sulbactam/ampicillin is therefore administered parenterally, although another linked sulbactam-ampicillin compound, sultamicillin, has been developed which is well absorbed after oral ad …
Sulbactam is poorly absorbed after oral administration and sulbactam/ampicillin is therefore administered parenterally, …
Ampicillin-sulbactam: an update on the use of parenteral and oral forms in bacterial infections.
Betrosian AP, Douzinas EE. Betrosian AP, et al. Expert Opin Drug Metab Toxicol. 2009 Sep;5(9):1099-112. doi: 10.1517/17425250903145251. Expert Opin Drug Metab Toxicol. 2009. PMID: 19621991 Review.
Ampicillin-sulbactam has a wide range of antibacterial activity that includes Gram-positive and Gram-negative aerobic and anaerobic bacteria. ...The combination could be considered particularly active against Acinetobacter baumannii infections due to the intrinsic a …
Ampicillin-sulbactam has a wide range of antibacterial activity that includes Gram-positive and Gram-negative aerobic and anae …
Rational antibiotic therapy and the position of ampicillin/sulbactam.
Lode HM. Lode HM. Int J Antimicrob Agents. 2008 Jul;32(1):10-28. doi: 10.1016/j.ijantimicag.2008.02.004. Epub 2008 Jun 6. Int J Antimicrob Agents. 2008. PMID: 18539004 Review.
This review focuses on the efficacy of the beta-lactam ampicillin co-administered with the beta-lactamase inhibitor sulbactam, either parenterally (ampicillin/sulbactam) or orally (sultamicillin), for the treatment of bacterial infections. ...This is a …
This review focuses on the efficacy of the beta-lactam ampicillin co-administered with the beta-lactamase inhibitor sulbactam, …
3,321 results