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Year Number of Results
1990 3
1991 1
1995 1
1997 1
2007 4
2008 11
2009 15
2010 22
2011 27
2012 32
2013 26
2014 32
2015 38
2016 29
2017 23
2018 22
2019 22
2020 20
2021 3
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290 results
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Page 1
A Review of Asenapine in the Treatment of Bipolar Disorder.
Vieta E, Montes JM. Vieta E, et al. Clin Drug Investig. 2018 Feb;38(2):87-99. doi: 10.1007/s40261-017-0592-2. Clin Drug Investig. 2018. PMID: 29067671 Free PMC article. Review.
It is the antagonistic activity at the D(2) receptor that is likely responsible for the antimanic properties of asenapine. Clinical trials have demonstrated that asenapine mono- and add-on therapy is effective in the short- and long-term treatment of mania associate …
It is the antagonistic activity at the D(2) receptor that is likely responsible for the antimanic properties of asenapine. Clinical t …
Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia.
Leucht S, Crippa A, Siafis S, Patel MX, Orsini N, Davis JM. Leucht S, et al. Am J Psychiatry. 2020 Apr 1;177(4):342-353. doi: 10.1176/appi.ajp.2019.19010034. Epub 2019 Dec 16. Am J Psychiatry. 2020. PMID: 31838873
The 95% effective doses and the doses equivalent to 1 mg of oral risperidone, respectively, were as follows: amisulpride for patients with positive symptoms, 537 mg/day and 85.8 mg; aripiprazole, 11.5 mg/day and 1.8 mg; aripiprazole LAI (lauroxil), 463 mg every 4 weeks and 264 mg …
The 95% effective doses and the doses equivalent to 1 mg of oral risperidone, respectively, were as follows: amisulpride for patients with p …
Clinical Pharmacokinetics of Atypical Antipsychotics: An Update.
Mauri MC, Paletta S, Di Pace C, Reggiori A, Cirnigliaro G, Valli I, Altamura AC. Mauri MC, et al. Clin Pharmacokinet. 2018 Dec;57(12):1493-1528. doi: 10.1007/s40262-018-0664-3. Clin Pharmacokinet. 2018. PMID: 29915922 Review.
This review concentrates on the clinical pharmacokinetic data related to clozapine, risperidone, paliperidone, olanzapine, quetiapine, amisulpride, ziprasidone, aripiprazole, sertindole, asenapine, iloperidone, lurasidone, brexpiprazole and cariprazine and briefly consider …
This review concentrates on the clinical pharmacokinetic data related to clozapine, risperidone, paliperidone, olanzapine, quetiapine, amisu …
Asenapine.
Weber J, McCormack PL. Weber J, et al. CNS Drugs. 2009 Sep;23(9):781-92. doi: 10.2165/11200860-000000000-00000. CNS Drugs. 2009. PMID: 19689168 Review.
It is being developed for the treatment of schizophrenia and bipolar mania. In two randomized, controlled trials of asenapine monotherapy and in one randomized, controlled trial of adjunctive asenapine therapy in adult patients with bipolar I disorder, sublingual …
It is being developed for the treatment of schizophrenia and bipolar mania. In two randomized, controlled trials of asenapine monothe …
Clinically relevant interactions between newer antidepressants and second-generation antipsychotics.
Spina E, de Leon J. Spina E, et al. Expert Opin Drug Metab Toxicol. 2014 May;10(5):721-46. doi: 10.1517/17425255.2014.885504. Epub 2014 Feb 5. Expert Opin Drug Metab Toxicol. 2014. PMID: 24494611 Review.
Pharmacokinetic drug interaction (PK DI) and poorly understood pharmacodynamic (PD) drug interaction (PD DI) can occur between them. AREAS COVERED: This paper comprehensively reviews PD DI and PK DI studies. ...Possible beneficial PD DI effects occur a …
Pharmacokinetic drug interaction (PK DI) and poorly understood pharmacodynamic (PD) drug interaction (PD DI) can occur between …
Efficacy and Tolerability of Asenapine Compared with Olanzapine in Borderline Personality Disorder: An Open-Label Randomized Controlled Trial.
Bozzatello P, Rocca P, Uscinska M, Bellino S. Bozzatello P, et al. CNS Drugs. 2017 Sep;31(9):809-819. doi: 10.1007/s40263-017-0458-4. CNS Drugs. 2017. PMID: 28741044 Free article. Clinical Trial.
CONCLUSIONS: Asenapine and olanzapine were demonstrated to have a similar efficacy. While asenapine was found to be more efficacious than olanzapine in treating affective instability, olanzapine was superior to asenapine in treating paranoid ideation and diss …
CONCLUSIONS: Asenapine and olanzapine were demonstrated to have a similar efficacy. While asenapine was found to be more effic …
Asenapine for the Treatment of Psychotic Disorders.
Orr C, Deshpande S, Sawh S, Jones PM, Vasudev K. Orr C, et al. Can J Psychiatry. 2017 Feb;62(2):123-137. doi: 10.1177/0706743716661324. Epub 2016 Aug 6. Can J Psychiatry. 2017. PMID: 27481921 Free PMC article. Review.
No differences were found between asenapine and olanzapine in rates of discontinuation due to adverse drug reactions or lack of efficacy, but those taking asenapine had higher rates of withdrawal for any reason than those taking olanzapine. ...In comparison to place …
No differences were found between asenapine and olanzapine in rates of discontinuation due to adverse drug reactions or lack of effic …
Asenapine: A Review in Schizophrenia.
Plosker GL, Deeks ED. Plosker GL, et al. CNS Drugs. 2016 Jul;30(7):655-66. doi: 10.1007/s40263-016-0363-2. CNS Drugs. 2016. PMID: 27356921 Review.
This article reviews the pharmacology, clinical efficacy and tolerability profile of asenapine in the treatment of adults with schizophrenia. ...A meta-analysis of four short-term trials with asenapine (that also included a negative study and a failed trial) …
This article reviews the pharmacology, clinical efficacy and tolerability profile of asenapine in the treatment of adults with …
A History of the Pharmacological Treatment of Bipolar Disorder.
López-Muñoz F, Shen WW, D'Ocon P, Romero A, Álamo C. López-Muñoz F, et al. Int J Mol Sci. 2018 Jul 23;19(7):2143. doi: 10.3390/ijms19072143. Int J Mol Sci. 2018. PMID: 30041458 Free PMC article. Review.
In this paper, the authors review the history of the pharmacological treatment of bipolar disorder, from the first nonspecific sedative agents introduced in the 19th and early 20th century, such as solanaceae alkaloids, bromides and barbiturates, to John Cade's experiments …
In this paper, the authors review the history of the pharmacological treatment of bipolar disorder, from the first nonspecific sedative agen …
Asenapine: Pharmacological Aspects and Role in Psychiatric Disorders.
Reyad AA, Mishriky R. Reyad AA, et al. Psychiatr Danub. 2019 Jun;31(2):157-161. doi: 10.24869/psyd.2019.157. Psychiatr Danub. 2019. PMID: 31291219 Free article. Review.
Asenapine fulfils important requirements of efficacy and tolerability as an anti-psychotic. These findings should support psychiatrists and pharmacists in the care of their patients while on asenapine....
Asenapine fulfils important requirements of efficacy and tolerability as an anti-psychotic. These findings should support psychiatris
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