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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
2007 4
2008 6
2009 11
2010 19
2011 28
2012 32
2013 36
2014 37
2015 36
2016 25
2017 23
2018 26
2019 21
2020 18
2021 7
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290 results
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Page 1
A Review of Asenapine in the Treatment of Bipolar Disorder.
Vieta E, Montes JM. Vieta E, et al. Clin Drug Investig. 2018 Feb;38(2):87-99. doi: 10.1007/s40261-017-0592-2. Clin Drug Investig. 2018. PMID: 29067671 Free PMC article. Review.
It is the antagonistic activity at the D(2) receptor that is likely responsible for the antimanic properties of asenapine. Clinical trials have demonstrated that asenapine mono- and add-on therapy is effective in the short- and long-term treatment of mania associate …
It is the antagonistic activity at the D(2) receptor that is likely responsible for the antimanic properties of asenapine. Clinical t …
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder.
Yatham LN, Kennedy SH, Parikh SV, Schaffer A, Bond DJ, Frey BN, Sharma V, Goldstein BI, Rej S, Beaulieu S, Alda M, MacQueen G, Milev RV, Ravindran A, O'Donovan C, McIntosh D, Lam RW, Vazquez G, Kapczinski F, McIntyre RS, Kozicky J, Kanba S, Lafer B, Suppes T, Calabrese JR, Vieta E, Malhi G, Post RM, Berk M. Yatham LN, et al. Bipolar Disord. 2018 Mar;20(2):97-170. doi: 10.1111/bdi.12609. Epub 2018 Mar 14. Bipolar Disord. 2018. PMID: 29536616 Free PMC article.
Created by considering the impact of each treatment across all phases of illness, this hierarchy will further assist clinicians in making evidence-based treatment decisions. Lithium, quetiapine, divalproex, asenapine, aripiprazole, paliperidone, risperidone, and cariprazin …
Created by considering the impact of each treatment across all phases of illness, this hierarchy will further assist clinicians in making ev …
Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis.
Leucht S, Cipriani A, Spineli L, Mavridis D, Orey D, Richter F, Samara M, Barbui C, Engel RR, Geddes JR, Kissling W, Stapf MP, Lässig B, Salanti G, Davis JM. Leucht S, et al. Lancet. 2013 Sep 14;382(9896):951-62. doi: 10.1016/S0140-6736(13)60733-3. Epub 2013 Jun 27. Lancet. 2013. PMID: 23810019 Review.
METHODS: We did a Bayesian-framework, multiple-treatments meta-analysis (which uses both direct and indirect comparisons) of randomised controlled trials to compare 15 antipsychotic drugs and placebo in the acute treatment of schizophrenia. We searched the Cochrane Schizophrenia …
METHODS: We did a Bayesian-framework, multiple-treatments meta-analysis (which uses both direct and indirect comparisons) of randomised cont …
Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia.
Leucht S, Crippa A, Siafis S, Patel MX, Orsini N, Davis JM. Leucht S, et al. Am J Psychiatry. 2020 Apr 1;177(4):342-353. doi: 10.1176/appi.ajp.2019.19010034. Epub 2019 Dec 16. Am J Psychiatry. 2020. PMID: 31838873
The 95% effective doses and the doses equivalent to 1 mg of oral risperidone, respectively, were as follows: amisulpride for patients with positive symptoms, 537 mg/day and 85.8 mg; aripiprazole, 11.5 mg/day and 1.8 mg; aripiprazole LAI (lauroxil), 463 mg every 4 weeks and 264 mg …
The 95% effective doses and the doses equivalent to 1 mg of oral risperidone, respectively, were as follows: amisulpride for patients with p …
Clinical Pharmacokinetics of Atypical Antipsychotics: An Update.
Mauri MC, Paletta S, Di Pace C, Reggiori A, Cirnigliaro G, Valli I, Altamura AC. Mauri MC, et al. Clin Pharmacokinet. 2018 Dec;57(12):1493-1528. doi: 10.1007/s40262-018-0664-3. Clin Pharmacokinet. 2018. PMID: 29915922 Review.
Therapeutic drug monitoring studies have generally concentrated on controlling compliance and avoiding side effects by maintaining long-term exposure to minimally effective blood concentrations. The rationale for using therapeutic drug monitoring in relation to seco
Therapeutic drug monitoring studies have generally concentrated on controlling compliance and avoiding side effects by maintaining lo
Asenapine.
Weber J, McCormack PL. Weber J, et al. CNS Drugs. 2009 Sep;23(9):781-92. doi: 10.2165/11200860-000000000-00000. CNS Drugs. 2009. PMID: 19689168 Review.
It is being developed for the treatment of schizophrenia and bipolar mania. In two randomized, controlled trials of asenapine monotherapy and in one randomized, controlled trial of adjunctive asenapine therapy in adult patients with bipolar I disorder, sublingual …
It is being developed for the treatment of schizophrenia and bipolar mania. In two randomized, controlled trials of asenapine monothe …
Efficacy and Tolerability of Asenapine Compared with Olanzapine in Borderline Personality Disorder: An Open-Label Randomized Controlled Trial.
Bozzatello P, Rocca P, Uscinska M, Bellino S. Bozzatello P, et al. CNS Drugs. 2017 Sep;31(9):809-819. doi: 10.1007/s40263-017-0458-4. CNS Drugs. 2017. PMID: 28741044 Free article. Clinical Trial.
CONCLUSIONS: Asenapine and olanzapine were demonstrated to have a similar efficacy. While asenapine was found to be more efficacious than olanzapine in treating affective instability, olanzapine was superior to asenapine in treating paranoid ideation and diss …
CONCLUSIONS: Asenapine and olanzapine were demonstrated to have a similar efficacy. While asenapine was found to be more effic …
Asenapine for the Treatment of Psychotic Disorders.
Orr C, Deshpande S, Sawh S, Jones PM, Vasudev K. Orr C, et al. Can J Psychiatry. 2017 Feb;62(2):123-137. doi: 10.1177/0706743716661324. Epub 2016 Aug 6. Can J Psychiatry. 2017. PMID: 27481921 Free PMC article. Review.
No differences were found between asenapine and olanzapine in rates of discontinuation due to adverse drug reactions or lack of efficacy, but those taking asenapine had higher rates of withdrawal for any reason than those taking olanzapine. ...In comparison to place …
No differences were found between asenapine and olanzapine in rates of discontinuation due to adverse drug reactions or lack of effic …
Asenapine: A Review in Schizophrenia.
Plosker GL, Deeks ED. Plosker GL, et al. CNS Drugs. 2016 Jul;30(7):655-66. doi: 10.1007/s40263-016-0363-2. CNS Drugs. 2016. PMID: 27356921 Review.
A meta-analysis of four short-term trials with asenapine (that also included a negative study and a failed trial) also showed significant benefit with asenapine over placebo. ...However, in two trials in patients with persistent negative symptoms of schizophrenia, …
A meta-analysis of four short-term trials with asenapine (that also included a negative study and a failed trial) also showed signifi …
Safety, tolerability, and risks associated with first- and second-generation antipsychotics: a state-of-the-art clinical review.
Solmi M, Murru A, Pacchiarotti I, Undurraga J, Veronese N, Fornaro M, Stubbs B, Monaco F, Vieta E, Seeman MV, Correll CU, Carvalho AF. Solmi M, et al. Ther Clin Risk Manag. 2017 Jun 29;13:757-777. doi: 10.2147/TCRM.S117321. eCollection 2017. Ther Clin Risk Manag. 2017. PMID: 28721057 Free PMC article. Review.
Evidence, predominantly derived from systematic reviews, meta-analyses, and clinical trials of the drugs amisulpride, aripiprazole, asenapine, brexpiprazole, cariprazine, clozapine, iloperidone, lurasidone, olanzapine, paliperidone, quetiapine, risperidone, sertindole, zip …
Evidence, predominantly derived from systematic reviews, meta-analyses, and clinical trials of the drugs amisulpride, aripiprazole, asena
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