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Year Number of Results
1977 1
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204 results

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Page 1
Drugs for hypertension.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2024 May 27;66(1703):81-88. doi: 10.58347/tml.2024.1703a. Med Lett Drugs Ther. 2024. PMID: 38771738 Review. No abstract available.
Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). SHEP Cooperative Research Group.
[No authors listed] [No authors listed] JAMA. 1991 Jun 26;265(24):3255-64. JAMA. 1991. PMID: 2046107 Clinical Trial.
For step 1 of the trial, dose 1 was chlorthalidone, 12.5 mg/d, or matching placebo; dose 2 was 25 mg/d. For step 2, dose 1 was atenolol, 25 mg/d, or matching placebo; dose 2 was 50 mg/d. ...CONCLUSION: In persons aged 60 years and over with isolated systolic hyperte …
For step 1 of the trial, dose 1 was chlorthalidone, 12.5 mg/d, or matching placebo; dose 2 was 25 mg/d. For step 2, dose 1 was ate
Simultaneous quantification of atenolol and chlorthalidone in human plasma by ultra-performance liquid chromatography-tandem mass spectrometry.
Shah JV, Patel DP, Shah PA, Sanyal M, Shrivastav PS. Shah JV, et al. Biomed Chromatogr. 2016 Feb;30(2):208-16. doi: 10.1002/bmc.3537. Epub 2015 Jul 7. Biomed Chromatogr. 2016. PMID: 26096961
A simple, sensitive and reproducible ultra-performance liquid chromatography-tandem mass spectrometry method has been developed for the simultaneous determination of atenolol, a beta-adrenergic receptor-blocker and chlorthalidone, a monosulfonamyl diuretic in human …
A simple, sensitive and reproducible ultra-performance liquid chromatography-tandem mass spectrometry method has been developed for the simu …
Bioavailability in man of atenolol and chlorthalidone from a combination formulation.
McAinsh J, Bastain W, Young J, Harry JD. McAinsh J, et al. Biopharm Drug Dispos. 1981 Apr-Jun;2(2):147-56. doi: 10.1002/bdd.2510020207. Biopharm Drug Dispos. 1981. PMID: 7248478 Clinical Trial.
In this comparative bioavailability study in 12 healthy volunteers the blood level profiles and urinary recoveries of both atenolol and chlorthalidone were studied following the administration of the drug as a fixed combination ('Tenoretic'), as a free combination, …
In this comparative bioavailability study in 12 healthy volunteers the blood level profiles and urinary recoveries of both atenolol a …
Bioavailability in man of atenolol and chlorthalidone from a combination formulation.
McAinsh J, Holmes BH, Fitzsimons TJ, Young J. McAinsh J, et al. Biopharm Drug Dispos. 1986 May-Jun;7(3):223-31. doi: 10.1002/bdd.2510070303. Biopharm Drug Dispos. 1986. PMID: 3730522 Clinical Trial.
In this comparative bioavailability study in 12 healthy volunteers the blood level profiles and urinary recoveries of both atenolol and chlorthalidone were studied following the administration of the drugs as a fixed combination ('Tenoret 50'), as a free combination …
In this comparative bioavailability study in 12 healthy volunteers the blood level profiles and urinary recoveries of both atenolol a …
Pharmacokinetics of atenolol in hypertensive subjects with and without co-administration of chlorthalidone.
Riva E, Farina PL, Sega R, Tognoni G, Bastain W, McAinsh J. Riva E, et al. Eur J Clin Pharmacol. 1980 May;17(5):333-7. doi: 10.1007/BF00558445. Eur J Clin Pharmacol. 1980. PMID: 7418712
The pharmacokinetics of atenolol with and without the co-administration of chlorthalidone were studied in five hypertensive subjects. ...The atenolol elimination half-lives were 6.7 +/- 1.1 and 6.3 +/- 0.9 h, respectively, with and without chlorthalidone
The pharmacokinetics of atenolol with and without the co-administration of chlorthalidone were studied in five hypertensive su …
Atenolol and chlorthalidone in combination for hypertension.
Bateman DN, Dean CR, Mucklow JC, Bulpitt CJ, Dollery CT. Bateman DN, et al. Br J Clin Pharmacol. 1979 Apr;7(4):357-63. doi: 10.1111/j.1365-2125.1979.tb00946.x. Br J Clin Pharmacol. 1979. PMID: 375958 Free PMC article. Clinical Trial.
1 The hypotensive effect of single daily dosing with atenolol 100 mg and chlorthalidone 25 mg given alone or in combination has been assessed in a double-blind, crossover, placebo controlled trial in fifteen hypertensive patients. 2 Average lying blood pressures wer …
1 The hypotensive effect of single daily dosing with atenolol 100 mg and chlorthalidone 25 mg given alone or in combination ha …
Intraclass differences among antihypertensive drugs.
Feldman RD, Hussain Y, Kuyper LM, McAlister FA, Padwal RS, Tobe SW. Feldman RD, et al. Annu Rev Pharmacol Toxicol. 2015;55:333-52. doi: 10.1146/annurev-pharmtox-010814-124446. Epub 2014 Sep 22. Annu Rev Pharmacol Toxicol. 2015. PMID: 25251994 Review.
Based on a hierarchy-of-evidence approach, differences are apparent between hydrochlorothiazide and chlorthalidone based on evidence of moderate quality. Low-quality evidence suggests atenolol is less effective than other beta-blockers. ...
Based on a hierarchy-of-evidence approach, differences are apparent between hydrochlorothiazide and chlorthalidone based on evidence …
Drugs for hypertension.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2020 May 18;62(1598):73-80. Med Lett Drugs Ther. 2020. PMID: 32555118 No abstract available.
A Randomised Comparison of the Effects of Nebivolol and Atenolol with and without Chlorthalidone on the Sexual Function of Hypertensive Men.
Boydak B, Nalbantgil S, Fici F, Nalbantgil I, Zoghi M, Ozerkan F, Tengiz I, Ercan E, Yilmaz H, Yoket U, Onder R. Boydak B, et al. Clin Drug Investig. 2005;25(6):409-16. doi: 10.2165/00044011-200525060-00006. Clin Drug Investig. 2005. PMID: 17532681
After a 4-week placebo run-in period, patients were randomised to receive 12 weeks' therapy with nebivolol 5 mg/day (n = 43), atenolol 50 mg/day (n = 44), or atenolol 50 mg/day + chlorthalidone 12.5 mg/day (n = 44), according to a double-blind design. ...RESU …
After a 4-week placebo run-in period, patients were randomised to receive 12 weeks' therapy with nebivolol 5 mg/day (n = 43), atenolol
204 results