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Cardiovascular effects of Atenolol, scopolamine and their combination on healthy men in Finnish sauna baths.
Kukkonen-Harjula K, Oja P, Vuori I, Pasanen M, Lange K, Siitonen S, Metsä-Ketelä T, Vapaatalo H. Kukkonen-Harjula K, et al. Eur J Appl Physiol Occup Physiol. 1994;69(1):10-5. doi: 10.1007/BF00867920. Eur J Appl Physiol Occup Physiol. 1994. PMID: 7957149 Clinical Trial.
There were four bath sessions: one without a drug (control) and three with drug pretreatment (Atenolol 50 mg or Scopolamine 0.3 mg or their combination taken orally 2 h before the bath). ...The increase in heart rate per minute of heat exposure was significantly low …
There were four bath sessions: one without a drug (control) and three with drug pretreatment (Atenolol 50 mg or Scopolamine 0. …
Beta-adrenoceptor antagonists increase sinus arrhythmia, a vagotonic effect.
Bittiner SB, Smith SE. Bittiner SB, et al. Br J Clin Pharmacol. 1986 Dec;22(6):691-5. doi: 10.1111/j.1365-2125.1986.tb02959.x. Br J Clin Pharmacol. 1986. PMID: 2882771 Free PMC article. Clinical Trial.
Sinus arrhythmia was almost abolished by hyoscine butylbromide irrespective of the absence or presence and nature of the beta-adrenoceptor blocking drug. Atenolol and metoprolol alone prolonged the mean R-R interval and increased sinus arrhythmia. ...
Sinus arrhythmia was almost abolished by hyoscine butylbromide irrespective of the absence or presence and nature of the beta-adrenoc …