Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1962 1
1964 2
1965 12
1966 9
1967 12
1968 19
1969 17
1970 17
1971 15
1972 28
1973 22
1974 38
1975 34
1976 38
1977 41
1978 38
1979 64
1980 52
1981 36
1982 47
1983 61
1984 61
1985 55
1986 83
1987 65
1988 70
1989 57
1990 62
1991 59
1992 53
1993 37
1994 55
1995 66
1996 50
1997 56
1998 56
1999 51
2000 40
2001 47
2002 26
2003 32
2004 37
2005 35
2006 33
2007 34
2008 35
2009 35
2010 26
2011 24
2012 37
2013 30
2014 28
2015 31
2016 29
2017 27
2018 18
2019 17
2020 28
2021 30
2022 38
2023 34
2024 36
2025 31
2026 19

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

2,293 results

Results by year

Filters applied: . Clear all
Page 1
Effect of Low-Concentration Atropine Eyedrops vs Placebo on Myopia Incidence in Children: The LAMP2 Randomized Clinical Trial.
Yam JC, Zhang XJ, Zhang Y, Yip BHK, Tang F, Wong ES, Bui CHT, Kam KW, Ng MPH, Ko ST, Yip WWK, Young AL, Tham CC, Chen LJ, Pang CP. Yam JC, et al. JAMA. 2023 Feb 14;329(6):472-481. doi: 10.1001/jama.2022.24162. JAMA. 2023. PMID: 36786791 Free PMC article. Clinical Trial.
INTERVENTIONS: Participants were assigned at random to the 0.05% atropine (n = 160), 0.01% atropine (n = 159), and placebo (n = 155) groups and had eyedrops applied once nightly in both eyes over 2 years. ...Photophobia was the most common adverse event and was repo …
INTERVENTIONS: Participants were assigned at random to the 0.05% atropine (n = 160), 0.01% atropine (n = 159), and placebo (n …
Effect of atropine, orthokeratology and combined treatments for myopia control: a 2-year stratified randomised clinical trial.
Xu S, Li Z, Zhao W, Zheng B, Jiang J, Ye G, Feng Z, Long W, He L, He M, Hu Y, Yang X. Xu S, et al. Br J Ophthalmol. 2023 Nov 22;107(12):1812-1817. doi: 10.1136/bjo-2022-321272. Br J Ophthalmol. 2023. PMID: 36229177 Clinical Trial.
PURPOSE: To investigate the 2-year efficacy of atropine, orthokeratology (ortho-k) and combined treatment on myopia. To explore the factors influencing the efficacy. ...CONCLUSIONS: Atropine combined with ortho-k treatment can improve the efficacy of myopia control …
PURPOSE: To investigate the 2-year efficacy of atropine, orthokeratology (ortho-k) and combined treatment on myopia. To explore the f …
Two-Year Clinical Trial of the Low-Concentration Atropine for Myopia Progression (LAMP) Study: Phase 2 Report.
Yam JC, Li FF, Zhang X, Tang SM, Yip BHK, Kam KW, Ko ST, Young AL, Tham CC, Chen LJ, Pang CP. Yam JC, et al. Ophthalmology. 2020 Jul;127(7):910-919. doi: 10.1016/j.ophtha.2019.12.011. Epub 2019 Dec 21. Ophthalmology. 2020. PMID: 32019700 Clinical Trial.
Compared with the first year, the second-year efficacy of 0.05% and 0.025% atropine remained similar (P >0.1), but improved mildly in the 0.01% atropine group (P = 0.04). ...CONCLUSIONS: Over 2 years, the efficacy of 0.05% atropine observed was double that …
Compared with the first year, the second-year efficacy of 0.05% and 0.025% atropine remained similar (P >0.1), but improved mildly …
Efficacy and Safety of Different Atropine Regimens for the Treatment of Myopia in Children: Three-Year Results of the MOSAIC Randomized Clinical Trial.
Loughman J, Lingham G, Nkansah EK, Kobia-Acquah E, Flitcroft DI. Loughman J, et al. JAMA Ophthalmol. 2025 Feb 1;143(2):134-144. doi: 10.1001/jamaophthalmol.2024.5703. JAMA Ophthalmol. 2025. PMID: 39786755 Free PMC article. Clinical Trial.
IMPORTANCE: Additional data are required regarding atropine treatment regimens for control of myopia progression. OBJECTIVE: To investigate the efficacy and safety of different atropine regimens for myopia in children. ...Of 167 participants assigned to group 2, 133 …
IMPORTANCE: Additional data are required regarding atropine treatment regimens for control of myopia progression. OBJECTIVE: To inves …
Atropine for the treatment of childhood myopia: safety and efficacy of 0.5%, 0.1%, and 0.01% doses (Atropine for the Treatment of Myopia 2).
Chia A, Chua WH, Cheung YB, Wong WL, Lingham A, Fong A, Tan D. Chia A, et al. Ophthalmology. 2012 Feb;119(2):347-54. doi: 10.1016/j.ophtha.2011.07.031. Epub 2011 Oct 2. Ophthalmology. 2012. PMID: 21963266 Clinical Trial.
PURPOSE: Our previous study, Atropine for the Treatment of Myopia 1 (ATOM1), showed that atropine 1% eyedrops were effective in controlling myopic progression but with visual side effects resulting from cycloplegia and mydriasis. ...Allergic conjunctivitis and derma …
PURPOSE: Our previous study, Atropine for the Treatment of Myopia 1 (ATOM1), showed that atropine 1% eyedrops were effective i …
Atropine Versus Placebo for Neonatal Nonemergent Intubation: A Randomized Clinical Trial.
Afifi J, El-Naggar W, Hatfield T, Sandila N, Baier J, Narvey M. Afifi J, et al. J Pediatr. 2025 Nov;286:114719. doi: 10.1016/j.jpeds.2025.114719. Epub 2025 Jul 9. J Pediatr. 2025. PMID: 40645282 Clinical Trial.
OBJECTIVE: To compare the rates of severe bradycardia (<80/min for >10 seconds) between neonates who received atropine-fentanyl-succinylcholine (atropine/standard-of-care group) vs placebo-fentanyl-succinylcholine (placebo/intervention group) before orotrachea …
OBJECTIVE: To compare the rates of severe bradycardia (<80/min for >10 seconds) between neonates who received atropine-fentanyl …
Five-Year Clinical Trial on Atropine for the Treatment of Myopia 2: Myopia Control with Atropine 0.01% Eyedrops.
Chia A, Lu QS, Tan D. Chia A, et al. Ophthalmology. 2016 Feb;123(2):391-399. doi: 10.1016/j.ophtha.2015.07.004. Epub 2015 Aug 11. Ophthalmology. 2016. PMID: 26271839 Clinical Trial.
PARTICIPANTS: A total of 400 children originally randomized to receive atropine 0.5%, 0.1%, or 0.01% once daily in both eyes in a 2:2:1 ratio. METHODS: Children received atropine for 24 months (phase 1), after which medication was stopped for 12 months (phase 2). .. …
PARTICIPANTS: A total of 400 children originally randomized to receive atropine 0.5%, 0.1%, or 0.01% once daily in both eyes in a 2:2 …
A comparison of myopia control in European children and adolescents with defocus incorporated multiple segments (DIMS) spectacles, atropine, and combined DIMS/atropine.
Nucci P, Lembo A, Schiavetti I, Shah R, Edgar DF, Evans BJW. Nucci P, et al. PLoS One. 2023 Feb 16;18(2):e0281816. doi: 10.1371/journal.pone.0281816. eCollection 2023. PLoS One. 2023. PMID: 36795775 Free PMC article. Clinical Trial.
RESULTS: Of the 146 participants (mean age 10.3y 3.2), 53 received atropine, 30 DIMS spectacles, 31 atropine+DIMS, and 32 single vision control spectacles. ...For SER only, in pairwise comparisons at 12 months the atropine+DIMS group had significantly reduce …
RESULTS: Of the 146 participants (mean age 10.3y 3.2), 53 received atropine, 30 DIMS spectacles, 31 atropine+DIMS, and 32 sin …
Glycopyrrolate in children.
Warran P, Radford P, Manford ML. Warran P, et al. Br J Anaesth. 1981 Dec;53(12):1273-6. doi: 10.1093/bja/53.12.1273. Br J Anaesth. 1981. PMID: 7317246 Free article. Clinical Trial.
The effects of glycopyrrolate 10 microgram kg-1 i.v. given at induction of anaesthesia were compared with those of atropine 20 microgram kg-1 i.v. given at induction and oral atropine 30 microgram kg-1 given 90 min before operation. Antisialagogue effect, changes in …
The effects of glycopyrrolate 10 microgram kg-1 i.v. given at induction of anaesthesia were compared with those of atropine 20 microg …
Potential Choroidal Mechanisms Underlying Atropine's Antimyopic and Rebound Effects: A Mediation Analysis in a Randomized Clinical Trial.
Xu H, Ye L, Peng Y, Yu T, Li S, Weng S, Huang Y, Chen Y, Fan Y, Zou H, He J, Zhu J, Xu X. Xu H, et al. Invest Ophthalmol Vis Sci. 2023 Apr 3;64(4):13. doi: 10.1167/iovs.64.4.13. Invest Ophthalmol Vis Sci. 2023. PMID: 37043339 Free PMC article. Clinical Trial.
In total, 207 myopic children were assigned randomly to group A/B. Participants in group A received 1% atropine weekly (phase 1) and 0.01% atropine daily (phase 2) for 6 months each. Those in group B received 0.01% atropine daily for 1 year. ...The choroidal …
In total, 207 myopic children were assigned randomly to group A/B. Participants in group A received 1% atropine weekly (phase 1) and …
2,293 results