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Year Number of Results
1974 1
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Page 1
Acute effect of diphenoxylate with atropine (Lomotil) in patients with chronic diarrhea and fecal incontinence.
Harford WV, Krejs GJ, Santa Ana CA, Fordtran JS. Harford WV, et al. Gastroenterology. 1980 Mar;78(3):440-3. Gastroenterology. 1980. PMID: 7351282 Clinical Trial.
Fifteen patients with chronic diarrhea and fecal incontinence were admitted to a clinical research center and treated for 3 days with either placebo or diphenoxylate with atropine (Lomotil). The patients were then crossed over to the alternate medication. ...
Fifteen patients with chronic diarrhea and fecal incontinence were admitted to a clinical research center and treated for 3 days with either …
The efficacy of octreotide in the therapy of acute radiation-induced diarrhea: a randomized controlled study.
Yavuz MN, Yavuz AA, Aydin F, Can G, Kavgaci H. Yavuz MN, et al. Int J Radiat Oncol Biol Phys. 2002 Sep 1;54(1):195-202. doi: 10.1016/s0360-3016(02)02870-5. Int J Radiat Oncol Biol Phys. 2002. PMID: 12182992 Clinical Trial.
We performed a randomized study that compared octreotide acetate with diphenoxylate hydrochloride plus atropine sulfate, the drug commonly used as therapy for acute radiation-induced diarrhea (ARID). ...CONCLUSION: Octreotide seems to be more effective than conventi …
We performed a randomized study that compared octreotide acetate with diphenoxylate hydrochloride plus atropine sulfate, the d …
Pretreatment with diphenoxylate hydrochloride/atropine sulfate (Lomotil) does not decrease physiologic bowel FDG activity on PET/CT scans of the abdomen and pelvis.
Murphy R, Doerger KM, Nathan MA, Lowe VJ. Murphy R, et al. Mol Imaging Biol. 2009 Mar-Apr;11(2):114-7. doi: 10.1007/s11307-008-0178-8. Epub 2008 Nov 27. Mol Imaging Biol. 2009. PMID: 19037613 Clinical Trial.
We wished to determine if oral administration of the antimotility agent, Lomotil (5 mg diphenoxylate hydrochloride/0.05 mg atropine sulfate; G.D. Searle and Company, a division of Pfizer), prior to PET/CT scanning would reduce physiologic uptake of FDG by the small …
We wished to determine if oral administration of the antimotility agent, Lomotil (5 mg diphenoxylate hydrochloride/0.05 mg atropin …
Reduction of opioid-withdrawal symptoms with quetiapine.
Pinkofsky HB, Hahn AM, Campbell FA, Rueda J, Daley DC, Douaihy AB. Pinkofsky HB, et al. J Clin Psychiatry. 2005 Oct;66(10):1285-8. doi: 10.4088/jcp.v66n1011. J Clin Psychiatry. 2005. PMID: 16259542 Clinical Trial.
The treatment regimen generally included clonidine, hydroxyzine, trazodone, diphenoxylate/atropine, and sometimes chlordiazepoxide. Patients were also initially given eight 25-mg tablets of quetiapine and instructed to take 1 or 2 tablets every 4 hours as needed for …
The treatment regimen generally included clonidine, hydroxyzine, trazodone, diphenoxylate/atropine, and sometimes chlordiazepo …
Unfavorable effect of atropine-diphenoxylate (Lomotil) therapy in lincomycin-caused diarrhea.
Novak E, Lee JG, Seckman CE, Phillips JP, DiSanto AR. Novak E, et al. JAMA. 1976 Apr 5;235(14):1451-4. JAMA. 1976. PMID: 768533 Clinical Trial.
Gastrointestinal irritation was most prominent in subjects receiving lincomycin with atropine-diphenoxylate and lincomycin with APC plus codeine (P less than .05). ...The use of atropine-diphenoxylate or codeine in treating lincomycin-induced diarrhea …
Gastrointestinal irritation was most prominent in subjects receiving lincomycin with atropine-diphenoxylate and lincomycin wit …
Colestipol hydrochloride prophylaxis of diarrhea during pelvic radiotherapy.
Stryker JA, Chung CK, Layser JD. Stryker JA, et al. Int J Radiat Oncol Biol Phys. 1983 Feb;9(2):185-90. doi: 10.1016/0360-3016(83)90097-4. Int J Radiat Oncol Biol Phys. 1983. PMID: 6833021 Clinical Trial.
Thirty-three patients were randomized prior to pelvic radiotherapy to receive the bile acid-sequestering resin colestipol hydrochloride, 5 grams qid, during the entire time of their therapy or diphenoxylate hydrochloride and atropine sulfate 2.5-20 mg per day (contr …
Thirty-three patients were randomized prior to pelvic radiotherapy to receive the bile acid-sequestering resin colestipol hydrochloride, 5 g …
Antidiarrheal agents in the treatment of acute diarrhea in children.
Portnoy BL, DuPont HL, Pruitt D, Abdo JA, Rodriguez JT. Portnoy BL, et al. JAMA. 1976 Aug 16;236(7):844-6. JAMA. 1976. PMID: 781336 Clinical Trial.
Eighty patients, aged 3 to 11 years, were hospitalized and treated for two days with one of five agents: kaolin-pectin suspension concentrate (Kao-Con), kaolin suspension, pectin suspension, diphenoxylate-atropine liquid (Lomotil), or placebo. Although the patients …
Eighty patients, aged 3 to 11 years, were hospitalized and treated for two days with one of five agents: kaolin-pectin suspension concentrat …
Diphenoxylate therapy for psoriasis.
Lanier EW. Lanier EW. Arch Dermatol. 1985 Dec;121(12):1486. Arch Dermatol. 1985. PMID: 3904635 Clinical Trial. No abstract available.