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2020 2
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Effect of Sunscreen Application on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial.
Matta MK, Florian J, Zusterzeel R, Pilli NR, Patel V, Volpe DA, Yang Y, Oh L, Bashaw E, Zineh I, Sanabria C, Kemp S, Godfrey A, Adah S, Coelho S, Wang J, Furlong LA, Ganley C, Michele T, Strauss DG. Matta MK, et al. JAMA. 2020 Jan 21;323(3):256-267. doi: 10.1001/jama.2019.20747. JAMA. 2020. PMID: 31961417 Free PMC article. Clinical Trial.
OBJECTIVE: To assess the systemic absorption and pharmacokinetics of the 6 active ingredients (avobenzone, oxybenzone, octocrylene, homosalate, octisalate, and octinoxate) in 4 sunscreen products under single- and maximal-use conditions. ...MAIN OUTCOM …
OBJECTIVE: To assess the systemic absorption and pharmacokinetics of the 6 active ingredients (avobenzone, oxybenzone, octocrylene
Development of a novel rinse-off method for improved sunscreen exposure assessment.
Saxe JK, Dean S, Jones RL, Mullins LA, Reynertson KA. Saxe JK, et al. Integr Environ Assess Manag. 2021 Sep;17(5):961-966. doi: 10.1002/ieam.4451. Epub 2021 Jun 14. Integr Environ Assess Manag. 2021. PMID: 34002489 Free PMC article.
To improve the accuracy of exposure estimates and thereby develop more robust risk assessments, we measured the amount of the UVFs, avobenzone, homosalate, octisalate, octocrylene, and oxybenzone released to seawater from four sunscreen products (two l …
To improve the accuracy of exposure estimates and thereby develop more robust risk assessments, we measured the amount of the UVFs, avobe
Mechanistic Skin Modeling of Plasma Concentrations of Sunscreen Active Ingredients Following Facial Application.
Hamadeh A, Nash JF, Bialk H, Styczynski P, Troutman J, Edginton A. Hamadeh A, et al. J Pharm Sci. 2024 Mar;113(3):806-825. doi: 10.1016/j.xphs.2023.09.017. Epub 2023 Sep 26. J Pharm Sci. 2024. PMID: 37769994 Free article.
Building on earlier methods for predicting dermal disposition, a mechanistic model was developed to simulate plasma concentrations of seven organic sunscreen active ingredients: avobenzone, ensulizole, homosalate, octinoxate, octisalate, octocrylene, a …
Building on earlier methods for predicting dermal disposition, a mechanistic model was developed to simulate plasma concentrations of seven …
Occurrence of major organic UV filters in aquatic environments and their endocrine disruption potentials: A mini-review.
Kwon B, Choi K. Kwon B, et al. Integr Environ Assess Manag. 2021 Sep;17(5):940-950. doi: 10.1002/ieam.4449. Epub 2021 Jun 11. Integr Environ Assess Manag. 2021. PMID: 33991024 Review.
In the present study, we chose other major organic UV filters, such as avobenzone (AVB), homosalate (HS), octisalate (OS), and octocrylene (OC), and reviewed information on their use, environmental occurrences, and endocrine disruption effects, …
In the present study, we chose other major organic UV filters, such as avobenzone (AVB), homosalate (HS), octisalate (O …
In vitro metabolism of sunscreen compounds by liquid chromatography/high-resolution tandem mass spectrometry.
Guesmi A, Ohlund L, Sleno L. Guesmi A, et al. Rapid Commun Mass Spectrom. 2020 Apr 30;34(8):e8679. doi: 10.1002/rcm.8679. Rapid Commun Mass Spectrom. 2020. PMID: 31782973
RATIONALE: Exposure to UV light can induce adverse effects on human health, such as photo-aging, immunosuppression, and cancer. ...METHODS: Liquid chromatography coupled to high-resolution tandem mass spectrometry (LC/HRMS/MS) was employed to evaluate the oxidative …
RATIONALE: Exposure to UV light can induce adverse effects on human health, such as photo-aging, immunosuppression, and cancer …
Comparison between endocrine activity assessed using ToxCast/Tox21 database and human plasma concentration of sunscreen active ingredients/UV filters.
Onyango DO, Selman BG, Rose JL, Ellison CA, Nash JF. Onyango DO, et al. Toxicol Sci. 2023 Oct 30;196(1):25-37. doi: 10.1093/toxsci/kfad082. Toxicol Sci. 2023. PMID: 37561120 Free PMC article.
Concerns have been raised regarding the toxicity and potential endocrine disrupting (ED) effects of UV filters. The ToxCast/Tox21 program, that is, CompTox, is a high-throughput in vitro screening database of chemicals that identify adverse outcome pathways, key eve …
Concerns have been raised regarding the toxicity and potential endocrine disrupting (ED) effects of UV filters. The ToxCast/Tox21 pro …