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Page 1
Effect of Sunscreen Application on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial.
Matta MK, Florian J, Zusterzeel R, Pilli NR, Patel V, Volpe DA, Yang Y, Oh L, Bashaw E, Zineh I, Sanabria C, Kemp S, Godfrey A, Adah S, Coelho S, Wang J, Furlong LA, Ganley C, Michele T, Strauss DG. Matta MK, et al. JAMA. 2020 Jan 21;323(3):256-267. doi: 10.1001/jama.2019.20747. JAMA. 2020. PMID: 31961417 Free PMC article. Clinical Trial.
OBJECTIVE: To assess the systemic absorption and pharmacokinetics of the 6 active ingredients (avobenzone, oxybenzone, octocrylene, homosalate, octisalate, and octinoxate) in 4 sunscreen products under single- and maximal-use conditions. ...MAIN OUTCOMES AND …
OBJECTIVE: To assess the systemic absorption and pharmacokinetics of the 6 active ingredients (avobenzone, oxybenzone, octocrylene, h …
Sunscreens.
[No authors listed] [No authors listed] 2026 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2026 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 41730063 Free Books & Documents. Review.
Most organic chemical sunscreens are detectable in breastmilk, but the amounts that an infant would ingest are usually lower than current limits of concern.[1-5] Products containing octinoxate, enzacamene, and especially oxybenzone should probably be avoided during breastf …
Most organic chemical sunscreens are detectable in breastmilk, but the amounts that an infant would ingest are usually lower than current li …
Occurrence of major organic UV filters in aquatic environments and their endocrine disruption potentials: A mini-review.
Kwon B, Choi K. Kwon B, et al. Integr Environ Assess Manag. 2021 Sep;17(5):940-950. doi: 10.1002/ieam.4449. Epub 2021 Jun 11. Integr Environ Assess Manag. 2021. PMID: 33991024 Review.
In the present study, we chose other major organic UV filters, such as avobenzone (AVB), homosalate (HS), octisalate (OS), and octocrylene (OC), and reviewed information on their use, environmental occurrences, and endocrine disruption effects, available to date. .. …
In the present study, we chose other major organic UV filters, such as avobenzone (AVB), homosalate (HS), octisalate (OS), and …
In Vitro Testing of Sunscreens for Dermal Absorption: Method Comparison and Rank Order Correlation with In Vivo Absorption.
Yang Y, Ako-Adounvo AM, Wang J, Coelho SG, Adah SA, Matta MK, Strauss D, Michele TM, Wang J, Faustino PJ, O'Connor T, Ashraf M. Yang Y, et al. AAPS PharmSciTech. 2022 Apr 22;23(5):121. doi: 10.1208/s12249-022-02275-z. AAPS PharmSciTech. 2022. PMID: 35459978
The IVPT was used to evaluate dermal absorption of six UV filters (avobenzone, homosalate, octinoxate, octisalate, octocrylene, and oxybenzone) in commercial sunscreens. ...Rank orders of the cumulative in vitro skin permeation and the in vivo AUC were found …
The IVPT was used to evaluate dermal absorption of six UV filters (avobenzone, homosalate, octinoxate, octisalate, octo …
The dual challenge of FDA-evaluated non-GRASE UV filters: Photostability and systemic absorption - A path toward safer and more effective sunscreens.
Safian MT, Raja PB, Muniandy K, Karam Chand NS, Mohd Sahak MZ, Shaharudin S, Mohamad Ibrahim MN. Safian MT, et al. Int J Pharm. 2025 Jul 25;680:125790. doi: 10.1016/j.ijpharm.2025.125790. Epub 2025 May 30. Int J Pharm. 2025. PMID: 40451593 Review.
Category III Non-GRASE (Generally Recognized as Safe and Effective) UV filters (UVFs), such as avobenzone, octocrylene, oxybenzone, octinoxate, octisalate, and homosalate, face two significant challenges: photodegradation and systemic absorption. ...
Category III Non-GRASE (Generally Recognized as Safe and Effective) UV filters (UVFs), such as avobenzone, octocrylene, oxybenzone, …
Short-term and long-term effects of microplastics and organic UV-filters on the invertebrate model species Daphnia magna.
Svigruha R, Fodor I, Németh Z, Farkas A, Pirger Z, Ács A. Svigruha R, et al. Environ Sci Pollut Res Int. 2025 Feb;32(8):4841-4855. doi: 10.1007/s11356-025-36008-z. Epub 2025 Feb 1. Environ Sci Pollut Res Int. 2025. PMID: 39891809 Free PMC article.
In this study, neonates of the water flea (Daphnia magna) were exposed to polystyrene MPs (PS-MPs; 3 m; exposure concentration, 1.25 mg/L), a mixture of seven organic UV-filters (avobenzone, ethylhexyl triazone, homosalate, iscotrizinol, octinoxate, octisalate …
In this study, neonates of the water flea (Daphnia magna) were exposed to polystyrene MPs (PS-MPs; 3 m; exposure concentration, 1.25 mg/L), …
Mode of action approach supports a lack of carcinogenic potential of six organic UV filters.
Cohen SM, Boobis AR, Jacobson-Kram D, Schoeny R, Rosol TJ, Williams GM, Kaminski NE, Eichenbaum GM, Guengerich FP, Nash JF. Cohen SM, et al. Crit Rev Toxicol. 2025 Feb;55(2):248-284. doi: 10.1080/10408444.2025.2462642. Epub 2025 Apr 10. Crit Rev Toxicol. 2025. PMID: 40208192 Free article. Review.
Given these concerns with 2-year rodent carcinogenicity studies, we have developed and applied an alternative approach for supplementing existing data related to carcinogenic potential for six of the most commonly used UV filters in sunscreen products (i.e. avobenzone, ens …
Given these concerns with 2-year rodent carcinogenicity studies, we have developed and applied an alternative approach for supplementing exi …
Quantitation of Canadian organic ultraviolet filters using polarity switching and ultra-high performance liquid chromatography-tandem mass spectrometry.
Brown AK, Farenhorst A. Brown AK, et al. J Chromatogr A. 2023 Aug 16;1704:464132. doi: 10.1016/j.chroma.2023.464132. Epub 2023 Jun 4. J Chromatogr A. 2023. PMID: 37302251
This study developed a unified method to quantify eight UVFs (avobenzone, dioxybenzone, homosalate, octinoxate, octisalate, octocrylene, oxybenzone, and sulisobenzone) by solid phase extraction and ultra-high performance liquid chromatography-tandem mass spec …
This study developed a unified method to quantify eight UVFs (avobenzone, dioxybenzone, homosalate, octinoxate, octisalate …
Mechanistic Skin Modeling of Plasma Concentrations of Sunscreen Active Ingredients Following Facial Application.
Hamadeh A, Nash JF, Bialk H, Styczynski P, Troutman J, Edginton A. Hamadeh A, et al. J Pharm Sci. 2024 Mar;113(3):806-825. doi: 10.1016/j.xphs.2023.09.017. Epub 2023 Sep 26. J Pharm Sci. 2024. PMID: 37769994 Free article.
Building on earlier methods for predicting dermal disposition, a mechanistic model was developed to simulate plasma concentrations of seven organic sunscreen active ingredients: avobenzone, ensulizole, homosalate, octinoxate, octisalate, octocrylene, and oxyb …
Building on earlier methods for predicting dermal disposition, a mechanistic model was developed to simulate plasma concentrations of seven …
Comparison between endocrine activity assessed using ToxCast/Tox21 database and human plasma concentration of sunscreen active ingredients/UV filters.
Onyango DO, Selman BG, Rose JL, Ellison CA, Nash JF. Onyango DO, et al. Toxicol Sci. 2023 Oct 30;196(1):25-37. doi: 10.1093/toxsci/kfad082. Toxicol Sci. 2023. PMID: 37561120 Free PMC article.
The ToxCast/Tox21 program, that is, CompTox, is a high-throughput in vitro screening database of chemicals that identify adverse outcome pathways, key events, and ED potential of chemicals. Using the ToxCast/Tox21 database, octisalate, homosalate, octocrylene, oxybenzone, …
The ToxCast/Tox21 program, that is, CompTox, is a high-throughput in vitro screening database of chemicals that identify adverse outcome pat …
17 results