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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 1
1980 1
1981 9
1982 2
1983 2
1984 2
1985 3
1986 4
1987 8
1988 21
1989 24
1990 22
1991 28
1992 31
1993 29
1994 23
1995 22
1996 25
1997 36
1998 30
1999 19
2000 10
2001 13
2002 16
2003 18
2004 10
2005 8
2006 9
2007 10
2008 15
2009 15
2010 10
2011 12
2012 16
2013 11
2014 16
2015 12
2016 14
2017 9
2018 11
2019 14
2020 7
2021 16
2022 9
2023 8
2024 10
2025 11

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627 results

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Page 1
Second-generation antihistamines: a comparative review.
Slater JW, Zechnich AD, Haxby DG. Slater JW, et al. Drugs. 1999 Jan;57(1):31-47. doi: 10.2165/00003495-199957010-00004. Drugs. 1999. PMID: 9951950
This article evaluates second-generation antihistamines, including acrivastine, astemizole, azelastine, cetirizine, ebastine, fexofenadine, ketotifen, loratadine, mizolastine and terfenadine, for significant features that affect choice. ...
This article evaluates second-generation antihistamines, including acrivastine, astemizole, azelastine, cetirizine, ebastine, fexofen …
Intranasal Azelastine and Fluticasone as Combination Therapy for Allergic Rhinitis: Systematic Review and Meta-analysis.
Debbaneh PM, Bareiss AK, Wise SK, McCoul ED. Debbaneh PM, et al. Otolaryngol Head Neck Surg. 2019 Sep;161(3):412-418. doi: 10.1177/0194599819841883. Epub 2019 Apr 9. Otolaryngol Head Neck Surg. 2019. PMID: 30961435
OBJECTIVE: Combination therapy with intranasal azelastine and fluticasone propionate is an option for treatment of allergic rhinitis. This systematic review and meta-analysis examines existing literature to determine efficacy in treating allergic rhinitis compared to monot …
OBJECTIVE: Combination therapy with intranasal azelastine and fluticasone propionate is an option for treatment of allergic rhinitis. …
Azelastine hydrochloride: a review of pharmacology, pharmacokinetics, clinical efficacy and tolerability.
Bernstein JA. Bernstein JA. Curr Med Res Opin. 2007 Oct;23(10):2441-52. doi: 10.1185/030079907X226302. Curr Med Res Opin. 2007. PMID: 17723160 Review.
Azelastine has demonstrated a wide range of pharmacologic effects on chemical mediators of inflammation including leukotrienes, kinins, and platelet activating factor in vitro and in vivo. ...Clinical studies demonstrated that azelastine nasal spray can improve symp …
Azelastine has demonstrated a wide range of pharmacologic effects on chemical mediators of inflammation including leukotrienes, kinin …
Azelastine nasal spray: a review of pharmacology and clinical efficacy in allergic and nonallergic rhinitis.
Lieberman PL, Settipane RA. Lieberman PL, et al. Allergy Asthma Proc. 2003 Mar-Apr;24(2):95-105. Allergy Asthma Proc. 2003. PMID: 12776442 Review.
Azelastine hydrochloride is a pharmacologically distinct H1-receptor antagonist with a broad spectrum of antiallergic and anti-inflammatory activity. ...This article reviews the pharmacologic profile and clinical efficacy and safety of azelastine nasal spray....
Azelastine hydrochloride is a pharmacologically distinct H1-receptor antagonist with a broad spectrum of antiallergic and anti-inflam …
Antiviral Potential of Azelastine against Major Respiratory Viruses.
Fischhuber K, Bánki Z, Kimpel J, Kragl N, Rössler A, Bolze A, Muellauer B, Angerer J, Nagy G, Nagy E, Szijarto V. Fischhuber K, et al. Viruses. 2023 Nov 23;15(12):2300. doi: 10.3390/v15122300. Viruses. 2023. PMID: 38140540 Free PMC article.
We previously demonstrated that the antihistamine azelastine hydrochloride (azelastine-HCl) exhibited in vitro antiviral activity against SARS-CoV-2. ...Here, we evaluate the efficacy of azelastine-HCl against additional human coronaviruses, including the SAR …
We previously demonstrated that the antihistamine azelastine hydrochloride (azelastine-HCl) exhibited in vitro antiviral activ …
Azelastine inhibits viropexis of SARS-CoV-2 spike pseudovirus by binding to SARS-CoV-2 entry receptor ACE2.
Ge S, Lu J, Hou Y, Lv Y, Wang C, He H. Ge S, et al. Virology. 2021 Aug;560:110-115. doi: 10.1016/j.virol.2021.05.009. Epub 2021 May 25. Virology. 2021. PMID: 34052578 Free PMC article.
Here, we discovered antihistamine azelastine has an affinity to ACE2 by cell membrane chromatography (CMC); Then we determined the equilibrium dissociation constant (K(D)) of azelastine-ACE2 as (2.58 0.48) 10(-7) M by surface plasmon resonance (SPR). The results of …
Here, we discovered antihistamine azelastine has an affinity to ACE2 by cell membrane chromatography (CMC); Then we determined the eq …
Anti-chlamydial effects of azelastine hydrochloride and the impact of the histamine H1 receptor on chlamydial development.
Kuratli J, Leonard CA, Schoborg R, Borel N. Kuratli J, et al. J Med Microbiol. 2023 May;72(5). doi: 10.1099/jmm.0.001691. J Med Microbiol. 2023. PMID: 37195751
These effects were strongest when azelastine was added shortly after or with the infection. Azelastine effects were not alleviated by increased concentrations of culture medium nutrients. ...Thus, it appears likely that off-target mechanisms of azelastine may …
These effects were strongest when azelastine was added shortly after or with the infection. Azelastine effects were not allevi …
Future of allergic rhinitis management.
Linton S, Burrows AG, Hossenbaccus L, Ellis AK. Linton S, et al. Ann Allergy Asthma Immunol. 2021 Aug;127(2):183-190. doi: 10.1016/j.anai.2021.04.029. Epub 2021 May 7. Ann Allergy Asthma Immunol. 2021. PMID: 33971355 Review.
627 results