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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1981 1
1983 1
1985 2
1986 1
1987 8
1988 13
1989 15
1990 9
1991 10
1992 14
1993 18
1994 19
1995 16
1996 21
1997 28
1998 18
1999 15
2000 10
2001 15
2002 8
2003 16
2004 9
2005 7
2006 8
2007 10
2008 17
2009 15
2010 7
2011 10
2012 7
2013 12
2014 14
2015 10
2016 15
2017 10
2018 15
2019 10
2020 12
2021 12
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442 results
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Page 1
Anti-allergic drug azelastine suppresses colon tumorigenesis by directly targeting ARF1 to inhibit IQGAP1-ERK-Drp1-mediated mitochondrial fission.
Hu HF, Xu WW, Li YJ, He Y, Zhang WX, Liao L, Zhang QH, Han L, Yin XF, Zhao XX, Pan YL, Li B, He QY. Hu HF, et al. Theranostics. 2021 Jan 1;11(4):1828-1844. doi: 10.7150/thno.48698. eCollection 2021. Theranostics. 2021. PMID: 33408784 Free PMC article.
The target protein of azelastine was analyzed and confirmed by DARTS, WST-1, Biacore and tumor xenograft assays. ...This, in turn, inhibited mitochondrial fission and suppressed colon tumorigenesis by blocking IQGAP1-ERK signaling. Conclusions: This study provides the firs …
The target protein of azelastine was analyzed and confirmed by DARTS, WST-1, Biacore and tumor xenograft assays. ...This, in turn, in …
Current therapeutical strategies for allergic rhinitis.
Klimek L, Sperl A, Becker S, Mösges R, Tomazic PV. Klimek L, et al. Expert Opin Pharmacother. 2019 Jan;20(1):83-89. doi: 10.1080/14656566.2018.1543401. Epub 2018 Nov 15. Expert Opin Pharmacother. 2019. PMID: 30439290 Review.
The new formulation MP29-02 combines the nasal GCS fluticasone propionate with azelastine in one single spray and has achieved greater improvements than those under monotherapy with modern GCSs or antihistamines. ...
The new formulation MP29-02 combines the nasal GCS fluticasone propionate with azelastine in one single spray and has achieved greate …
OTC drugs for seasonal allergies.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2019 Apr 22;61(1570):57-60. Med Lett Drugs Ther. 2019. PMID: 31169808 No abstract available.
Second-generation antihistamines: a comparative review.
Slater JW, Zechnich AD, Haxby DG. Slater JW, et al. Drugs. 1999 Jan;57(1):31-47. doi: 10.2165/00003495-199957010-00004. Drugs. 1999. PMID: 9951950
This article evaluates second-generation antihistamines, including acrivastine, astemizole, azelastine, cetirizine, ebastine, fexofenadine, ketotifen, loratadine, mizolastine and terfenadine, for significant features that affect choice. ...Although current evidence does no …
This article evaluates second-generation antihistamines, including acrivastine, astemizole, azelastine, cetirizine, ebastine, fexofen …
Identification of SARS-CoV-2 entry inhibitors among already approved drugs.
Yang L, Pei RJ, Li H, Ma XN, Zhou Y, Zhu FH, He PL, Tang W, Zhang YC, Xiong J, Xiao SQ, Tong XK, Zhang B, Zuo JP. Yang L, et al. Acta Pharmacol Sin. 2021 Aug;42(8):1347-1353. doi: 10.1038/s41401-020-00556-6. Epub 2020 Oct 28. Acta Pharmacol Sin. 2021. PMID: 33116249 Free PMC article.
Antiviral tests using native SARS-CoV-2 virus in Vero E6 cells confirmed that 7 of these drugs (clemastine, amiodarone, trimeprazine, bosutinib, toremifene, flupenthixol, and azelastine) significantly inhibited SARS2 replication, reducing supernatant viral RNA load with a …
Antiviral tests using native SARS-CoV-2 virus in Vero E6 cells confirmed that 7 of these drugs (clemastine, amiodarone, trimeprazine, bosuti …
Azelastine nasal spray: a review of pharmacology and clinical efficacy in allergic and nonallergic rhinitis.
Lieberman PL, Settipane RA. Lieberman PL, et al. Allergy Asthma Proc. 2003 Mar-Apr;24(2):95-105. Allergy Asthma Proc. 2003. PMID: 12776442 Review.
Azelastine hydrochloride is a pharmacologically distinct H1-receptor antagonist with a broad spectrum of antiallergic and anti-inflammatory activity. ...This article reviews the pharmacologic profile and clinical efficacy and safety of azelastine nasal spray....
Azelastine hydrochloride is a pharmacologically distinct H1-receptor antagonist with a broad spectrum of antiallergic and anti-inflam
Identification of antiviral antihistamines for COVID-19 repurposing.
Reznikov LR, Norris MH, Vashisht R, Bluhm AP, Li D, Liao YJ, Brown A, Butte AJ, Ostrov DA. Reznikov LR, et al. Biochem Biophys Res Commun. 2021 Jan 29;538:173-179. doi: 10.1016/j.bbrc.2020.11.095. Epub 2020 Dec 3. Biochem Biophys Res Commun. 2021. PMID: 33309272 Free PMC article.
We found diphenhydramine, hydroxyzine and azelastine to exhibit direct antiviral activity against SARS-CoV-2 in vitro. ...Clinical studies are needed to measure the effectiveness of diphenhydramine, hydroxyzine and azelastine for disease prevention, for early interv …
We found diphenhydramine, hydroxyzine and azelastine to exhibit direct antiviral activity against SARS-CoV-2 in vitro. ...Clinical st …
For the Patient.
[No authors listed] [No authors listed] Allergy Asthma Proc. 2020 Jul 1;41(4):309. doi: 10.2500/aap.2020.41.200049. Allergy Asthma Proc. 2020. PMID: 32605703 No abstract available.
Azelastine hydrochloride: a review of pharmacology, pharmacokinetics, clinical efficacy and tolerability.
Bernstein JA. Bernstein JA. Curr Med Res Opin. 2007 Oct;23(10):2441-52. doi: 10.1185/030079907X226302. Curr Med Res Opin. 2007. PMID: 17723160 Review.
Azelastine has demonstrated a wide range of pharmacologic effects on chemical mediators of inflammation including leukotrienes, kinins, and platelet activating factor in vitro and in vivo. ...Clinical studies demonstrated that azelastine nasal spray can improve symp
Azelastine has demonstrated a wide range of pharmacologic effects on chemical mediators of inflammation including leukotrienes, kinin
442 results