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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1985 1
1986 1
1987 5
1988 6
1989 4
1990 3
1991 1
1992 5
1993 9
1994 11
1995 7
1996 13
1997 17
1998 11
1999 5
2000 6
2001 6
2002 1
2003 8
2004 1
2005 2
2006 4
2007 3
2008 10
2009 5
2010 3
2011 4
2012 5
2013 6
2014 2
2015 1
2016 2
2017 2
2018 5
2019 2
2020 1
2021 0
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173 results
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Page 1
Histamine and T helper cytokine-driven epithelial barrier dysfunction in allergic rhinitis.
Steelant B, Seys SF, Van Gerven L, Van Woensel M, Farré R, Wawrzyniak P, Kortekaas Krohn I, Bullens DM, Talavera K, Raap U, Boon L, Akdis CA, Boeckxstaens G, Ceuppens JL, Hellings PW. Steelant B, et al. J Allergy Clin Immunol. 2018 Mar;141(3):951-963.e8. doi: 10.1016/j.jaci.2017.08.039. Epub 2017 Oct 23. J Allergy Clin Immunol. 2018. PMID: 29074456 Free article. Clinical Trial.
RESULTS: Histamine as well as nasal secretions of AR but not idiopathic rhinitis patients rapidly decreased epithelial barrier integrity in vitro. Pretreatment with histamine receptor-1 antagonist, azelastine prevented the early effect of nasal secretions of AR patients on …
RESULTS: Histamine as well as nasal secretions of AR but not idiopathic rhinitis patients rapidly decreased epithelial barrier integrity in …
Safety of a novel intranasal formulation of azelastine hydrochloride and fluticasone propionate in children: A randomized clinical trial.
Berger W, Sher E, Gawchik S, Fineman S. Berger W, et al. Allergy Asthma Proc. 2018 Mar 1;39(2):110-116. doi: 10.2500/aap.2018.39.4116. Allergy Asthma Proc. 2018. PMID: 29490769 Free PMC article. Clinical Trial.
BACKGROUND: The safety of a novel intranasal formulation of azelastine hydrochloride (AZE) and fluticasone propionate (FP) has been established in adults and adolescents with allergic rhinitis but not in children <12 years old. ...
BACKGROUND: The safety of a novel intranasal formulation of azelastine hydrochloride (AZE) and fluticasone propionate (FP) has been e …
Azelastine tablets in the treatment of chronic idiopathic urticaria. Phase iii, randomised, double-blind, placebo and active controlled multicentric clinical trial.
Camarasa JM, Aliaga A, Fernández-Vozmediano JM, Fonseca E, Iglesias L, Tagarro I. Camarasa JM, et al. Skin Pharmacol Appl Skin Physiol. 2001 Mar-Apr;14(2):77-86. doi: 10.1159/000056337. Skin Pharmacol Appl Skin Physiol. 2001. PMID: 11316966 Clinical Trial.
This trial was designed to study the efficacy and tolerability of azelastine in controlling symptoms of chronic idiopathic urticaria, using ebastine as validation group. ...Global assessments of efficacy and tolerability performed by the investigators, also favoured aze
This trial was designed to study the efficacy and tolerability of azelastine in controlling symptoms of chronic idiopathic urticaria, …
Efficacy and safety of azelastine 0.15% nasal spray and azelastine 0.10% nasal spray in patients with seasonal allergic rhinitis.
Shah S, Berger W, Lumry W, La Force C, Wheeler W, Sacks H. Shah S, et al. Allergy Asthma Proc. 2009 Nov-Dec;30(6):628-33. doi: 10.2500/aap.2009.30.3296. Epub 2009 Nov 19. Allergy Asthma Proc. 2009. PMID: 19930788 Clinical Trial.
Onset of action with azelastine 0.15% was within 30 minutes. Bitter taste was the most common adverse event with both azelastine 0.15% and azelastine 0.10% (8.4% and 9.4% of patients, respectively). Somnolence was reported by 1.7% of patients treated with …
Onset of action with azelastine 0.15% was within 30 minutes. Bitter taste was the most common adverse event with both azelastine
Bioavailability and disposition of azelastine and fluticasone propionate when delivered by MP29-02, a novel aqueous nasal spray.
Derendorf H, Munzel U, Petzold U, Maus J, Mascher H, Hermann R, Bousquet J. Derendorf H, et al. Br J Clin Pharmacol. 2012 Jul;74(1):125-33. doi: 10.1111/j.1365-2125.2012.04222.x. Br J Clin Pharmacol. 2012. PMID: 22356350 Free PMC article. Clinical Trial.
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: The topical second generation anti-histamine azelastine hydrochloride (AZE) and the potent corticosteroid fluticasone propionate (FP) are well established first-line treatments in allergic rhinitis (AR). ...CONCLUSIONS: No interact …
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: The topical second generation anti-histamine azelastine hydrochloride (AZE) and the potent …
Open-label evaluation of azelastine nasal spray in patients with seasonal allergic rhinitis and nonallergic vasomotor rhinitis.
Lieberman P, Kaliner MA, Wheeler WJ. Lieberman P, et al. Curr Med Res Opin. 2005 Apr;21(4):611-8. doi: 10.1185/030079905X41408. Curr Med Res Opin. 2005. PMID: 15899111 Clinical Trial.
Patients who qualified for enrollment were given open-label azelastine nasal spray and instructed to administer 2 sprays per nostril twice daily for 2 weeks. ...CONCLUSIONS: Azelastine nasal spray was reported to control all rhinitis symptoms, including nasal conges …
Patients who qualified for enrollment were given open-label azelastine nasal spray and instructed to administer 2 sprays per nostril …
A clinical trial of Azelastine in recurrent aphthous ulceration, with an analysis of its actions on leukocytes.
Ueta E, Osaki T, Yoneda K, Yamamoto T, Kato I. Ueta E, et al. J Oral Pathol Med. 1994 Mar;23(3):123-9. doi: 10.1111/j.1600-0714.1994.tb01099.x. J Oral Pathol Med. 1994. PMID: 8021845 Clinical Trial.
Azelastine (azelastine hydrochloride) was orally administered to 43 patients with recurrent aphthous ulcers (RAU), and its clinical effects and in vitro influence on leukocytes were examined. ...These clinical and experimental results lead to the conclusion that imp
Azelastine (azelastine hydrochloride) was orally administered to 43 patients with recurrent aphthous ulcers (RAU), and its cli
A Pilot Study Investigating Clinical Responses and Biological Pathways of Azelastine/Fluticasone in Nonallergic Vasomotor Rhinitis before and after Cold Dry Air Provocation.
Singh U, Bernstein JA, Lorentz H, Sadoway T, Nelson V, Patel P, Salapatek AM. Singh U, et al. Int Arch Allergy Immunol. 2017;173(3):153-164. doi: 10.1159/000478698. Epub 2017 Aug 9. Int Arch Allergy Immunol. 2017. PMID: 28787742 Clinical Trial.
METHODS: To determine clinical responses and biological pathways in NAVMR subjects challenged to cold dry air (CDA) in an environmental exposure chamber (EEC) pre- and posttreatment with azelastine/fluticasone (AzeFlu), 30 NAVMR subjects, prescreened for CDA-induced sympto …
METHODS: To determine clinical responses and biological pathways in NAVMR subjects challenged to cold dry air (CDA) in an environmental expo …
[Clinical observation of nasal spray allergen blocker combined with antihistamines in treatment of allergic rhinitis children].
Wu XM, Feng YJ, Zeng CR, Wang MJ. Wu XM, et al. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Jan;34(1):60-63. doi: 10.13201/j.issn.1001-1781.2020.01.015. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020. PMID: 32086901 Clinical Trial. Chinese.
Method:Eighty-four children with mild-severe allergic rhinitis were randomly divided into observation group(42 cases) and control group(42 cases). Children in control group were treated with azelastine hydrochloride nasal spray, while children in observation group added wi …
Method:Eighty-four children with mild-severe allergic rhinitis were randomly divided into observation group(42 cases) and control group(42 c …
Azelastine reduces allergen-induced nasal response: a clinical and rhinomanometric assessment.
Lurie A, Saudubray F, Eychenne JL, Venot A, de Lauture D, Dessanges JF, Lockhart A, Strauch G. Lurie A, et al. Eur J Clin Pharmacol. 1992;42(2):213-6. doi: 10.1007/BF00278487. Eur J Clin Pharmacol. 1992. PMID: 1352247 Clinical Trial.
The effect of azelastine 2 mg b.d. p.o. for 10 days on grass pollen-induced nasal responses in 16 patients with grass pollen allergic rhinitis has been assessed. ...The visual analogue scores were similar before and after azelastine as well as before and after the p …
The effect of azelastine 2 mg b.d. p.o. for 10 days on grass pollen-induced nasal responses in 16 patients with grass pollen allergic …
173 results