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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1962 1
1963 1
1965 1
1971 1
1972 3
1973 4
1974 8
1975 17
1976 32
1977 50
1978 52
1979 44
1980 64
1981 67
1982 84
1983 61
1984 102
1985 128
1986 130
1987 136
1988 162
1989 183
1990 195
1991 211
1992 246
1993 273
1994 179
1995 210
1996 206
1997 188
1998 209
1999 239
2000 205
2001 209
2002 216
2003 243
2004 249
2005 228
2006 247
2007 271
2008 256
2009 235
2010 225
2011 266
2012 260
2013 242
2014 291
2015 279
2016 273
2017 283
2018 291
2019 240
2020 249
2021 230
2022 163
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8,486 results
Results by year
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Page 1
Intrathecal Baclofen Infusion for the Treatment of Movement Disorders.
Lake W, Shah H. Lake W, et al. Neurosurg Clin N Am. 2019 Apr;30(2):203-209. doi: 10.1016/j.nec.2018.12.002. Epub 2019 Feb 18. Neurosurg Clin N Am. 2019. PMID: 30898271 Review.
Intrathecal baclofen infusion is an accepted treatment for spasticity. Evidence also exists for the treatment of secondary generalized dystonia with intrathecal baclofen infusion. ...In some cases, practitioners encourage a trial dose of intrathecal baclofen
Intrathecal baclofen infusion is an accepted treatment for spasticity. Evidence also exists for the treatment of secondary generalize …
The GABAB Receptor-Structure, Ligand Binding and Drug Development.
Evenseth LSM, Gabrielsen M, Sylte I. Evenseth LSM, et al. Molecules. 2020 Jul 7;25(13):3093. doi: 10.3390/molecules25133093. Molecules. 2020. PMID: 32646032 Free PMC article. Review.
Despite extensive efforts, few compounds are known to target the receptor, and only the agonist baclofen is approved for clinical use. The receptor is a mandatory heterodimer of the GABA(B1) and GABA(B2) subunits, and each subunit is composed of an extracellular Venus Flyt …
Despite extensive efforts, few compounds are known to target the receptor, and only the agonist baclofen is approved for clinical use …
[Addiction].
Besson J, Khazaal Y, Tomei A, Grivel J, Zullino D. Besson J, et al. Rev Med Suisse. 2015 Jan 14;11(456-457):11-4. Rev Med Suisse. 2015. PMID: 25799644 French.
This year, the actuality about addiction is on psychopharmacology, in the controversy about the prescription of baclofene to reduce the craving for alcohol. More results from controlled studies are expected. ...This is the cause of a handicap in the social relationships. A …
This year, the actuality about addiction is on psychopharmacology, in the controversy about the prescription of baclofene to reduce t …
Classics in Chemical Neuroscience: Baclofen.
Kent CN, Park C, Lindsley CW. Kent CN, et al. ACS Chem Neurosci. 2020 Jun 17;11(12):1740-1755. doi: 10.1021/acschemneuro.0c00254. Epub 2020 Jun 3. ACS Chem Neurosci. 2020. PMID: 32436697 Review.
Baclofen, beta-(4-chlorophenyl)-gamma-aminobutyric acid, holds a unique position in neuroscience, remaining the only U.S. ...While intended to be a more brain penetrant, i.e, ability to cross the blood-brain barrier (BBB), version of GABA (gamma-aminobutyric acid) f
Baclofen, beta-(4-chlorophenyl)-gamma-aminobutyric acid, holds a unique position in neuroscience, remaining the only U.S. ...W
Systemic and intrathecal baclofen produce bladder antinociception in rats.
Ness TJ, Randich A, Su X, DeWitte C, Hildebrand K. Ness TJ, et al. BMC Urol. 2021 Oct 4;21(1):139. doi: 10.1186/s12894-021-00899-0. BMC Urol. 2021. PMID: 34607587 Free PMC article.
There were no differences in the magnitude of the analgesic effects of baclofen as a function of inflammation versus no inflammation treatments. ...Tolerance to a seven day continuous IT infusion of baclofen was not observed. CONCLUSIONS: These data provide support …
There were no differences in the magnitude of the analgesic effects of baclofen as a function of inflammation versus no inflammation …
Chirality counts?
Smith HS. Smith HS. Pain Physician. 2012 Jul-Aug;15(4):E355-7. Pain Physician. 2012. PMID: 22828689 Free article. No abstract available.
Baclofen.
Young RR. Young RR. Arch Neurol. 1977 Nov;34(11):722. doi: 10.1001/archneur.1977.00500230092023. Arch Neurol. 1977. PMID: 911241 No abstract available.
Intraventricular baclofen.
Park TS. Park TS. J Neurosurg. 2007 Sep;107(3 Suppl):224; discussion 224. doi: 10.3171/PED-07/09/224. J Neurosurg. 2007. PMID: 17918529 No abstract available.
Intrathecal baclofen.
Ochs GA. Ochs GA. Baillieres Clin Neurol. 1993 Apr;2(1):73-86. Baillieres Clin Neurol. 1993. PMID: 8143075 Review.
The intrathecal application of the GABA-B agonist baclofen has become more and more popular for severe spinal spasticity. ...In patients with supraspinal lesions causing muscle hypertension, where several mechanisms usually contribute besides hyper-reflexia (spasticity), t …
The intrathecal application of the GABA-B agonist baclofen has become more and more popular for severe spinal spasticity. ...In patie …
Enantioresolution of (RS)-baclofen by liquid chromatography: A review.
Batra S, Bhushan R. Batra S, et al. Biomed Chromatogr. 2017 Jan;31(1). doi: 10.1002/bmc.3833. Epub 2016 Oct 13. Biomed Chromatogr. 2017. PMID: 27591736 Review.
Baclofen is a commonly used racemic drug and has a simple chemical structure in terms of the presence of only one stereogenic center. ...This review summarizes and evaluates different methods of enantioseparation of (RS)-baclofen using both direct and indirect appro
Baclofen is a commonly used racemic drug and has a simple chemical structure in terms of the presence of only one stereogenic center.
8,486 results