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Year Number of Results
1966 1
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1978 4
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1981 1
1982 2
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1984 3
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1988 4
1989 3
1990 2
1991 2
1992 1
1993 5
1994 3
1995 3
1996 8
1997 5
1998 5
1999 6
2000 8
2001 9
2002 8
2003 5
2004 6
2005 3
2006 7
2007 6
2008 6
2009 3
2010 8
2011 5
2012 9
2013 10
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2017 5
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228 results

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Page 1
Comparison of disinfection effect between benzalkonium chloride and povidone iodine in nasotracheal intubation: a randomized trial.
Sato-Boku A, Nagano K, Hasegawa Y, Kamimura Y, Sento Y, So M, Kako E, Okuda M, Tachi N, Ito H, Adachi Y, Sobue K. Sato-Boku A, et al. BMC Anesthesiol. 2019 Aug 31;19(1):168. doi: 10.1186/s12871-019-0839-y. BMC Anesthesiol. 2019. PMID: 31470798 Free PMC article. Clinical Trial.
RESULTS: Although the initial disinfection effects (B/A) were inferior for benzalkonium chloride compared with those for povidone iodine, the effects were sustained for benzalkonium chloride (C/B). In the in vitro growth inhibitory assay against S. aureus, benzal …
RESULTS: Although the initial disinfection effects (B/A) were inferior for benzalkonium chloride compared with those for povidone iod …
Preservative-Free versus Benzalkonium Chloride-Preserved Latanoprost Ophthalmic Solution in Patients with Primary Open-Angle Glaucoma or Ocular Hypertension: A Phase 3 US Clinical Trial.
Bacharach J, Ahmed IIK, Sharpe ED, Korenfeld MS, Zhang S, Baudouin C. Bacharach J, et al. Clin Ophthalmol. 2023 Sep 1;17:2575-2588. doi: 10.2147/OPTH.S414015. eCollection 2023. Clin Ophthalmol. 2023. PMID: 37674591 Free PMC article. Clinical Trial.
PURPOSE: To evaluate the safety and efficacy of a preservative-free latanoprost 0.005% formulation (T2345) in patients with primary open-angle glaucoma (POAG) or ocular hypertension (OHT) compared to benzalkonium chloride-preserved latanoprost 0.005% (BPL) formulation in t …
PURPOSE: To evaluate the safety and efficacy of a preservative-free latanoprost 0.005% formulation (T2345) in patients with primary open-ang …
COMfort Eye Trial (COMET) results - a non-inferiority, randomized, investigator-masked, two-parallel group, phase III clinical trial, to evaluate the efficacy and safety of a preservative free formulation of latanoprost versus a reference drug (Xalatan®) in patients with primary open-angle glaucoma (POAG) or ocular hypertension (OHT).
Kandarakis S, Papadopoulos AP, Roussopoulos G, Georgopoulos E, Chung Y, Doumazos L, Baek A, Paizi NI, Shin H, Papadopoulos PA. Kandarakis S, et al. Expert Opin Drug Saf. 2024 Jun;23(6):743-754. doi: 10.1080/14740338.2023.2252341. Epub 2023 Sep 6. Expert Opin Drug Saf. 2024. PMID: 37674345 Clinical Trial.
AIM: To prove non-inferiority of preservative-free (PF) latanoprost versus benzalkonium chloride (BAK) containing latanoprost in lowering intraocular pressure (IOP) in primary open-angle glaucoma (POAG) or ocular hypertension (OHT) patients. ...
AIM: To prove non-inferiority of preservative-free (PF) latanoprost versus benzalkonium chloride (BAK) containing latanoprost in lowe …
A phase III, multicentre, randomised, investigator-masked, cross-over, comparative, non-inferiority trial evaluating the efficacy and tolerability of generic preservative-free Latanoprost (Polpharma S.A.) compared to Xalatan® (Pfizer) in patients with ocular hypertension or primary open-angle glaucoma.
Czumbel N, Acs T, Bator G, Halmosi A, Egorov EA, Maltsev DS. Czumbel N, et al. BMC Ophthalmol. 2024 Jul 29;24(1):313. doi: 10.1186/s12886-024-03579-3. BMC Ophthalmol. 2024. PMID: 39075412 Free PMC article. Clinical Trial.
Latanoprost Polpharma, being preservative-free, also avoids the cytotoxicity of benzalkonium chloride, the side effects of which may affect patient compliance and lower the quality of life. ...
Latanoprost Polpharma, being preservative-free, also avoids the cytotoxicity of benzalkonium chloride, the side effects of which may …
Efficacy of spray disinfection with a 2-propanol and benzalkonium chloride containing solution before epidural catheter insertion--a prospective, randomized, clinical trial.
Debreceni G, Meggyesi R, Mestyán G. Debreceni G, et al. Br J Anaesth. 2007 Jan;98(1):131-5. doi: 10.1093/bja/ael288. Epub 2006 Oct 30. Br J Anaesth. 2007. PMID: 17074778 Free article. Clinical Trial.
The first group (n=35) received disinfection with swabs (SW) containing 2-propanol and benzalkonium chloride. The other 35 patients received spray (SP) disinfection with the same solution. ...
The first group (n=35) received disinfection with swabs (SW) containing 2-propanol and benzalkonium chloride. The other 35 patients r …
Influence of timolol, benzalkonium-preserved timolol, and benzalkonium-preserved brimonidine on oxidative stress biomarkers in the tear film.
Sedlak L, Wojnar W, Zych M, Wyględowska-Promieńska D. Sedlak L, et al. Cutan Ocul Toxicol. 2020 Sep;39(3):260-268. doi: 10.1080/15569527.2020.1787435. Epub 2020 Jul 7. Cutan Ocul Toxicol. 2020. PMID: 32594785 Clinical Trial.
PURPOSE: The objective of this study was to investigate the influence of topical preservative-free timolol, benzalkonium chloride(BAC)-preserved timolol, BAC-preserved timolol, and BAC-preserved brimonidine on total protein concentration, advanced oxidation protein product …
PURPOSE: The objective of this study was to investigate the influence of topical preservative-free timolol, benzalkonium chloride(BAC …
Genomic and post-genomic effects of anti-glaucoma drugs preservatives in trabecular meshwork.
Izzotti A, La Maestra S, Micale RT, Longobardi MG, Saccà SC. Izzotti A, et al. Mutat Res. 2015 Feb;772:1-9. doi: 10.1016/j.mrfmmm.2014.11.006. Epub 2014 Dec 18. Mutat Res. 2015. PMID: 25772104 Clinical Trial.
Benzalkonium chloride, and polyQuad significantly increased oxidative DNA damage as compared to sham-treated specimens. Gene expression was altered by benzalkonium chloride, polyQuad, and purite but not by sofzia. In in vitro experiments, benzalkonium chlorid …
Benzalkonium chloride, and polyQuad significantly increased oxidative DNA damage as compared to sham-treated specimens. Gene expressi …
Transepithelial corneal crosslinking for keratoconus.
Hersh PS, Lai MJ, Gelles JD, Lesniak SP. Hersh PS, et al. J Cataract Refract Surg. 2018 Mar;44(3):313-322. doi: 10.1016/j.jcrs.2017.12.022. J Cataract Refract Surg. 2018. PMID: 29703286 Clinical Trial.
METHODS: Transepithelial CXL was performed in keratoconic eyes using riboflavin 0.1% and topical anesthetic containing benzalkonium chloride to facilitate riboflavin diffusion through the epithelium. Eyes were randomized to receive riboflavin administration either every 1 …
METHODS: Transepithelial CXL was performed in keratoconic eyes using riboflavin 0.1% and topical anesthetic containing benzalkonium c …
Safety and acceptability of vaginal disinfection with benzalkonium chloride in HIV infected pregnant women in west Africa: ANRS 049b phase II randomized, double blinded placebo controlled trial. DITRAME Study Group.
Msellati P, Meda N, Leroy V, Likikouët R, Van de Perre P, Cartoux M, Bonard D, Ouangre A, Combe P, Gautier-Charpentier L, Sylla-Koko F, Lassalle R, Dosso M, Welffens-Ekra C, Dabis F, Mandelbrot L. Msellati P, et al. Sex Transm Infect. 1999 Dec;75(6):420-5. doi: 10.1136/sti.75.6.420. Sex Transm Infect. 1999. PMID: 10754950 Free PMC article. Clinical Trial.
INTERVENTION: Women self administered daily a vaginal suppository of 1% benzalkonium chloride or matched placebo from 36 weeks of pregnancy, and a single intrapartum dose. ...In children, the incidence of dermatitis and conjunctivitis did not differ between the benzalko …
INTERVENTION: Women self administered daily a vaginal suppository of 1% benzalkonium chloride or matched placebo from 36 weeks of pre …
228 results