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Methaemoglobinaemia from Vagisil creme in a 50-year-old woman.
Cheyney S, Field Z, Kropf J, Carlan S. Cheyney S, et al. BMJ Case Rep. 2021 Mar 1;14(3):e239697. doi: 10.1136/bcr-2020-239697. BMJ Case Rep. 2021. PMID: 33649024 Free PMC article.
As methaemoglobin is unable to reversibly bind to oxygen potentially lethal hypoxia and functional anaemia can occur. Benzocaine can be used as a topical anaesthetic and can be found in many nonprescription preparations marketed for self-application. ...Methaemoglobinaemia …
As methaemoglobin is unable to reversibly bind to oxygen potentially lethal hypoxia and functional anaemia can occur. Benzocaine can …
Case Report: An Uncommon Etiology of Vulvar Irritation and Swelling in an Adolescent Patient.
Bloomfield V, Murphy N, Kives S. Bloomfield V, et al. J Pediatr Adolesc Gynecol. 2022 Dec;35(6):715-717. doi: 10.1016/j.jpag.2022.07.014. Epub 2022 Aug 4. J Pediatr Adolesc Gynecol. 2022. PMID: 35934185
His clinical course was complicated by an episode of methemoglobinemia secondary to local anesthetic toxicity, at which time his care team recognized use of large quantities of Vagisil, which contains benzocaine. Ultimately, vulvar changes were recognized to be secondary t …
His clinical course was complicated by an episode of methemoglobinemia secondary to local anesthetic toxicity, at which time his care team r …
Methemoglobinemia induced by an over-the-counter medication.
Tush GM, Kuhn RJ. Tush GM, et al. Ann Pharmacother. 1996 Nov;30(11):1251-4. doi: 10.1177/106002809603001109. Ann Pharmacother. 1996. PMID: 8913407
OBJECTIVE: To report a case of methemoglobinemia induced by benzocaine and resorcinol (Vagisil) cream, an over-the-counter medication that was used to treat diaper rash in a neonate. ...Methemoglobinemia secondary to absorption of benzocaine and resorcinol …
OBJECTIVE: To report a case of methemoglobinemia induced by benzocaine and resorcinol (Vagisil) cream, an over-the-counter med …
Unusual cause of severe toxic methemoglobinemia in an infant: a case report.
Bouziri A, Khaldi A, Menif K, Ben Jaballah N. Bouziri A, et al. Int J Emerg Med. 2010 Feb 27;3(1):57-9. doi: 10.1007/s12245-009-0149-0. Int J Emerg Med. 2010. PMID: 20414384 Free PMC article.
We report an unusual case of severe toxic methemoglobinemia following wide cutaneous application of a pomade containing benzocaine, resorcin, and oxyquinoline (Nestosyl) in an infant....
We report an unusual case of severe toxic methemoglobinemia following wide cutaneous application of a pomade containing benzocaine, r …
Potential for an external vaginal antiitch cream containing benzocaine to cause methemoglobinemia in healthy women.
Currie JL, Mott LA, Pennisi SC, Smith BD, Smith RP. Currie JL, et al. Am J Obstet Gynecol. 1997 May;176(5):1006-8. doi: 10.1016/s0002-9378(97)70393-4. Am J Obstet Gynecol. 1997. PMID: 9166159
OBJECTIVES: Our purpose was to assess the potential for an external vaginal antiitch cream (20% benzocaine, 3% resorcinol) to significantly increase levels of methemoglobin above normal in healthy women. ...
OBJECTIVES: Our purpose was to assess the potential for an external vaginal antiitch cream (20% benzocaine, 3% resorcinol) to …