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34 results

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Page 1
Benzonatate Safety and Effectiveness: A Systematic Review of the Literature.
Costantino RC, Leonard J, Gorman EF, Ventura D, Baltz A, Gressler LE. Costantino RC, et al. Ann Pharmacother. 2023 Oct;57(10):1221-1236. doi: 10.1177/10600280221135750. Epub 2023 Jan 23. Ann Pharmacother. 2023. PMID: 36688284 Review.
OBJECTIVE: To review the available literature regarding the treatment effects and efficacy of benzonatate needed to better inform patients, providers, and regulators evaluating its role in modern medical therapies. ...Initial clinical studies exploring potential therape
OBJECTIVE: To review the available literature regarding the treatment effects and efficacy of benzonatate needed to better inform pat …
Benzonatate Exposure Trends and Adverse Events.
Kim I, Goulding M, Tian F, Karami S, Pham T, Cheng C, Biehl A, Muñoz M. Kim I, et al. Pediatrics. 2022 Dec 1;150(6):e2022057779. doi: 10.1542/peds.2022-057779. Pediatrics. 2022. PMID: 36377394 Free PMC article.
There were few cases annually of serious AEs with benzonatate in children. CONCLUSIONS: There were rising patterns of unintentional ingestion of benzonatate in children 0 to 5 years old and intentional benzonatate ingestion in children 10 to 16 years old. Rat …
There were few cases annually of serious AEs with benzonatate in children. CONCLUSIONS: There were rising patterns of unintentional i …
Drugs for cough.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2018 Dec 17;60(1562):206-208. Med Lett Drugs Ther. 2018. PMID: 30625123 Review. No abstract available.
In brief: benzonatate warning.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2011 Feb 7;53(1357):9. Med Lett Drugs Ther. 2011. PMID: 21304443 Review. No abstract available.
Benzonatate Toxicity: Nothing to Cough At.
Bishop-Freeman SC, Shonsey EM, Friederich LW, Beuhler MC, Winecker RE. Bishop-Freeman SC, et al. J Anal Toxicol. 2017 Jun 1;41(5):461-463. doi: 10.1093/jat/bkx021. J Anal Toxicol. 2017. PMID: 28334901 No abstract available.
Analysis of benzonatate overdoses among adults and children from 1969-2010 by the United States Food and Drug Administration.
McLawhorn MW, Goulding MR, Gill RK, Michele TM. McLawhorn MW, et al. Pharmacotherapy. 2013 Jan;33(1):38-43. doi: 10.1002/phar.1153. Pharmacotherapy. 2013. PMID: 23307543
STUDY OBJECTIVE: To augment the December 2010 United States Food and Drug Administration (FDA) Drug Safety Communication on accidental ingestion of benzonatate in children less than 10 years old by summarizing data on emergency department visits, benzonatate exposur …
STUDY OBJECTIVE: To augment the December 2010 United States Food and Drug Administration (FDA) Drug Safety Communication on accidental inges …
Cardiac Arrest Due to Benzonatate Overdose.
Jin C, Zahid E, Sherazi A, Majumder MR, Bedi P. Jin C, et al. Am J Case Rep. 2019 May 3;20:640-642. doi: 10.12659/AJCR.915151. Am J Case Rep. 2019. PMID: 31048669 Free PMC article.
BACKGROUND Benzonatate is one of the most widely prescribed nonnarcotic antitussives to relieve cough symptoms. ...It was reported that approximately 2 hours prior to her presentation; the patient had ingested less than 30 pills of benzonatate 200 mg capsules with a …
BACKGROUND Benzonatate is one of the most widely prescribed nonnarcotic antitussives to relieve cough symptoms. ...It was reported th …
Management of cough in advanced cancer.
Estfan B, LeGrand S. Estfan B, et al. J Support Oncol. 2004 Nov-Dec;2(6):523-7. J Support Oncol. 2004. PMID: 16302303 Review.
We prefer hydrocodone as first-line empiric treatment, but when the cough is resistant to this, our second-line therapy would be the addition or substitution of benzonatate. Bronchodilators, as well as corticosteroids, are commonly employed in our practice and can be usefu …
We prefer hydrocodone as first-line empiric treatment, but when the cough is resistant to this, our second-line therapy would be the additio …
Nebulized lidocaine in the treatment of intractable cough.
Truesdale K, Jurdi A. Truesdale K, et al. Am J Hosp Palliat Care. 2013 Sep;30(6):587-9. doi: 10.1177/1049909112458577. Epub 2012 Sep 9. Am J Hosp Palliat Care. 2013. PMID: 22964341 Review.
Pharmacological treatments include dextramethorphan, opioid cough suppressants, benzonatate, inhaled ipratropium, and guaifenesin. Successful cough suppression has also been demonstrated in several studies with the use of nebulized lidocaine. ...
Pharmacological treatments include dextramethorphan, opioid cough suppressants, benzonatate, inhaled ipratropium, and guaifenesin. Su …
Benzonatate overdose associated with seizures and arrhythmias.
Crouch BI, Knick KA, Crouch DJ, Matsumura KS, Rollins DE. Crouch BI, et al. J Toxicol Clin Toxicol. 1998;36(7):713-8. doi: 10.3109/15563659809162620. J Toxicol Clin Toxicol. 1998. PMID: 9865240
Therefore, laboratory analysis of benzonatate is difficult. We report 2 cases of benzonatate poisoning with seizures and cardiac arrest and an analytical method to identify and quantify benzonatate in human plasma. ...Routine analysis for benzonatate i …
Therefore, laboratory analysis of benzonatate is difficult. We report 2 cases of benzonatate poisoning with seizures and cardi …
34 results