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Year Number of Results
1966 1
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1979 4
1982 2
1983 4
1984 3
1986 2
1987 7
1988 3
1989 7
1990 5
1991 5
1992 2
1993 4
1994 4
1995 2
1996 5
1997 4
1998 2
1999 1
2000 4
2001 4
2002 2
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127 results

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Page 1
Benztropine and suicide attempts and intentional self-harm.
Gibbons RD, Hur K, Lavigne JE, Mann JJ. Gibbons RD, et al. Psychiatry Res. 2023 Feb;320:115054. doi: 10.1016/j.psychres.2023.115054. Epub 2023 Jan 7. Psychiatry Res. 2023. PMID: 36638693 Clinical Trial.
BACKGROUND: This large-scale pharmacoepidemiologic study was conducted to confirm a previous signal for decreased risk of suicide attempt following prescription fills for benztropine. METHODS: We used a within-person exposure-only cohort design to study the dynamic associa …
BACKGROUND: This large-scale pharmacoepidemiologic study was conducted to confirm a previous signal for decreased risk of suicide attempt fo …
The effect of benztropine on haloperidol-induced dystonia, clinical efficacy and pharmacokinetics: a prospective, double-blind trial.
Goff DC, Arana GW, Greenblatt DJ, Dupont R, Ornsteen M, Harmatz JS, Shader RI. Goff DC, et al. J Clin Psychopharmacol. 1991 Apr;11(2):106-12. J Clin Psychopharmacol. 1991. PMID: 2056136 Clinical Trial.
Twenty-nine inpatients with major psychotic disorders were treated for 14 days with a clinician-determined dose of haloperidol and with either benztropine or placebo given by double-blind random assignment on days 1 through 7. No differences were noted in haloperidol mean …
Twenty-nine inpatients with major psychotic disorders were treated for 14 days with a clinician-determined dose of haloperidol and with eith …
Treatment of valproate tremors.
Karas BJ, Wilder BJ, Hammond EJ, Bauman AW. Karas BJ, et al. Neurology. 1983 Oct;33(10):1380-2. doi: 10.1212/wnl.33.10.1380. Neurology. 1983. PMID: 6412157 Clinical Trial.
We studied the effects of propranolol, amantadine, diphenhydramine, benztropine, and cyproheptadine on these tremors in 19 patients by using serial accelerometric recordings. ...Amantadine was moderately effective, but cyproheptadine, diphenhydramine, and benztropine
We studied the effects of propranolol, amantadine, diphenhydramine, benztropine, and cyproheptadine on these tremors in 19 patients b …
Efficacy of benztropine therapy for drooling.
Camp-Bruno JA, Winsberg BG, Green-Parsons AR, Abrams JP. Camp-Bruno JA, et al. Dev Med Child Neurol. 1989 Jun;31(3):309-19. doi: 10.1111/j.1469-8749.1989.tb04000.x. Dev Med Child Neurol. 1989. PMID: 2666205 Clinical Trial.
This study assessed the efficacy of synthetic anticholinergic benztropine and incidence of side-effects in 20 developmentally-disabled patients with severe drooling. The double-blind, placebo-controlled, crossover protocol included one-week baseline, two-week placebo and t …
This study assessed the efficacy of synthetic anticholinergic benztropine and incidence of side-effects in 20 developmentally-disable …
Effectiveness and cost of olanzapine and haloperidol in the treatment of schizophrenia: a randomized controlled trial.
Rosenheck R, Perlick D, Bingham S, Liu-Mares W, Collins J, Warren S, Leslie D, Allan E, Campbell EC, Caroff S, Corwin J, Davis L, Douyon R, Dunn L, Evans D, Frecska E, Grabowski J, Graeber D, Herz L, Kwon K, Lawson W, Mena F, Sheikh J, Smelson D, Smith-Gamble V; Department of Veterans Affairs Cooperative Study Group on the Cost-Effectiveness of Olanzapine. Rosenheck R, et al. JAMA. 2003 Nov 26;290(20):2693-702. doi: 10.1001/jama.290.20.2693. JAMA. 2003. PMID: 14645311 Clinical Trial.
INTERVENTIONS: Patients were randomly assigned to receive flexibly dosed olanzapine, 5 to 20 mg/d, with prophylactic benztropine, 1 to 4 mg/d (n = 159); or haloperidol, 5 to 20 mg/d (n = 150), for 12 months. ...CONCLUSION: Olanzapine does not demonstrate advantages compare …
INTERVENTIONS: Patients were randomly assigned to receive flexibly dosed olanzapine, 5 to 20 mg/d, with prophylactic benztropine, 1 t …
A comparative study of haloperidol and chlorpromazine in terms of clinical effects and therapeutic reversal with benztropine in schizophrenia. Theoretical implications for potency differences among neuroleptics.
Singh MM, Kay SR. Singh MM, et al. Psychopharmacologia. 1975 Aug 21;43(2):103-13. doi: 10.1007/BF00421012. Psychopharmacologia. 1975. PMID: 1103205 Clinical Trial.
The data failed to support the clinical validity of the distinction often made between "sedative" and "activating" neuroleptics. Consistent with previous reports, benztropine had the effect of diminishing therapeutic response to both neuroleptics. However, haloperidol agai …
The data failed to support the clinical validity of the distinction often made between "sedative" and "activating" neuroleptics. Consistent …
Akathisia and exacerbation of psychopathology: a preliminary report.
Duncan EJ, Adler LA, Stephanides M, Sanfilipo M, Angrist B. Duncan EJ, et al. Clin Neuropharmacol. 2000 May-Jun;23(3):169-73. doi: 10.1097/00002826-200005000-00008. Clin Neuropharmacol. 2000. PMID: 10895402 Clinical Trial.
This study assessed changes in akathisia and psychopathology in 19 patients after separate one-day treatments with intramuscular benztropine and oral propranolol. Benztropine and propranolol led to clinically meaningful and statistically significant decrements in ra …
This study assessed changes in akathisia and psychopathology in 19 patients after separate one-day treatments with intramuscular benztrop
Ethopropazine and benztropine in neuroleptic-induced parkinsonism.
Chouinard G, Annable L, Ross-Chouinard A, Kropsky ML. Chouinard G, et al. J Clin Psychiatry. 1979 Mar;40(3):147-52. J Clin Psychiatry. 1979. PMID: 33969 Clinical Trial.
In a 12-week controlled study ethopropazine was compared to benztropine in the treatment of parkinsonism induced by fluphenazine enanthate in 60 schizophrenic outpatients. Ethopropazine and benztropine were found to be equally effective in controlling parkinsonian s …
In a 12-week controlled study ethopropazine was compared to benztropine in the treatment of parkinsonism induced by fluphenazine enan …
Intravenous benztropine and propranolol challenges in tardive akathisia.
Sachdev P, Loneragan C. Sachdev P, et al. Psychopharmacology (Berl). 1993;113(1):119-22. doi: 10.1007/BF02244343. Psychopharmacology (Berl). 1993. PMID: 7862817 Clinical Trial.
We challenged five patients suffering from tardive akathisia (TA) with intravenous benztropine (2 mg), propranolol (1 mg) and placebo (saline) using a random, double-blind cross-over design to examine the effects of the drugs on the subjective, objective and global manifes …
We challenged five patients suffering from tardive akathisia (TA) with intravenous benztropine (2 mg), propranolol (1 mg) and placebo …
Pharmacologic characterization of tardive dyskinesia.
Lieberman J, Pollack S, Lesser M, Kane J. Lieberman J, et al. J Clin Psychopharmacol. 1988 Aug;8(4):254-60. J Clin Psychopharmacol. 1988. PMID: 3209717 Clinical Trial.
To evaluate pharmacologic response in TD syndromes, 15 patients underwent single dose acute administration of four different drugs: a DA agonist (bromocriptine 5 mg orally), a DA antagonist (haloperidol 5 mg intravenously), a cholinergic agonist (physostigmine 2 mg intravenously) …
To evaluate pharmacologic response in TD syndromes, 15 patients underwent single dose acute administration of four different drugs: a DA ago …
127 results