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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 2
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1998 7
1999 7
2000 17
2001 19
2002 22
2003 29
2004 25
2005 28
2006 37
2007 36
2008 51
2009 27
2010 26
2011 41
2012 53
2013 56
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1,029 results

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Page 1
Bexarotene.
Lowe MN, Plosker GL. Lowe MN, et al. Am J Clin Dermatol. 2000 Jul-Aug;1(4):245-50; discussion 251-2. doi: 10.2165/00128071-200001040-00006. Am J Clin Dermatol. 2000. PMID: 11702369 Review.
An overall response rate of 63% was reported after topical bexarotene 0.1 to 1% twice daily in patients with early stage CTCL. Another trial reported an overall response rate of 44% after topical bexarotene 1% once daily escalated up to 4 times daily. Plaque elevati …
An overall response rate of 63% was reported after topical bexarotene 0.1 to 1% twice daily in patients with early stage CTCL. Anothe …
Bexarotene.
[No authors listed] [No authors listed] Am J Health Syst Pharm. 2000 Dec 1;57(23):2167. doi: 10.1093/ajhp/57.23.2167. Am J Health Syst Pharm. 2000. PMID: 11127695 No abstract available.
Bexarotene ligand pharmaceuticals.
Hurst RE. Hurst RE. Curr Opin Investig Drugs. 2000 Dec;1(4):514-23. Curr Opin Investig Drugs. 2000. PMID: 11249708 Review.
Bexarotene (LGD-1069), from Ligand, was the first retinoid X receptor (RXR)-selective, antitumor retinoid to enter clinical trials. ...Ligand has worldwide rights to market bexarotene capsules, and will market the drug in the US, Canada and selected European markets …
Bexarotene (LGD-1069), from Ligand, was the first retinoid X receptor (RXR)-selective, antitumor retinoid to enter clinical trials. . …
From the editor.
Garner JD. Garner JD. J Women Aging. 2014;26(1):1-2. doi: 10.1080/08952841.2013.815562. J Women Aging. 2014. PMID: 24483279 No abstract available.
Potential therapeutic uses of rexinoids.
Leal AS, Reich LA, Moerland JA, Zhang D, Liby KT. Leal AS, et al. Adv Pharmacol. 2021;91:141-183. doi: 10.1016/bs.apha.2021.01.004. Epub 2021 Mar 4. Adv Pharmacol. 2021. PMID: 34099107 Review.
Genetic models using deletion or overexpression of RXR and the subsequent development of several small molecules that are agonists or antagonists of this receptor support a promising therapeutic role for these receptors in immunology. Bexarotene was approved in 1999 for th …
Genetic models using deletion or overexpression of RXR and the subsequent development of several small molecules that are agonists or antago …
Bexarotene: a clinical review.
Farol LT, Hymes KB. Farol LT, et al. Expert Rev Anticancer Ther. 2004 Apr;4(2):180-8. doi: 10.1586/14737140.4.2.180. Expert Rev Anticancer Ther. 2004. PMID: 15056048 Review.
Bexarotene (Targretin, Ligand Pharmaceuticals Inc.) is a synthetic retinoid analog with specific affinity for the retinoid X receptor and belongs to a group of compounds called rexinoids. ...Subsequent Phase II/III trials have demonstrated a greater than 50% response rate …
Bexarotene (Targretin, Ligand Pharmaceuticals Inc.) is a synthetic retinoid analog with specific affinity for the retinoid X receptor …
The novel function of bexarotene for neurological diseases.
Liu Y, Wang P, Jin G, Shi P, Zhao Y, Guo J, Yin Y, Shao Q, Li P, Yang P. Liu Y, et al. Ageing Res Rev. 2023 Sep;90:102021. doi: 10.1016/j.arr.2023.102021. Epub 2023 Jul 24. Ageing Res Rev. 2023. PMID: 37495118 Review.
Bexarotene, a retinoid X receptor (RXR) agonist, is approved by FDA to treat cutaneous T-cell lymphoma. ...Here, we briefly discuss the characteristics, applications, and adverse effects of bexarotene, summarize its pharmacological mechanisms and therapeutic results …
Bexarotene, a retinoid X receptor (RXR) agonist, is approved by FDA to treat cutaneous T-cell lymphoma. ...Here, we briefly discuss t …
T-cell lymphoma products.
Bell TJ. Bell TJ. Nurse Pract. 2001 Mar;26(3):19. doi: 10.1097/00006205-200103000-00005. Nurse Pract. 2001. PMID: 11270155 No abstract available.
Bexarotene ameliorated the pulmonary inflammation and M1 polarization of alveolar macrophages induced by cigarette smoke via PPARgamma/HO-1.
Feng H, Li Z, Zheng R. Feng H, et al. Respir Res. 2024 Dec 18;25(1):431. doi: 10.1186/s12931-024-03064-x. Respir Res. 2024. PMID: 39696251 Free PMC article.
This study explored the effects and mechanisms of the RXRalpha agonist bexarotene on macrophage polarization in a COPD mouse model. METHODS: C57BL/6 mice were assigned to the control, model, bexarotene, or model + bexarotene group. ...Notably, the effect of …
This study explored the effects and mechanisms of the RXRalpha agonist bexarotene on macrophage polarization in a COPD mouse model. M …
Bexarotene: a promising anticancer agent.
Qu L, Tang X. Qu L, et al. Cancer Chemother Pharmacol. 2010 Jan;65(2):201-5. doi: 10.1007/s00280-009-1140-4. Epub 2009 Sep 24. Cancer Chemother Pharmacol. 2010. PMID: 19777233 Review.
The biologic effects of retinoids are mediated by two distinct families of intracellular receptors: retinoid acid receptors (RARs)-alpha, -beta and -gamma and retinoid X receptors (RXR)-alpha, -beta and -gamma. Bexarotene is a selective RXR agonist, which exerts its effect …
The biologic effects of retinoids are mediated by two distinct families of intracellular receptors: retinoid acid receptors (RARs)-alpha, -b …
1,029 results