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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 5
1985 8
1986 49
1987 25
1988 13
1989 15
1990 46
1991 16
1992 21
1993 22
1994 34
1995 29
1996 30
1997 30
1998 38
1999 50
2000 56
2001 59
2002 56
2003 61
2004 48
2005 48
2006 52
2007 61
2008 53
2009 70
2010 72
2011 59
2012 79
2013 80
2014 83
2015 97
2016 102
2017 85
2018 77
2019 88
2020 102
2021 129
2022 112
2023 26
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1,997 results
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Effect of Digoxin vs Bisoprolol for Heart Rate Control in Atrial Fibrillation on Patient-Reported Quality of Life: The RATE-AF Randomized Clinical Trial.
Kotecha D, Bunting KV, Gill SK, Mehta S, Stanbury M, Jones JC, Haynes S, Calvert MJ, Deeks JJ, Steeds RP, Strauss VY, Rahimi K, Camm AJ, Griffith M, Lip GYH, Townend JN, Kirchhof P; Rate Control Therapy Evaluation in Permanent Atrial Fibrillation (RATE-AF) Team. Kotecha D, et al. JAMA. 2020 Dec 22;324(24):2497-2508. doi: 10.1001/jama.2020.23138. JAMA. 2020. PMID: 33351042 Free PMC article. Clinical Trial.
INTERVENTIONS: Digoxin (n = 80; dose range, 62.5-250 mug/d; mean dose, 161 mug/d) or bisoprolol (n = 80; dose range, 1.25-15 mg/d; mean dose, 3.2 mg/d). ...Adverse events were less common with digoxin; 20 patients (25%) in the digoxin group had at least 1 AE vs 51 patients …
INTERVENTIONS: Digoxin (n = 80; dose range, 62.5-250 mug/d; mean dose, 161 mug/d) or bisoprolol (n = 80; dose range, 1.25-15 mg/d; me …
Bisoprolol: A comprehensive profile.
Bakheit AH, Ali R, Alshahrani AD, El-Azab AS. Bakheit AH, et al. Profiles Drug Subst Excip Relat Methodol. 2021;46:51-89. doi: 10.1016/bs.podrm.2020.07.006. Epub 2020 Sep 8. Profiles Drug Subst Excip Relat Methodol. 2021. PMID: 33461700
The present study describes a comprehensive profile of Bisoprolol including detailed nomenclature; formulae, elemental analysis, appearance, its uses, applications, and methods for the preparation are outlined. ...The mass fragmentation pattern of bisoprolol fumarat …
The present study describes a comprehensive profile of Bisoprolol including detailed nomenclature; formulae, elemental analysis, appe …
Beta-blockers for the treatment of arrhythmias: Bisoprolol - a systematic review.
Muresan L, Cismaru G, Muresan C, Rosu R, Gusetu G, Puiu M, Mada RO, Martins RP. Muresan L, et al. Ann Pharm Fr. 2022 Sep;80(5):617-634. doi: 10.1016/j.pharma.2022.01.007. Epub 2022 Jan 31. Ann Pharm Fr. 2022. PMID: 35093388 Free article. Review.
The aim of this study was to analyze the current existing evidence for bisoprolol for the treatment of both supraventricular and ventricular arrhythmias. MATERIAL AND METHODS: Using the keywords "bisoprolol" and "arrhythmias" or "atrial fibrillation" or "ventricular …
The aim of this study was to analyze the current existing evidence for bisoprolol for the treatment of both supraventricular and vent …
Management of Hypertension With a Fixed-Dose (Single-Pill) Combination of Bisoprolol and Amlodipine.
Gottwald-Hostalek U, Sun N, Barho C, Hildemann S. Gottwald-Hostalek U, et al. Clin Pharmacol Drug Dev. 2017 Jan;6(1):9-18. doi: 10.1002/cpdd.309. Epub 2016 Oct 26. Clin Pharmacol Drug Dev. 2017. PMID: 27653022
Among combinations of hypertension medications, a beta-blocker such as bisoprolol with a calcium channel blocker such as amlodipine is an effective combination therapy for hypertension, with distinct and complimentary modes of action. With advantages over free-dose combina …
Among combinations of hypertension medications, a beta-blocker such as bisoprolol with a calcium channel blocker such as amlodipine i …
Pharmacogenetic polymorphisms affecting bisoprolol response.
Castaño-Amores C, Díaz-Villamarín X, Pérez-Gutiérrez AM, Antúnez-Rodríguez A, Pozo-Agundo A, Moreno-Escobar E, Sánchez-Ramos JG, Martínez-González LJ, Dávila-Fajardo CL. Castaño-Amores C, et al. Biomed Pharmacother. 2021 Oct;142:112069. doi: 10.1016/j.biopha.2021.112069. Epub 2021 Aug 27. Biomed Pharmacother. 2021. PMID: 34470728 Free article.
The ADRB1 Arg389Gly (rs1801253) was the most studied genetic polymorphism and it seems to influence the response to bisoprolol, although studies are inconclusive. Even, we performed a meta-analysis about its influence on systolic/diastolic blood pressure in patients treate …
The ADRB1 Arg389Gly (rs1801253) was the most studied genetic polymorphism and it seems to influence the response to bisoprolol, altho …
Use of the oral beta blocker bisoprolol to reduce the rate of exacerbation in people with chronic obstructive pulmonary disease (COPD): a randomised controlled trial (BICS).
Cotton S, Devereux G, Abbas H, Briggs A, Campbell K, Chaudhuri R, Choudhury G, Dawson D, De Soyza A, Fielding S, Gompertz S, Haughney J, Lang CC, Lee AJ, MacLennan G, MacNee W, McCormack K, McMeekin N, Mills NL, Morice A, Norrie J, Petrie MC, Price D, Short P, Vestbo J, Walker P, Wedzicha J, Wilson A, Lipworth BJ. Cotton S, et al. Trials. 2022 Apr 14;23(1):307. doi: 10.1186/s13063-022-06226-8. Trials. 2022. PMID: 35422024 Free PMC article. Clinical Trial.
Observational studies consistently report that beta blocker use in people with COPD is associated with a reduced risk of COPD exacerbations. The bisoprolol in COPD study (BICS) investigates whether adding bisoprolol to routine COPD treatment has clinical and cost-ef …
Observational studies consistently report that beta blocker use in people with COPD is associated with a reduced risk of COPD exacerbations. …
Recent advances in understanding and managing resistant/refractory hypertension.
Doumas M, Imprialos KP, Kallistratos MS, Manolis AJ. Doumas M, et al. F1000Res. 2020 Mar 9;9:F1000 Faculty Rev-169. doi: 10.12688/f1000research.21669.1. eCollection 2020. F1000Res. 2020. PMID: 32201574 Free PMC article. Review.
During the past few years, several studies have been performed to identify efficient and safe pharmacological and non-pharmacological options for the management of such patients. The Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatmen …
During the past few years, several studies have been performed to identify efficient and safe pharmacological and non-pharmacological option …
Therapeutic Properties of Highly Selective β-blockers With or Without Additional Vasodilator Properties: Focus on Bisoprolol and Nebivolol in Patients With Cardiovascular Disease.
AlHabeeb W, Mrabeti S, Abdelsalam AAI. AlHabeeb W, et al. Cardiovasc Drugs Ther. 2022 Oct;36(5):959-971. doi: 10.1007/s10557-021-07205-y. Epub 2021 Jun 9. Cardiovasc Drugs Ther. 2022. PMID: 34106365 Free PMC article. Review.
Bisoprolol and nebivolol are highly selective beta(1)-adrenoceptor antagonists, with clinical indications in many countries within the management of heart failure with reduced left ventricular ejection fraction (HFrEF), ischaemic heart disease (IHD), and hypertension. ...I …
Bisoprolol and nebivolol are highly selective beta(1)-adrenoceptor antagonists, with clinical indications in many countries within th …
Effects of carvedilol vs bisoprolol on inflammation and oxidative stress in patients with chronic heart failure.
Toyoda S, Haruyama A, Inami S, Arikawa T, Saito F, Watanabe R, Sakuma M, Abe S, Nakajima T, Tanaka A, Node K, Inoue T. Toyoda S, et al. J Cardiol. 2020 Feb;75(2):140-147. doi: 10.1016/j.jjcc.2019.07.011. Epub 2019 Aug 21. J Cardiol. 2020. PMID: 31444140 Free article. Clinical Trial.
In all 48 patients, the change in hsTnT was correlated with that in hsCRP (R = 0.467, p = 0.003). CONCLUSIONS: Bisoprolol may be better than carvedilol for reducing inflammation, but carvedilol may be better than bisoprolol for reducing oxidative stress. Proper use …
In all 48 patients, the change in hsTnT was correlated with that in hsCRP (R = 0.467, p = 0.003). CONCLUSIONS: Bisoprolol may be bett …
A growing evidence base for the fixed-dose combination of bisoprolol and amlodipine to manage hypertension.
Hostalek-Gottwald U, Gaciong Z. Hostalek-Gottwald U, et al. Curr Med Res Opin. 2022 Jul;38(7):1047-1053. doi: 10.1080/03007995.2022.2072087. Epub 2022 May 13. Curr Med Res Opin. 2022. PMID: 35510372 Review.
In a large cohort study exploring FDC bisoprolol and amlodipine in daily practice, high adherence improved BP and heart rate control versus baseline. ...CONCLUSIONS: This review adds to growing evidence supporting the efficacy, safety, and tolerability of FDC bisoprolol …
In a large cohort study exploring FDC bisoprolol and amlodipine in daily practice, high adherence improved BP and heart rate control …
1,997 results