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118 results

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Page 1
Drugs for hypertension.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2024 May 27;66(1703):81-88. doi: 10.58347/tml.2024.1703a. Med Lett Drugs Ther. 2024. PMID: 38771738 Review. No abstract available.
Efficacy and Safety of Low-Dose Bisoprolol/Hydrochlorothiazide Combination for the Treatment of Hypertension: A Systematic Review and Meta-Analysis.
Cicero AFG, ALGhasab NS, Tocci G, Desideri G, Fiorini G, Fogacci F. Cicero AFG, et al. J Clin Med. 2024 Aug 5;13(15):4572. doi: 10.3390/jcm13154572. J Clin Med. 2024. PMID: 39124839 Free PMC article. Review.
Finally, treatment with low-dose bisoprolol/hydrochlorothiazide was associated with a reduced risk of any adverse event (AE) and peripheral edema compared to control. Conclusions: Overall, our results reaffirm the safety and efficiency of prescribing bisoprolol …
Finally, treatment with low-dose bisoprolol/hydrochlorothiazide was associated with a reduced risk of any adverse event (AE) a …
Drugs for hypertension.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2020 May 18;62(1598):73-80. Med Lett Drugs Ther. 2020. PMID: 32555118 No abstract available.
Bisoprolol and hydrochlorothiazide effects on cardiovascular remodeling in spontaneously hypertensive rats.
Mougenot N, Médiani O, Lechat P. Mougenot N, et al. Pharmacol Res. 2005 Apr;51(4):359-65. doi: 10.1016/j.phrs.2004.10.010. Pharmacol Res. 2005. PMID: 15683750
Rats were divided into four groups: control, bisoprolol (100 mg kg-1), hydrochlorothiazide (10 mg kg-1), and their combination with low doses (10 and 1 mg kg-1, respectively). ...The combination had synergistic anti-hypertensive effects and significantly reduced hea …
Rats were divided into four groups: control, bisoprolol (100 mg kg-1), hydrochlorothiazide (10 mg kg-1), and their combination …
Myocardial damage in a 4-year old who ingested bisoprolol and hydrochlorothiazide - Incidental CK-BB highlighted other tissue toxicity.
Zangardi T, Altinier S, Mion MM, Cennamo M, Aita A, Bressan S, Basso D. Zangardi T, et al. Clin Biochem. 2025 Dec;140:111028. doi: 10.1016/j.clinbiochem.2025.111028. Epub 2025 Oct 10. Clin Biochem. 2025. PMID: 41076179 Free article.
INTRODUCTION: A 4-year-old girl accidentally ingested an unknown quantity of bisoprolol (2.5 mg)-hydrochlorothiazide (6.25 mg) pills. Initialy asymptomatic, laboratory testing revealed elevated concentrations of cardiac and skeletal muscle injury markers. ...CONCLUS …
INTRODUCTION: A 4-year-old girl accidentally ingested an unknown quantity of bisoprolol (2.5 mg)-hydrochlorothiazide (6.25 mg) …
[Efficacy and tolerance of the bisoprolol/hydrochlorothiazide combination in arterial hypertension].
Luna RL, Oigman W, Ramirez JA, Mion D, Batlouni M, da Rocha JC, Feitosa GS, Castro I, Chaves Júnior Hde C, God EM, Maia LN, Ortega KC, Raineri AM. Luna RL, et al. Arq Bras Cardiol. 1998 Oct;71(4):601-8. doi: 10.1590/s0066-782x1998001000008. Arq Bras Cardiol. 1998. PMID: 10347937 Clinical Trial. Portuguese.
PURPOSE: Multicenter, open and non-controlled study to evaluated the efficacy and the tolerability of a low-dose combination of two anti-hypertensive agents: a cardioselective beta-blocker, bisoprolol (2.5 and 5.0 mg) with 6.25 mg of hydrochlorothiazide. METHODS: On …
PURPOSE: Multicenter, open and non-controlled study to evaluated the efficacy and the tolerability of a low-dose combination of two anti-hyp …
Mathematical modeling of antihypertensive therapy.
Kutumova E, Kiselev I, Sharipov R, Lifshits G, Kolpakov F. Kutumova E, et al. Front Physiol. 2022 Dec 14;13:1070115. doi: 10.3389/fphys.2022.1070115. eCollection 2022. Front Physiol. 2022. PMID: 36589434 Free PMC article.
For this, we used the pharmacodynamic effects of the angiotensin II receptor blocker losartan, the calcium channel blocker amlodipine, the angiotensin-converting enzyme inhibitor enalapril, the direct renin inhibitor aliskiren, the thiazide diuretic hydrochlorothiazide, an …
For this, we used the pharmacodynamic effects of the angiotensin II receptor blocker losartan, the calcium channel blocker amlodipine, the a …
Development and Validation of an UPLC-MS/MS Method for Simultaneous Quantification of Bisoprolol and Hydrochlorothiazide in Human Plasma.
Al-Asmar A, Kittana N, Mayyala A, Asmar I, Hussein A. Al-Asmar A, et al. J Mass Spectrom. 2025 Aug;60(8):e5159. doi: 10.1002/jms.5159. J Mass Spectrom. 2025. PMID: 40717234
This research focuses on developing and validating a UPLC-MS/MS method for the simultaneous determination of bisoprolol and hydrochlorothiazide in human plasma, adhering to established regulatory guidelines for bioanalytical method validation. ...The analytes and th …
This research focuses on developing and validating a UPLC-MS/MS method for the simultaneous determination of bisoprolol and hydroc …
Simultaneous determination of bisoprolol and hydrochlorothiazide in human plasma by HPLC coupled with tandem mass spectrometry.
Tutunji MF, Ibrahim HM, Khabbas MH, Tutunji LF. Tutunji MF, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Jun 1;877(16-17):1689-97. doi: 10.1016/j.jchromb.2009.04.021. Epub 2009 Apr 18. J Chromatogr B Analyt Technol Biomed Life Sci. 2009. PMID: 19427275
Linearity was demonstrated over the concentration range 0.10-30.0 (ng/mL) for bisoprolol and 1.00-80.00 ng/mL for hydrochlorothiazide. The limits of detection were 0.100 (ng/mL) for bisoprolol and 1.00 (ng/mL) for hydrochlorothiazide. The validated met …
Linearity was demonstrated over the concentration range 0.10-30.0 (ng/mL) for bisoprolol and 1.00-80.00 ng/mL for hydrochlorothiaz …
Short-term electrophysiological effects of losartan, bisoprolol, amlodipine, and hydrochlorothiazide in hypertensive men.
Porthan K, Viitasalo M, Hiltunen TP, Vaananen H, Dabek J, Suonsyrja T, Hannila-Handelberg T, Virolainen J, Nieminen MS, Toivonen L, Kontula K, Oikarinen L. Porthan K, et al. Ann Med. 2009;41(1):29-37. doi: 10.1080/07853890802195211. Ann Med. 2009. PMID: 18608135 Clinical Trial.
METHODS: A total of 183 hypertensive men received for 4 weeks drugs (losartan 50 mg, bisoprolol 5 mg, amlodipine 5 mg, hydrochlorothiazide (HCTZ) 25 mg) in a randomized order, separated by 4-week placebo periods. ...Amlodipine had no repolarization effects, whereas …
METHODS: A total of 183 hypertensive men received for 4 weeks drugs (losartan 50 mg, bisoprolol 5 mg, amlodipine 5 mg, hydrochloro …
118 results