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Page 1
A clinical trial evaluating the 24-hour effects of bisoprolol/hydrochlorothiazide 5 mg/6.25 mg combination in patients with mild to moderate hypertension.
Lewin AJ, Lueg MC, Targum S, Cardenas P. Lewin AJ, et al. Clin Cardiol. 1993 Oct;16(10):732-6. doi: 10.1002/clc.4960161009. Clin Cardiol. 1993. PMID: 8222387 Free article. Clinical Trial.
This is the first study to demonstrate the 24-h effectiveness of the bisoprolol/hydrochlorothiazide 5 mg/6.25 mg combination, using 24-h ambulatory BP monitoring. In addition, antihypertensive therapy with low doses of bisoprolol/hydrochlorothiazide in …
This is the first study to demonstrate the 24-h effectiveness of the bisoprolol/hydrochlorothiazide 5 mg/6.25 mg combination, …
Clinical results with bisoprolol 2.5 mg/hydrochlorothiazide 6.25 mg combination in systolic hypertension in the elderly.
Benetos A, Adamopoulos C, Argyriadis P, Bean K, Consoli S, Safar M. Benetos A, et al. J Hypertens Suppl. 2002 Feb;20(1):S21-5. J Hypertens Suppl. 2002. PMID: 11996196 Review.
A randomized, multicentre, double-blind, parallel group study was conducted to compare the efficacy and safety of bisoprolol 2.5 mg/hydrochlorothiazide 6.25 mg (biso 2.5/HCTZ 6.25) (n = 84) versus amlodipine 5 mg (n = 80) in subjects over 60years of age with isolate …
A randomized, multicentre, double-blind, parallel group study was conducted to compare the efficacy and safety of bisoprolol 2.5 mg/ …
A multifactorial trial design to assess combination therapy in hypertension. Treatment with bisoprolol and hydrochlorothiazide.
Frishman WH, Bryzinski BS, Coulson LR, DeQuattro VL, Vlachakis ND, Mroczek WJ, Dukart G, Goldberg JD, Alemayehu D, Koury K. Frishman WH, et al. Arch Intern Med. 1994 Jul 11;154(13):1461-8. Arch Intern Med. 1994. PMID: 8018001 Clinical Trial.
In consultation with the Cardio-Renal Division of the Food and Drug Administration, we conducted a randomized, double-blind, placebo-controlled, 3 x 4 factorial trial of bisoprolol, a beta 1-selective adrenergic blocking agent, and hydrochlorothiazide. METHODS: A to …
In consultation with the Cardio-Renal Division of the Food and Drug Administration, we conducted a randomized, double-blind, placebo-control …
[The clinical efficiency and safety of bisoprolol hydrochlorothiazide in patients with mild to moderate essential hypertension].
Jiang H, Ke YN; Lodoz Working Group. Jiang H, et al. Zhonghua Xin Xue Guan Bing Za Zhi. 2006 Jul;34(7):605-8. Zhonghua Xin Xue Guan Bing Za Zhi. 2006. PMID: 17081362 Clinical Trial. Chinese.
OBJECTIVE: To investigate the efficacy and safety of bisoprolol/hydrochlorothiazide (Lodoz) in patients with mild and moderate essential hypertension. ...
OBJECTIVE: To investigate the efficacy and safety of bisoprolol/hydrochlorothiazide (Lodoz) in patients with mild and moderate …
[Efficacy and tolerance of the bisoprolol/hydrochlorothiazide combination in arterial hypertension].
Luna RL, Oigman W, Ramirez JA, Mion D, Batlouni M, da Rocha JC, Feitosa GS, Castro I, Chaves Júnior Hde C, God EM, Maia LN, Ortega KC, Raineri AM. Luna RL, et al. Arq Bras Cardiol. 1998 Oct;71(4):601-8. doi: 10.1590/s0066-782x1998001000008. Arq Bras Cardiol. 1998. PMID: 10347937 Clinical Trial. Portuguese.
PURPOSE: Multicenter, open and non-controlled study to evaluated the efficacy and the tolerability of a low-dose combination of two anti-hypertensive agents: a cardioselective beta-blocker, bisoprolol (2.5 and 5.0 mg) with 6.25 mg of hydrochlorothiazide. METHODS: On …
PURPOSE: Multicenter, open and non-controlled study to evaluated the efficacy and the tolerability of a low-dose combination of two anti-hyp …
Efficacy, safety, and effects on quality of life of bisoprolol/hydrochlorothiazide versus amlodipine in elderly patients with systolic hypertension.
Benetos A, Consoli S, Safavian A, Dubanchet A, Safar M. Benetos A, et al. Am Heart J. 2000 Oct;140(4):E11. doi: 10.1067/mhj.2000.108834. Am Heart J. 2000. PMID: 11011336 Clinical Trial.
A randomized, multicenter, double-blind, parallel group study was conducted to compare the efficacy and safety of bisoprolol 2.5 mg/hydrochlorothiazide 6.25 mg (n = 84) to amlodipine 5 mg (n = 80) in isolated systolic hypertension in patients older than 60 years. .. …
A randomized, multicenter, double-blind, parallel group study was conducted to compare the efficacy and safety of bisoprolol 2.5 mg/ …
Short-term electrophysiological effects of losartan, bisoprolol, amlodipine, and hydrochlorothiazide in hypertensive men.
Porthan K, Viitasalo M, Hiltunen TP, Vaananen H, Dabek J, Suonsyrja T, Hannila-Handelberg T, Virolainen J, Nieminen MS, Toivonen L, Kontula K, Oikarinen L. Porthan K, et al. Ann Med. 2009;41(1):29-37. doi: 10.1080/07853890802195211. Ann Med. 2009. PMID: 18608135 Clinical Trial.
METHODS: A total of 183 hypertensive men received for 4 weeks drugs (losartan 50 mg, bisoprolol 5 mg, amlodipine 5 mg, hydrochlorothiazide (HCTZ) 25 mg) in a randomized order, separated by 4-week placebo periods. ...Amlodipine had no repolarization effects, whereas …
METHODS: A total of 183 hypertensive men received for 4 weeks drugs (losartan 50 mg, bisoprolol 5 mg, amlodipine 5 mg, hydrochloro …
Bioequivalence study of 2 formulations of film-coated tablets containing a fixed dose combination of bisoprolol fumarate 5 mg and hydrochlorothiazide 6.25 mg in healthy subjects.
Tjandrawinata RR, Setiawati E, Yunaidi DA, Santoso ID, Setiawati A, Susanto LW. Tjandrawinata RR, et al. Drug Res (Stuttg). 2013 May;63(5):243-9. doi: 10.1055/s-0033-1334922. Epub 2013 Mar 28. Drug Res (Stuttg). 2013. PMID: 23539427 Clinical Trial.
BACKGROUND: The present study was conducted to compare the bioavailability of 2 formulations of fixed-dose combination of bisoprolol fumarate 5 mg and hydrochlorotiazide (HCT) 6.25 mg film-coated tablet (test and reference formulations). ...The differences between the test …
BACKGROUND: The present study was conducted to compare the bioavailability of 2 formulations of fixed-dose combination of bisoprolol …
First-line therapy option with low-dose bisoprolol fumarate and low-dose hydrochlorothiazide in patients with stage I and stage II systemic hypertension.
Frishman WH, Burris JF, Mroczek WJ, Weir MR, Alemayehu D, Simon JS, Chen SY, Bryzinski BS. Frishman WH, et al. J Clin Pharmacol. 1995 Feb;35(2):182-8. doi: 10.1002/j.1552-4604.1995.tb05009.x. J Clin Pharmacol. 1995. PMID: 7751430 Clinical Trial.
This 30-center, randomized, double-blind, placebo-controlled, parallel-group study was designed to (1) establish that 6.25 mg of hydrochlorothiazide (HCTZ) given once daily with 5 mg of bisoprolol fumarate can contribute to antihypertensive effectiveness in patients …
This 30-center, randomized, double-blind, placebo-controlled, parallel-group study was designed to (1) establish that 6.25 mg of hydrochl …
Pharmacokinetic and dynamic interactions of the angiotensin-converting enzyme inhibitor imidapril with hydrochlorothiazide, bisoprolol and nilvadipine.
Breithaupt-Grögler K, Ungethüm W, Meurer-Witt B, Belz GG. Breithaupt-Grögler K, et al. Eur J Clin Pharmacol. 2001 Jul;57(4):275-84. doi: 10.1007/s002280100323. Eur J Clin Pharmacol. 2001. PMID: 11549204 Clinical Trial.
METHODS: In three separate, double-blind, placebo-controlled, four-way cross-over studies in healthy volunteers (n = 16 each), single oral doses of imidapril 10 mg (I), hydrochlorothiazide 12.5 mg (H), bisoprolol 5 mg (B) and nilvadipine 8 mg (N) were administered a …
METHODS: In three separate, double-blind, placebo-controlled, four-way cross-over studies in healthy volunteers (n = 16 each), single oral d …
41 results