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Year Number of Results
1979 1
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2005 1
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2017 2
2018 1
2020 1
2021 1
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Page 1
Safety Profile of Cough and Cold Medication Use in Pediatrics.
Green JL, Wang GS, Reynolds KM, Banner W, Bond GR, Kauffman RE, Palmer RB, Paul IM, Dart RC. Green JL, et al. Pediatrics. 2017 Jun;139(6):e20163070. doi: 10.1542/peds.2016-3070. Epub 2017 May 4. Pediatrics. 2017. PMID: 28562262
METHODS: Cases with adverse events (AEs) after ingestion of at least 1 index CCM ingredient (brompheniramine, chlorpheniramine, dextromethorphan, diphenhydramine, doxylamine, guaifenesin, phenylephrine, and pseudoephedrine) in children <12 years of age wer …
METHODS: Cases with adverse events (AEs) after ingestion of at least 1 index CCM ingredient (brompheniramine, chlorpheniramine, de …
Ion-pair reversed-phase high-pressure liquid chromatography of cough-cold syrups I: pseudoephedrine hydrochloride, brompheniramine maleate, and dextromethorphan hydrobromide.
Chao MK, Holcomb IJ, Fusari SA. Chao MK, et al. J Pharm Sci. 1979 Nov;68(11):1463-4. doi: 10.1002/jps.2600681137. J Pharm Sci. 1979. PMID: 512904
Pseudoephedrine hydrochloride (I), brompheniramine maleate (II), and dextromethorphan hydrobromide (III) in a cough-cold sytup were separated and determined by ion-pair reversed-phase high-pressure liquid chromatography. ...
Pseudoephedrine hydrochloride (I), brompheniramine maleate (II), and dextromethorphan hydrobromide (III) in a cough-col …
Possible role of pseudoephedrine and other over-the-counter cold medications in the deaths of very young children.
Wingert WE, Mundy LA, Collins GL, Chmara ES. Wingert WE, et al. J Forensic Sci. 2007 Mar;52(2):487-90. doi: 10.1111/j.1556-4029.2007.00391.x. J Forensic Sci. 2007. PMID: 17316256
The Philadelphia Medical Examiners Office has reported a series of 15 deaths between February 1999 and June 2005 of infants and toddlers 16 months and younger in which drugs commonly found in over-the-counter (OTC) cold medications were present. A total of 10 different drugs were …
The Philadelphia Medical Examiners Office has reported a series of 15 deaths between February 1999 and June 2005 of infants and toddlers 16 …
Assessment of Pharmacologic Ingredients in Common Over-the-Counter Sinonasal Medications.
McCoul ED. McCoul ED. JAMA Otolaryngol Head Neck Surg. 2020 Sep 1;146(9):810-815. doi: 10.1001/jamaoto.2020.1836. JAMA Otolaryngol Head Neck Surg. 2020. PMID: 32672802 Free PMC article.
Only 8 unique nonanalgesic ingredients were identified among these products, with many products sold under the same brand name and with the same active ingredient. Phenylephrine hydrochloride, dextromethorphan hydrobromide, pseudoephedrine hydrochloride, guaifenesin …
Only 8 unique nonanalgesic ingredients were identified among these products, with many products sold under the same brand name and with the …
Cough and cold medication use by US children, 1999-2006: results from the slone survey.
Vernacchio L, Kelly JP, Kaufman DW, Mitchell AA. Vernacchio L, et al. Pediatrics. 2008 Aug;122(2):e323-9. doi: 10.1542/peds.2008-0498. Pediatrics. 2008. PMID: 18676518
RESULTS: In a given week, a cough and cold medication was used by 10.1% of US children. Exposure was highest to decongestants (6.3%; mostly pseudoephedrine) and first-generation antihistamines (6.3%; most common were chlorpheniramine, diphenhydramine, and brompheniramin …
RESULTS: In a given week, a cough and cold medication was used by 10.1% of US children. Exposure was highest to decongestants (6.3%; mostly …
Fatal cold medication intoxication in an infant.
Boland DM, Rein J, Lew EO, Hearn WL. Boland DM, et al. J Anal Toxicol. 2003 Oct;27(7):523-6. doi: 10.1093/jat/27.7.523. J Anal Toxicol. 2003. PMID: 14607011
The case history and toxicological findings of an infant fatality involving pseudoephedrine, brompheniramine, and dextromethorphan are presented. ...Brompheniramine and dextromethorphan were 0.40 mg/L and 0.50 mg/L, respectively, in the blood sa …
The case history and toxicological findings of an infant fatality involving pseudoephedrine, brompheniramine, and dextromet …
Reduction of interferences in the analysis of Children's Dimetapp using ultraviolet spectroscopy data and target factor analysis.
Msimanga HZ, Lam TTH, Latinwo N, Song MK, Tavakoli N. Msimanga HZ, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2018 Mar 5;192:159-167. doi: 10.1016/j.saa.2017.11.012. Epub 2017 Nov 3. Spectrochim Acta A Mol Biomol Spectrosc. 2018. PMID: 29128750
Before including interferences, the following results were obtained: brompheniramine maleate=481.3mgL(-1)134% RE; phenylephrine hydrogen chloride=1041mgL(-1)107% RE; dextromethorphan hydrogen bromide=1571mgL(-1)107% RE, where % RE=percent relative error based on the …
Before including interferences, the following results were obtained: brompheniramine maleate=481.3mgL(-1)134% RE; phenylephrine hydro …
Over-the-counter cold medications-postmortem findings in infants and the relationship to cause of death.
Marinetti L, Lehman L, Casto B, Harshbarger K, Kubiczek P, Davis J. Marinetti L, et al. J Anal Toxicol. 2005 Oct;29(7):738-43. doi: 10.1093/jat/29.7.738. J Anal Toxicol. 2005. PMID: 16419411
The Montgomery County Coroner's Office has encountered a series of 10 infant deaths over an 8-month period in infants under 12 months old with toxicology findings that include a variety of drugs commonly found in over-the-counter (OTC) cold medications. The drugs detected were ep …
The Montgomery County Coroner's Office has encountered a series of 10 infant deaths over an 8-month period in infants under 12 months old wi …