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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 1
1985 2
1986 5
1987 3
1988 8
1989 1
1990 3
1991 1
1993 2
1996 2
1999 1
2000 1
2001 1
2005 3
2006 1
2007 2
2008 1
2009 2
2012 1
2014 1
2021 1
2022 0
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42 results
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Page 1
Comparison of three-day butoconazole treatment with seven-day miconazole treatment for vulvovaginal candidiasis.
Kaufman RH, Henzl MR, Brown D Jr, Horner DS, Krauss RH, Mehlisch DR, Moore DE, Prentice RL. Kaufman RH, et al. J Reprod Med. 1989 Jul;34(7):479-83. J Reprod Med. 1989. PMID: 2671362 Clinical Trial.
Eight to ten days after treatment completion, 88% of the butoconazole-treated patients and 91% of the miconazole-treated patients were Candida negative; 80% of the butoconazole-treated patients and 82% of the miconazole-treated patients were considered clinically cu …
Eight to ten days after treatment completion, 88% of the butoconazole-treated patients and 91% of the miconazole-treated patients wer …
Butoconazole nitrate 2% for vulvovaginal candidiasis. New, single-dose vaginal cream formulation vs. seven-day treatment with miconazole nitrate. Gynazole 1 Study Group.
Brown D, Henzl MR, Kaufman RH. Brown D, et al. J Reprod Med. 1999 Nov;44(11):933-8. J Reprod Med. 1999. PMID: 10589403 Clinical Trial.
OBJECTIVE: To compare the safety and efficacy of a single vaginal dose of a butoconazole nitrate 2% bioadhesive, sustained-release cream* (butoconazole 1-BSR) with a seven-day schedule of miconazole nitrate vaginal cream 2% (miconazole 7). ...A total of 205 patients …
OBJECTIVE: To compare the safety and efficacy of a single vaginal dose of a butoconazole nitrate 2% bioadhesive, sustained-release cr …
An evaluation of butoconazole nitrate 2% site release vaginal cream (Gynazole-1) compared to fluconazole 150 mg tablets (Diflucan) in the time to relief of symptoms in patients with vulvovaginal candidiasis.
Seidman LS, Skokos CK. Seidman LS, et al. Infect Dis Obstet Gynecol. 2005 Dec;13(4):197-206. doi: 10.1080/10647440500240615. Infect Dis Obstet Gynecol. 2005. PMID: 16338779 Free PMC article. Clinical Trial.

RESULTS: The median time to first relief of symptoms occurred at 17.5 h for butoconazole patients as compared to 22.9 h for fluconazole patients (p < 0.001). The time at which 75% of patients experienced first relief of symptoms was 24.5 h versus 46.3 h for butoconaz

RESULTS: The median time to first relief of symptoms occurred at 17.5 h for butoconazole patients as compared to 22.9 h for fluconazo …
Butoconazole nitrate.
Tatum DM, Eggleston M. Tatum DM, et al. Infect Control Hosp Epidemiol. 1988 Mar;9(3):122-4. doi: 10.1086/645809. Infect Control Hosp Epidemiol. 1988. PMID: 3280665 Clinical Trial. No abstract available.
Treatment of recurrent vulvo-vaginal candidiasis with sustained-released butoconazole pessary.
Heng LZ, Chen Y, Tan TC. Heng LZ, et al. Singapore Med J. 2012 Dec;53(12):e269-71. Singapore Med J. 2012. PMID: 23268172 Free article.
This could be due to patient factors, drug application (such as leakage) or dosing factors. A sustained-release (SR) bioadhesive vaginal cream (2% butoconazole nitrate) has incorporated VagiSite technology, a topical drug delivery system that allows SR of the drug. We desc …
This could be due to patient factors, drug application (such as leakage) or dosing factors. A sustained-release (SR) bioadhesive vaginal cre …
Butoconazole and miconazole in treating vaginal candidiasis.
Bradbeer CS, Mayhew SR, Barlow D. Bradbeer CS, et al. Genitourin Med. 1985 Aug;61(4):270-2. doi: 10.1136/sti.61.4.270. Genitourin Med. 1985. PMID: 3894216 Free PMC article. Clinical Trial.
In a single blind trial, a three day course of butoconazole nitrate cream was compared with a seven day course of miconazole nitrate cream, both applied intravaginally, in treating vaginal candidiasis. They were equally effective. The cure rate for patients treated with …
In a single blind trial, a three day course of butoconazole nitrate cream was compared with a seven day course of miconazole nitrate …
Development of a liquid chromatography-tandem mass spectrometry method for determination of butoconazole nitrate in human plasma and its application to a pharmacokinetic study.
Jia MM, Zhou Y, He XM, Wu YL, Li HQ, Chen H, Li WY. Jia MM, et al. J Huazhong Univ Sci Technolog Med Sci. 2014 Jun;34(3):431-436. doi: 10.1007/s11596-014-1296-y. Epub 2014 Jun 18. J Huazhong Univ Sci Technolog Med Sci. 2014. PMID: 24939312
The compounds were eluted isocratically on an Inertsil ODS-SP column (100 mm2.1 mm, 3 mum), ionized using a positive ion atmospheric pressure electrospray ionization source and analyzed using multiple reaction monitoring (MRM) mode. The ion transitions monitored were m/z 412.8165 …
The compounds were eluted isocratically on an Inertsil ODS-SP column (100 mm2.1 mm, 3 mum), ionized using a positive ion atmospheric pressur …
Effect of butoconazole nitrate 2% vaginal cream and miconazole nitrate 2% vaginal cream treatments in patients with vulvovaginal candidiasis.
Lappin MA, Brooker DC, Francisco CA, Dorfman J. Lappin MA, et al. Infect Dis Obstet Gynecol. 1996;4(6):323-8. doi: 10.1155/S1064744996000658. Infect Dis Obstet Gynecol. 1996. PMID: 18476119 Free PMC article.
In a multicenter, randomized, invesgtigator-blind, parallel study, 398 patients were dispensed topical butoconazole nitrate 2% cream for 3 days (n = 199) or miconazole nitrate 2% cream for 7 days (n = 199) for vaginal use. ...Therapeutic cure rates were 57.8% …
In a multicenter, randomized, invesgtigator-blind, parallel study, 398 patients were dispensed topical butoconazole nitrate 2% cream …
A new vaginal antifungal agent--butoconazole nitrate.
Jacobson JB, Hajman AJ, Wiese J, Gandrup P, Forsström S. Jacobson JB, et al. Acta Obstet Gynecol Scand. 1985;64(3):241-4. doi: 10.3109/00016348509155121. Acta Obstet Gynecol Scand. 1985. PMID: 3893024 Clinical Trial.
The continuously increasing incidence of vulvovaginal candidiasis necessitated a search for novel therapeutic modalities. Butoconazole nitrate (BN) a new imidazole, has been singled out for clinical studies since, in experimental vaginal candidiasis, it proved more …
The continuously increasing incidence of vulvovaginal candidiasis necessitated a search for novel therapeutic modalities. Butocona
42 results