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Page 1
Butenafine.
McNeely W, Spencer CM. McNeely W, et al. Drugs. 1998 Mar;55(3):405-12; discussion 413. doi: 10.2165/00003495-199855030-00006. Drugs. 1998. PMID: 9530545 Review.
Butenafine is a new antifungal agent with primary fungicidal activity against dermatophytes such as Trichophyton mentagrophytes, Microsporum canis and Trichophyton rubrum which cause tinea infections. 14C-labelled butenafine (approximately 30 micrograms/g tissue) wa …
Butenafine is a new antifungal agent with primary fungicidal activity against dermatophytes such as Trichophyton mentagrophytes, Micr …
Butenafine and superficial mycoses: current status.
Singal A. Singal A. Expert Opin Drug Metab Toxicol. 2008 Jul;4(7):999-1005. doi: 10.1517/17425255.4.7.999. Expert Opin Drug Metab Toxicol. 2008. PMID: 18624686 Review.
BACKGROUND: Butenafine hydrochloride, a benzylamine derivative, exhibits potent fungicidal activity particularly against dermatophytes, aspergilli, dimorphic and dematiaceous fungi. OBJECTIVE: To review pharmacokinetics, mechanism of actions and clinical efficacy of but …
BACKGROUND: Butenafine hydrochloride, a benzylamine derivative, exhibits potent fungicidal activity particularly against dermatophyte …
Butenafine hydrochloride: for the treatment of interdigital tinea pedis.
Syed TA, Maibach HI. Syed TA, et al. Expert Opin Pharmacother. 2000 Mar;1(3):467-73. doi: 10.1517/14656566.1.3.467. Expert Opin Pharmacother. 2000. PMID: 11249531 Review.
In controlled clinical trials when applied topically, butenafine appears to be well tolerated with a subjective mild burning sensation at the application site. There were no withdrawals from the study. Butenafine is sparingly soluble in water but readily soluble in …
In controlled clinical trials when applied topically, butenafine appears to be well tolerated with a subjective mild burning sensatio …
Fungal toenail infections.
Ferrari J. Ferrari J. BMJ Clin Evid. 2014 Mar 13;2014:1715. BMJ Clin Evid. 2014. PMID: 24625577 Free PMC article. Review.
CONCLUSIONS: In this systematic review, we present information relating to the effectiveness and safety of the following interventions: amorolfine, butenafine, ciclopirox, fluconazole, itraconazole, terbinafine, tioconazole, and topical ketoconazole....
CONCLUSIONS: In this systematic review, we present information relating to the effectiveness and safety of the following interventions: amor …
Six novel antimycotics.
Rubin AI, Bagheri B, Scher RK. Rubin AI, et al. Am J Clin Dermatol. 2002;3(2):71-81. doi: 10.2165/00128071-200203020-00001. Am J Clin Dermatol. 2002. PMID: 11893219 Review.
Butenafine has a potent fungicidal action and the drug has been shown to be effective in multiple clinical trials in patients with tinea pedis, tinea corporis and tinea cruris. Butenafine has also been reported to exert an anti-inflammatory action after topical appl …
Butenafine has a potent fungicidal action and the drug has been shown to be effective in multiple clinical trials in patients with ti …
[Activity of butenafine against ocular pathogenic filamentous fungi in vitro].
Xu Y, Pang GR, Zhao DQ, Gao CW, Zhou LT, Sun ST, Wang BL, Chen ZJ. Xu Y, et al. Zhonghua Yan Ke Za Zhi. 2010 Jan;46(1):38-42. Zhonghua Yan Ke Za Zhi. 2010. PMID: 20388321 Chinese.
OBJECTIVE: To investigate antifungal activity of butenafine in comparison with that of natamycin, amphotericin B and fluconazole against ocular pathogenic filamentous fungi in vitro. ...Final concentration ranged from 0.008 to 16.000 mg/L for butenafine, from 0.031 …
OBJECTIVE: To investigate antifungal activity of butenafine in comparison with that of natamycin, amphotericin B and fluconazole agai …
Fungal toenail infections.
Ferrari J. Ferrari J. BMJ Clin Evid. 2008 Dec 15;2008:1715. BMJ Clin Evid. 2008. PMID: 19445781 Free PMC article. Review.
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: amorolfine, butenafine, ciclopirox, fluconazole, griseofulvin, itraconazole, ketoconazole, mechanical debridement, terbinafine, and tiocon …
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: amoro …
Formulation and evaluation of butenafine loaded PLGA-nanoparticulate laden chitosan nano gel.
Alshehri S, Imam SS. Alshehri S, et al. Drug Deliv. 2021 Dec;28(1):2348-2360. doi: 10.1080/10717544.2021.1995078. Drug Deliv. 2021. PMID: 34747275 Free PMC article.
The present research work is designed to prepare and optimize butenafine (BT) loaded poly lactic co glycolic acid (PLGA) nanoparticles (BT-NPs). BT-NPs were prepared by emulsification probe sonication method using PLGA (A), PVA (B) as polymer and stabilizer, respectively. …
The present research work is designed to prepare and optimize butenafine (BT) loaded poly lactic co glycolic acid (PLGA) nanoparticle …
Butenafine hydrochloride (Mentax) cream for the treatment of hyperkeratotic type tinea pedis and its transfer into the horny layer, with or without concomitant application of 20% urea ointment (Keratinamin).
Tanuma H, Doi M, Ohta Y, Abe M, Kume H, Mukai H, Katsuoka K. Tanuma H, et al. Mycoses. 2001;44(7-8):287-99. doi: 10.1046/j.0933-7407.2001.00653.x. Mycoses. 2001. PMID: 11714064
Forty-five patients were divided into two groups: group I, 23 patients, treated with butenafine hydrochloride (Mentax) cream alone, and group II, 22 patients, treated with butenafine hydrochloride and 20% urea ointment (Keratinamin) to evaluate the usefulness of the …
Forty-five patients were divided into two groups: group I, 23 patients, treated with butenafine hydrochloride (Mentax) cream alone, a …
Two mechanisms of butenafine action in Candida albicans.
Iwatani W, Arika T, Yamaguchi H. Iwatani W, et al. Antimicrob Agents Chemother. 1993 Apr;37(4):785-8. doi: 10.1128/AAC.37.4.785. Antimicrob Agents Chemother. 1993. PMID: 8494375 Free PMC article.
Butenafine completely inhibited the growth of a test strain of C. albicans at 25 micrograms/ml and was cidal at 50 micrograms/ml. ...Butenafine, but not tolnaftate, induced the release of appreciable amounts of Pi from C. albicans cells at 12.5 micrograms/ml. ...
Butenafine completely inhibited the growth of a test strain of C. albicans at 25 micrograms/ml and was cidal at 50 micrograms/ml. ... …
74 results