Selectivity of plasma membrane calcium ATPase (PMCA)-mediated extrusion of toxic divalent cations in vitro and in cultured cells.
Ferreira-Gomes MS, Mangialavori IC, Ontiveros MQ, Rinaldi DE, Martiarena J, Verstraeten SV, Rossi JPFC.
Ferreira-Gomes MS, et al.
Arch Toxicol. 2018 Jan;92(1):273-288. doi: 10.1007/s00204-017-2031-9. Epub 2017 Jul 18.
Arch Toxicol. 2018.
PMID: 28721440
Among other mechanisms, these cations may affect the functionality of certain Ca(2+)-binding proteins and/or Ca(2+) pumps. The plasma membrane calcium pump (PMCA) maintains Ca(2+) homeostasis in eukaryotic cells by mediating the efflux of this cation in a process coupled t …
Among other mechanisms, these cations may affect the functionality of certain Ca(2+)-binding proteins and/or Ca(2+) pumps. The plasma membra …