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Year Number of Results
1990 3
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1992 2
1993 1
1995 5
1996 2
1997 5
1998 3
1999 3
2000 11
2002 1
2003 1
2004 4
2005 2
2006 5
2007 2
2008 1
2011 1
2012 2
2013 1
2014 1
2015 1
2016 2
2017 1
2021 2
2023 1
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60 results
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Page 1
Antibiotics-First Versus Surgery for Appendicitis: A US Pilot Randomized Controlled Trial Allowing Outpatient Antibiotic Management.
Talan DA, Saltzman DJ, Mower WR, Krishnadasan A, Jude CM, Amii R, DeUgarte DA, Wu JX, Pathmarajah K, Morim A, Moran GJ; Olive View–UCLA Appendicitis Study Group. Talan DA, et al. Ann Emerg Med. 2017 Jul;70(1):1-11.e9. doi: 10.1016/j.annemergmed.2016.08.446. Epub 2016 Dec 11. Ann Emerg Med. 2017. PMID: 27974169 Free PMC article. Clinical Trial.
METHODS: Patients aged 5 years or older with uncomplicated appendicitis at 1 US hospital were randomized to appendectomy or intravenous ertapenem greater than or equal to 48 hours and oral cefdinir and metronidazole. Stable antibiotics-first-treated participants older than …
METHODS: Patients aged 5 years or older with uncomplicated appendicitis at 1 US hospital were randomized to appendectomy or intravenous erta …
Comparison of cefdinir and penicillin for the treatment of streptococcal pharyngitis. Cefdinir Pharyngitis Study Group.
Nemeth MA, McCarty J, Gooch WM 3rd, Henry D, Keyserling CH, Tack KJ. Nemeth MA, et al. Clin Ther. 1999 Nov;21(11):1873-81. doi: 10.1016/s0149-2918(00)86735-1. Clin Ther. 1999. PMID: 10890259 Clinical Trial.
The eradication rates 4 to 9 days after completion of therapy were 91.4% in the cefdinir QD group, 91.7% in the cefdinir BID group, and 83.4% in the penicillin group (P = 0.02 for cefdinir QD vs penicillin, P = 0.01 for cefdinir BID vs penicillin, P = …
The eradication rates 4 to 9 days after completion of therapy were 91.4% in the cefdinir QD group, 91.7% in the cefdinir BID g …
Clinical and economic considerations in the use of third-generation oral cephalosporins.
Chambers ST, Murdoch DR, Pearce MJ. Chambers ST, et al. Pharmacoeconomics. 1995 May;7(5):416-27. doi: 10.2165/00019053-199507050-00006. Pharmacoeconomics. 1995. PMID: 10155329 Review.
A number of oral third-generation cephalosporins (cefixime, cefetamet pivoxil, ceftibuten and cefpodoxime proxetil) have been widely trialled and are becoming available. In addition, cefdinir may also be marketed. Compared with first- and second-generation agents, the oral …
A number of oral third-generation cephalosporins (cefixime, cefetamet pivoxil, ceftibuten and cefpodoxime proxetil) have been widely trialle …
[Pharmacokinetic and clinical studies of cefdinir in the pediatric field. Pediatric Study Group of Cefdinir].
Fujii R, Yoshioka H, Fujita K, Sakata H, Nire H, Iseki K, Murono K, Takahashi Y, Wagatsuma Y, Fukushima N, et al. Fujii R, et al. Jpn J Antibiot. 1991 Oct;44(10):1168-91. Jpn J Antibiot. 1991. PMID: 1762172 Clinical Trial. Japanese.
We studied pharmacokinetics and clinical effects of 5% and 10% fine granules of cefdinir (FK 482, CFDN), a new oral cephalosporin, in the pediatric field and the following results were obtained. 1. ...
We studied pharmacokinetics and clinical effects of 5% and 10% fine granules of cefdinir (FK 482, CFDN), a new oral cephalosporin, in …
Comparison of cefdinir and penicillin for the treatment of pediatric streptococcal pharyngitis.
Nemeth MA, Gooch WM 3rd, Hedrick J, Slosberg E, Keyserling CH, Tack KJ. Nemeth MA, et al. Clin Ther. 1999 Sep;21(9):1525-32. doi: 10.1016/s0149-2918(00)80007-7. Clin Ther. 1999. PMID: 10509847 Clinical Trial.
Clinical cure rates were 97.4%, 96.0%, and 86.3% for the cefdinir QD, cefdinir BID, and penicillin groups, respectively (CI 6.1%-15.9%, P = 0.001 for cefdinir QD vs penicillin; CI 4.6%-14.8%, P = 0.001 for cefdinir BID vs penicillin). Adverse reactions …
Clinical cure rates were 97.4%, 96.0%, and 86.3% for the cefdinir QD, cefdinir BID, and penicillin groups, respectively (CI 6. …
Cefdinir versus cephalexin for the treatment of skin and skin-structure infections. The Cefdinir Adult Skin Infection Study Group.
Tack KJ, Littlejohn TW, Mailloux G, Wolf MM, Keyserling CH. Tack KJ, et al. Clin Ther. 1998 Mar-Apr;20(2):244-56. doi: 10.1016/s0149-2918(98)80088-x. Clin Ther. 1998. PMID: 9589816 Clinical Trial.
Cefdinir taken BID was as effective as cephalexin taken QID in the treatment of mild-to-moderate SSSIs and was well tolerated by most patients. The increased antibacterial activity of cefdinir must be balanced against the higher rate of diarrhea seen in patients tre …
Cefdinir taken BID was as effective as cephalexin taken QID in the treatment of mild-to-moderate SSSIs and was well tolerated by most …
Comparative effectiveness and safety of cefdinir and amoxicillin-clavulanate in treatment of acute community-acquired bacterial sinusitis. Cefdinir Sinusitis Study Group.
Gwaltney JM Jr, Savolainen S, Rivas P, Schenk P, Scheld WM, Sydnor A, Keyserling C, Leigh A, Tack KJ. Gwaltney JM Jr, et al. Antimicrob Agents Chemother. 1997 Jul;41(7):1517-20. doi: 10.1128/AAC.41.7.1517. Antimicrob Agents Chemother. 1997. PMID: 9210677 Free PMC article. Clinical Trial.
Cefdinir is an extended-spectrum oral cephalosporin that is active against pathogens commonly seen in acute community-acquired bacterial sinusitis (ACABS), including Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. ...The major side effect was m …
Cefdinir is an extended-spectrum oral cephalosporin that is active against pathogens commonly seen in acute community-acquired bacter …
Five-day twice daily cefdinir therapy for acute otitis media: microbiologic and clinical efficacy.
Block SL, Hedrick JA, Kratzer J, Nemeth MA, Tack KJ. Block SL, et al. Pediatr Infect Dis J. 2000 Dec;19(12 Suppl):S153-8. doi: 10.1097/00006454-200012001-00004. Pediatr Infect Dis J. 2000. PMID: 11144397 Clinical Trial.
OBJECTIVE: To examine the microbiologic and clinical efficacy of a 5-day course of cefdinir in the treatment of tympanocentesis-documented acute otitis media (AOM). ...Cefdinir should be considered a suitable second line antibiotic for AOM....
OBJECTIVE: To examine the microbiologic and clinical efficacy of a 5-day course of cefdinir in the treatment of tympanocentesis-docum …
Efficacy and safety of cefdinir in the treatment of maxillary sinusitis.
Steurer M, Schenk P. Steurer M, et al. Eur Arch Otorhinolaryngol. 2000;257(3):140-8. doi: 10.1007/s004050050211. Eur Arch Otorhinolaryngol. 2000. PMID: 10839487 Clinical Trial.
In this investigator-blinded multicenter phase III clinical study, 569 patients were randomly assigned to one of three treatment regimens: one daily dose of cefdinir 600 mg (OD), cefdinir 300 mg every 12 h (BD), and amox/clav 500/125 mg every 8 h. ...Present finding …
In this investigator-blinded multicenter phase III clinical study, 569 patients were randomly assigned to one of three treatment regimens: o …
[Pharmacokinetics and clinical effects of cefdinir 10% fine granules in pediatrics].
Motohiro T, Handa S, Yamada S, Oki S, Tsumura N, Yoshinaga Y, Sasaki H, Aramaki M, Oda K, Kawakami A, et al. Motohiro T, et al. Jpn J Antibiot. 1992 Jan;45(1):74-86. Jpn J Antibiot. 1992. PMID: 1495197 Clinical Trial. Japanese.
Cefdinir (CFDN), a newly developed oral cephalosporin in a 10% fine granular form, was administered to 8 children and concentrations of the drug in plasma and urine and urinary recovery rates of the drug were determined. ...
Cefdinir (CFDN), a newly developed oral cephalosporin in a 10% fine granular form, was administered to 8 children and concentrations …
60 results