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Xerostomia: an immunotherapy-related adverse effect in cancer patients.
Bustillos H, Indorf A, Alwan L, Thompson J, Jung L. Bustillos H, et al. Support Care Cancer. 2022 Feb;30(2):1681-1687. doi: 10.1007/s00520-021-06535-9. Epub 2021 Sep 25. Support Care Cancer. 2022. PMID: 34562169
RESULTS: Six patients with advanced solid tumors who received a PD-1 inhibitor or PD-1/CTLA-4 inhibitor combination therapy were evaluated. The median time to onset of xerostomia was 4.5 months overall, though symptoms developed sooner in patients who received IO as …
RESULTS: Six patients with advanced solid tumors who received a PD-1 inhibitor or PD-1/CTLA-4 inhibitor combination therapy we …
Risk of Parkinson disease in Sjögren syndrome administered ineffective immunosuppressant therapies: A nationwide population-based study.
Ju UH, Liu FC, Lin CS, Huang WY, Lin TY, Shen CH, Chou YC, Lin CL, Lin KT, Kao CH, Chen CH, Yang TY. Ju UH, et al. Medicine (Baltimore). 2019 Apr;98(14):e14984. doi: 10.1097/MD.0000000000014984. Medicine (Baltimore). 2019. PMID: 30946325 Free PMC article.
The cumulative incidence of PD was 1.95% higher in the SS cohort than in the non-SS cohort. The SS cohort had an elevated HR under medication use, namely cevimeline and pilocarpine (crude HR, 1.28), hydroxychloroquine (crude HR, 1.43; aHR, 1.46), and methylprednisol …
The cumulative incidence of PD was 1.95% higher in the SS cohort than in the non-SS cohort. The SS cohort had an elevated HR under me …