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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 2
1965 10
1966 32
1967 44
1968 53
1969 33
1970 32
1971 43
1972 38
1973 47
1974 38
1975 47
1976 29
1977 24
1978 27
1979 25
1980 11
1981 17
1982 14
1983 15
1984 13
1985 8
1986 13
1987 13
1988 14
1989 11
1990 11
1991 10
1992 8
1993 17
1994 12
1995 8
1996 19
1997 18
1998 18
1999 8
2000 10
2001 3
2002 8
2003 10
2004 12
2005 8
2006 5
2007 11
2008 4
2009 7
2010 4
2011 7
2012 1
2013 4
2014 5
2015 1
2016 4
2017 2
2018 5
2019 4
2020 3
2021 0
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892 results
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Page 1
Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine.
Kane J, Honigfeld G, Singer J, Meltzer H. Kane J, et al. Arch Gen Psychiatry. 1988 Sep;45(9):789-96. doi: 10.1001/archpsyc.1988.01800330013001. Arch Gen Psychiatry. 1988. PMID: 3046553 Clinical Trial.
This report describes a multicenter clinical trial to assess clozapine's efficacy in the treatment of patients who are refractory to neuroleptics. ...Patients whose condition remained unimproved were then randomly assigned, in a double-blind manner, to clozapine (up to 900 …
This report describes a multicenter clinical trial to assess clozapine's efficacy in the treatment of patients who are refractory to …
Double-blind comparative clinical trial of pimozide and chlorpromazine in mania. A test of the dopamine hypothesis.
Cookson J, Silverstone T, Wells B. Cookson J, et al. Acta Psychiatr Scand. 1981 Nov;64(5):381-97. doi: 10.1111/j.1600-0447.1981.tb00797.x. Acta Psychiatr Scand. 1981. PMID: 7051755 Clinical Trial.
Pimozide (PMZ), a relatively specific dopamine (DA) receptor blocking drug, was compared to chlorpromazine (CPZ) in a double-blind, between-patient clinical trial in mania. The trial lasted 14 days. Twenty-three patients who fulfilled Feighner's criteria for mania e …
Pimozide (PMZ), a relatively specific dopamine (DA) receptor blocking drug, was compared to chlorpromazine (CPZ) in a double-blind, b …
Clinical-pharmacological study with the two isomers (d-, l-) of fenfluramine and its comparison with chlorpromazine and d-amphetamine: blood levels, EEG mapping and safety evaluation.
Saletu B, Barbanoj MJ, Anderer P, Sieghart W, Grünberger J. Saletu B, et al. Methods Find Exp Clin Pharmacol. 1993 Jun;15(5):291-312. Methods Find Exp Clin Pharmacol. 1993. PMID: 8412414 Clinical Trial.
In a double-blind, placebo-controlled, crossover study, the blood levels and pharmacodynamic properties of single oral doses of 15 and 30 mg d-fenfluramine (d-FEN) and 30 mg l-fenfluramine (l-FEN) were investigated as compared with 50 mg chlorpromazine (CPZ) and 20 mg d-am …
In a double-blind, placebo-controlled, crossover study, the blood levels and pharmacodynamic properties of single oral doses of 15 and 30 mg …
Phenothiazine analgesia--fact or fantasy?
McGee JL, Alexander MR. McGee JL, et al. Am J Hosp Pharm. 1979 May;36(5):633-40. Am J Hosp Pharm. 1979. PMID: 36754 Review.
Promethazine, promazine and propiomazine were not found to possess analgesic or potentiating properties. One chlorpromazine study contained important design and reporting deficiencies which precluded a recommendation for use of chlorpromazine in the treatment of pai …
Promethazine, promazine and propiomazine were not found to possess analgesic or potentiating properties. One chlorpromazine study con …
A placebo-controlled clinical trial of remoxipride and chlorpromazine in newly admitted schizophrenic patients with acute exacerbation.
Chouinard G. Chouinard G. Acta Psychiatr Scand Suppl. 1990;358:111-9. doi: 10.1111/j.1600-0447.1990.tb05301.x. Acta Psychiatr Scand Suppl. 1990. PMID: 1978469 Clinical Trial.
Chlorpromazine was found to be significantly better than remoxipride on the dropout rate due to inefficacy, Clinical Global Impression (CGI) of severity of illness and Brief Psychiatric Rating Scale (BPRS). Chlorpromazine tended to be better than placebo on the drop
Chlorpromazine was found to be significantly better than remoxipride on the dropout rate due to inefficacy, Clinical Global Impressio
Neuroleptics antagonize nalbuphine antianalgesia.
Gear RW, Lee JS, Miaskowski C, Gordon NC, Paul SM, Levine JD. Gear RW, et al. J Pain. 2006 Mar;7(3):187-91. doi: 10.1016/j.jpain.2005.10.005. J Pain. 2006. PMID: 16516824 Clinical Trial.
To evaluate the role of sigma receptors in the sexually dimorphic antianalgesic effect of agonist-antagonist kappa opioids, 2 neuroleptics, haloperidol, a sigma receptor antagonist, and chlorpromazine, which has minimal effect at sigma receptors, were administered with the …
To evaluate the role of sigma receptors in the sexually dimorphic antianalgesic effect of agonist-antagonist kappa opioids, 2 neuroleptics, …
Mesoridazine and thioridazine: clinical effects and blood levels in refractory schizophrenics.
Vital-Herne J, Gerbino L, Kay SR, Katz IR, Opler LA. Vital-Herne J, et al. J Clin Psychiatry. 1986 Jul;47(7):375-9. J Clin Psychiatry. 1986. PMID: 2873133 Clinical Trial.
A higher neuroleptic blood level was achieved with mesoridazine or thioridazine at less than half the reference chlorpromazine dosage. Correlations between neuroleptic blood level and clinical response were positive for mesoridazine, negative for chlorpromazine, and …
A higher neuroleptic blood level was achieved with mesoridazine or thioridazine at less than half the reference chlorpromazine dosage …
Electroencephalographic and psychomotor effects of chlorpromazine and risperidone relative to placebo in normal healthy volunteers.
Hughes AM, Lynch P, Rhodes J, Ervine CM, Yates RA. Hughes AM, et al. Br J Clin Pharmacol. 1999 Sep;48(3):323-30. doi: 10.1046/j.1365-2125.1999.00021.x. Br J Clin Pharmacol. 1999. PMID: 10510142 Free PMC article. Clinical Trial.
On each trial day volunteers were dosed twice. Dose 1 consisting of either chlorpromazine 50 mg or placebo to chlorpromazine, and dose 2 either risperidone 2 mg or placebo to risperidone. The volunteers were randomized so that each received either chlorpromazine
On each trial day volunteers were dosed twice. Dose 1 consisting of either chlorpromazine 50 mg or placebo to chlorpromazine, …
Relationships between drug concentrations in serum and CSF, clinical effects and monoaminergic variables in schizophrenic patients treated with sulpiride or chlorpromazine.
Alfredsson G, Bjerkenstedt L, Edman G, Härnryd C, Oxenstierna G, Sedvall G, Wiesel FA. Alfredsson G, et al. Acta Psychiatr Scand Suppl. 1984;311:49-74. doi: 10.1111/j.1600-0447.1984.tb06859.x. Acta Psychiatr Scand Suppl. 1984. PMID: 6199949 Clinical Trial.
Schizophrenic patients were treated with fixed doses of sulpiride (800 mg) or chlorpromazine (400 mg) during eight weeks using a double-blind design. ...The results also support the view that sulpiride has a more selective effect on central dopaminergic mechanisms than …
Schizophrenic patients were treated with fixed doses of sulpiride (800 mg) or chlorpromazine (400 mg) during eight weeks using a doub …
892 results