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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 1
1959 1
1960 4
1961 1
1962 7
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1964 6
1965 2
1966 6
1967 8
1968 2
1969 3
1970 6
1971 1
1972 2
1973 2
1974 2
1975 1
1976 5
1978 4
1979 4
1980 1
1981 2
1982 2
1983 1
1984 2
1985 1
1986 3
1987 1
1988 5
1989 3
1990 5
1991 2
1992 6
1993 11
1994 15
1995 29
1996 33
1997 37
1998 50
1999 40
2000 32
2001 39
2002 32
2003 44
2004 31
2005 28
2006 42
2007 28
2008 24
2009 22
2010 21
2011 22
2012 32
2013 33
2014 29
2015 23
2016 28
2017 14
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2020 27
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2022 23
2023 14
2024 16
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954 results

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Page 1
Chlorzoxazone.
[No authors listed] [No authors listed] 2017 Jan 30. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2017 Jan 30. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643467 Free Books & Documents. Review.
Chlorzoxazone is a centrally acting muscle relaxant commonly used for low back pain. Chlorzoxazone has been linked to rare instances of acute liver injury, a few of which have been fatal....
Chlorzoxazone is a centrally acting muscle relaxant commonly used for low back pain. Chlorzoxazone has been linked to rare ins …
Interactions between herbal medicines and prescribed drugs: an updated systematic review.
Izzo AA, Ernst E. Izzo AA, et al. Drugs. 2009;69(13):1777-98. doi: 10.2165/11317010-000000000-00000. Drugs. 2009. PMID: 19719333
Kava (Piper methysticum) increases the clearance of chlorzoxazone (a CYP2E1 substrate) and may interact with alprazolam, levodopa and paroxetine. Garlic (Allium sativum) interacts with chlorpropamide, fluindione, ritonavir and warfarin; it also reduces plasma concentration …
Kava (Piper methysticum) increases the clearance of chlorzoxazone (a CYP2E1 substrate) and may interact with alprazolam, levodopa and …
CHLORZOXAZONE.
[No authors listed] [No authors listed] J Am Med Assoc. 1959 May 9;170(2):195. J Am Med Assoc. 1959. PMID: 13641004 No abstract available.
The CYTONOX trial.
Gade C, Mikus G, Christensen HR, Dalhoff KP, Holm JC, Holst H. Gade C, et al. Dan Med J. 2016 May;63(5):A5226. Dan Med J. 2016. PMID: 27127017 Free article. Clinical Trial.
The primary end points are: in vivo clearance of CYP3A4, CYP2E1 and CYP1A2 substrates, which will be defined by using well-tested probes; midazolam, chlorzoxazone and caffeine. Each of the probes will be administered as a single dose. Subsequently, blood and urine samples …
The primary end points are: in vivo clearance of CYP3A4, CYP2E1 and CYP1A2 substrates, which will be defined by using well-tested probes; mi …
Adjuvant analgesics for spine surgery.
Nielsen RV. Nielsen RV. Dan Med J. 2018 Mar;65(3):B5468. Dan Med J. 2018. PMID: 29510816 Free article. Review.
In study III we explored the effect of 500 mg of oral chlorzoxazone on acute postoperative pain and opioid consumption in patients with moderate to severe pain after spine surgery and found no effect of chlorzoxazone compared to placebo. ...Possibly ketamine also …
In study III we explored the effect of 500 mg of oral chlorzoxazone on acute postoperative pain and opioid consumption in patients wi …
Therapeutic efficacy of the BKCa channel opener chlorzoxazone in a mouse model of Fragile X syndrome.
Ferraguto C, Piquemal-Lagoueillat M, Lemaire V, Moreau MM, Trazzi S, Uguagliati B, Ciani E, Bertrand SS, Louette E, Bontempi B, Pietropaolo S. Ferraguto C, et al. Neuropsychopharmacology. 2024 Dec;49(13):2032-2041. doi: 10.1038/s41386-024-01956-6. Epub 2024 Sep 2. Neuropsychopharmacology. 2024. PMID: 39223257 Free PMC article.
Chlorzoxazone, administered either acutely or chronically, rescued hyperactivity and acoustic hyper-responsiveness as well as impaired social interactions exhibited by Fmr1-KO mice. Chlorzoxazone was more efficacious in alleviating these phenotypes than gaboxadol an …
Chlorzoxazone, administered either acutely or chronically, rescued hyperactivity and acoustic hyper-responsiveness as well as impaire …
Obesity-induced CYP2E1 activity in children.
Gade C, Dalhoff K, Petersen T, Riis T, Schmeltz C, Chabanova E, Christensen HR, Mikus G, Burhenne J, Holm JC, Holst H. Gade C, et al. Br J Clin Pharmacol. 2019 Feb;85(2):458-459. doi: 10.1111/bcp.13813. Epub 2018 Dec 9. Br J Clin Pharmacol. 2019. PMID: 30537026 Free PMC article. No abstract available.
Chlorzoxazone Alleviates Experimental Autoimmune Encephalomyelitis via Inhibiting IL-6 Secretion of Dendritic Cells.
Lv J, Han M, Xiang Z, Gong R, Shi C, Hua Q, Zhang R, Du C. Lv J, et al. J Immunol. 2022 Apr 1;208(7):1545-1553. doi: 10.4049/jimmunol.2100169. Epub 2022 Mar 11. J Immunol. 2022. PMID: 35277421
Moreover, the proportion of Th17 cells in the spleen and CNS decreased significantly. In vitro experiments showed that chlorzoxazone treatment significantly reduced DC-derived IL-6 production. In the DC-T cell coculture experiment, significantly decreased Th17 differentiat …
Moreover, the proportion of Th17 cells in the spleen and CNS decreased significantly. In vitro experiments showed that chlorzoxazone …
Update on the Pharmacotherapy of Cerebellar Ataxia and Nystagmus.
Feil K, Bremova T, Muth C, Schniepp R, Teufel J, Strupp M. Feil K, et al. Cerebellum. 2016 Feb;15(1):38-42. doi: 10.1007/s12311-015-0733-1. Cerebellum. 2016. PMID: 26519380 Review.
In both diseases the sustained-release form is evidently also efficient; (c) 4-AP in cerebellar gait ataxia: evidence comes from two observational studies. (d) chlorzoxazone in DBN which, however, was so far demonstrated in only one observational study; (e) the modified am …
In both diseases the sustained-release form is evidently also efficient; (c) 4-AP in cerebellar gait ataxia: evidence comes from two observa …
954 results