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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 2
2001 3
2002 3
2003 7
2004 11
2005 25
2006 33
2007 34
2008 28
2009 22
2010 23
2011 15
2012 15
2013 13
2014 11
2015 12
2016 16
2017 12
2018 10
2019 7
2020 28
2021 17
2022 3
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316 results
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Page 1
Local and systemic safety of intranasal corticosteroids.
Sastre J, Mosges R. Sastre J, et al. J Investig Allergol Clin Immunol. 2012;22(1):1-12. J Investig Allergol Clin Immunol. 2012. PMID: 22448448 Free article. Review.
As seen in numerous studies, INCs demonstrate markedly reduced systemic bioavailability compared with oral and even inhaled corticosteroids and have shown an excellent safety profile over 3 decades of use. Nonetheless, concerns remain among some prescribers and patients th …
As seen in numerous studies, INCs demonstrate markedly reduced systemic bioavailability compared with oral and even inhaled corticosteroids …
Ciclesonide.
Reynolds NA, Scott LJ. Reynolds NA, et al. Drugs. 2004;64(5):511-9; discussion 520-1. doi: 10.2165/00003495-200464050-00005. Drugs. 2004. PMID: 14977388 Clinical Trial.
Inhaled ciclesonide 80 or 320 microg daily improved asthma symptom scores and decreased the use of rescue medication by a similar, significant amount to budesonide 400 microg/day in two 12-week studies. Inhaled ciclesonide was generally well tolerated in pati …
Inhaled ciclesonide 80 or 320 microg daily improved asthma symptom scores and decreased the use of rescue medication by a simi …
Ciclesonide and the treatment of asthma.
Korenblat PE. Korenblat PE. Expert Opin Pharmacother. 2010 Feb;11(3):463-79. doi: 10.1517/14656560903575647. Expert Opin Pharmacother. 2010. PMID: 20102309 Review.
Moreover, studies have found that ciclesonide is as effective as other ICSs in establishing and controlling disease symptoms. Controlled clinical trials also showed that ciclesonide is associated with minimal systemic and local treatment-related adverse events. ...
Moreover, studies have found that ciclesonide is as effective as other ICSs in establishing and controlling disease symptoms. Control …
Ciclesonide versus other inhaled steroids for chronic asthma in children and adults.
Manning P, Gibson PG, Lasserson TJ. Manning P, et al. Cochrane Database Syst Rev. 2008 Apr 16;(2):CD007031. doi: 10.1002/14651858.CD007031. Cochrane Database Syst Rev. 2008. PMID: 18425977 Review.
SELECTION CRITERIA: Randomised parallel or crossover studies were eligible for the review. We included studies comparing ciclesonide with other steroids both at nominally equivalent dose or lower doses of ciclesonide. ...The role of ciclesonide in the managem …
SELECTION CRITERIA: Randomised parallel or crossover studies were eligible for the review. We included studies comparing ciclesonide
The systemic safety of inhaled corticosteroid therapy: a focus on ciclesonide.
Meltzer EO, Derendorf H. Meltzer EO, et al. Ann Allergy Asthma Immunol. 2006 Aug;97(2):149-57. doi: 10.1016/S1081-1206(10)60005-1. Ann Allergy Asthma Immunol. 2006. PMID: 16937743 Review.
OBJECTIVE: To review the potential systemic activity of ciclesonide and its active metabolite, desisobutyryl-ciclesonide, by evaluation of the effects on hypothalamic-pituitary-adrenal (HPA) axis function. ...CONCLUSIONS: Even at the higher doses used to treat more …
OBJECTIVE: To review the potential systemic activity of ciclesonide and its active metabolite, desisobutyryl-ciclesonide, by e …
Ciclesonide versus other inhaled corticosteroids for chronic asthma in children.
Kramer S, Rottier BL, Scholten RJ, Boluyt N. Kramer S, et al. Cochrane Database Syst Rev. 2013 Feb 28;(2):CD010352. doi: 10.1002/14651858.CD010352. Cochrane Database Syst Rev. 2013. PMID: 23450613 Free article. Review.
SELECTION CRITERIA: Randomised controlled parallel or cross-over studies were eligible for the review. We included studies comparing ciclesonide with other corticosteroids both at nominally equivalent doses or lower doses of ciclesonide. ...The resource use o …
SELECTION CRITERIA: Randomised controlled parallel or cross-over studies were eligible for the review. We included studies comparing cicl
Different types of intranasal steroids for chronic rhinosinusitis.
Chong LY, Head K, Hopkins C, Philpott C, Burton MJ, Schilder AG. Chong LY, et al. Cochrane Database Syst Rev. 2016 Apr 26;4:CD011993. doi: 10.1002/14651858.CD011993.pub2. Cochrane Database Syst Rev. 2016. PMID: 27115215 Free article. Review.
SELECTION CRITERIA: Randomised controlled trials (RCTs) with a follow-up period of at least three months comparing first-generation intranasal corticosteroids (e.g. beclomethasone dipropionate, triamcinolone acetonide, flunisolide, budesonide) with second-generation intranasal co …
SELECTION CRITERIA: Randomised controlled trials (RCTs) with a follow-up period of at least three months comparing first-generation intranas …
Ciclesonide Impacts Clinicopathological Features of Eosinophilic Esophagitis.
Nistel M, Nguyen N, Atkins D, Miyazawa H, Burger C, Furuta GT, Menard-Katcher C. Nistel M, et al. J Allergy Clin Immunol Pract. 2021 Nov;9(11):4069-4074. doi: 10.1016/j.jaip.2021.06.058. Epub 2021 Jul 19. J Allergy Clin Immunol Pract. 2021. PMID: 34293498
Pharmacologic treatment has largely relied on repurposing corticosteroids. Ciclesonide (CIC) is a corticosteroid for the treatment of asthma with biochemical properties that improve topical potency. ...RESULTS: A total of 281 patients were treated with CIC and 81 met crite …
Pharmacologic treatment has largely relied on repurposing corticosteroids. Ciclesonide (CIC) is a corticosteroid for the treatment of …
Ciclesonide--a novel corticosteroid for the management of asthma.
Chopra D, Bhandari B, Wardhan N. Chopra D, et al. Curr Clin Pharmacol. 2012 May;7(2):73-7. doi: 10.2174/157488412800228901. Curr Clin Pharmacol. 2012. PMID: 22283615 Review.
Ciclesonide is a prodrug metabolized by esterases to desisobutyryl ciclesonide (des-CIC), an active metabolite with a 100-fold greater affinity for the glucocorticoid receptor. It has shown to improve pulmonary functions, reduce the need for oral corticosteroids (OC
Ciclesonide is a prodrug metabolized by esterases to desisobutyryl ciclesonide (des-CIC), an active metabolite with a 100-fold
316 results