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1984 2
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1,672 results

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Page 1
Sulopenem or Ciprofloxacin for the Treatment of Uncomplicated Urinary Tract Infections in Women: A Phase 3, Randomized Trial.
Dunne MW, Aronin SI, Das AF, Akinapelli K, Zelasky MT, Puttagunta S, Boucher HW. Dunne MW, et al. Clin Infect Dis. 2023 Jan 6;76(1):66-77. doi: 10.1093/cid/ciac738. Clin Infect Dis. 2023. PMID: 36069202 Free PMC article. Clinical Trial.
In patients with ciprofloxacin-nonsusceptible baseline pathogens, sulopenem was compared for superiority over ciprofloxacin; in patients with ciprofloxacin-susceptible pathogens, the agents were compared for noninferiority. ...CONCLUSIONS: Sulopenem was nonin …
In patients with ciprofloxacin-nonsusceptible baseline pathogens, sulopenem was compared for superiority over ciprofloxacin; i …
Ciprofloxacin.
Terp DK, Rybak MJ. Terp DK, et al. Drug Intell Clin Pharm. 1987 Jul-Aug;21(7-8):568-74. doi: 10.1177/1060028087021007-801. Drug Intell Clin Pharm. 1987. PMID: 3301247 Review.
Clinical trials using the oral preparation of ciprofloxacin have demonstrated its effectiveness in a wide variety of infections. In addition, extensive clinical trials with the intravenous preparation are underway. In vitro and in vivo studies with ciprofloxacin hav …
Clinical trials using the oral preparation of ciprofloxacin have demonstrated its effectiveness in a wide variety of infections. In a …
A phase ib clinical trial of oral ciprofloxacin and etoposide in subjects with resistant acute myeloid leukemia.
Gera K, Cline C, Al-Mansour Z, Medvec A, Lee JH, Galochkina Z, Hsu J, Hiemenz J, Farhadfar N, Dean EA, Wingard JR, Brown R. Gera K, et al. Leuk Lymphoma. 2024 Oct;65(10):1502-1510. doi: 10.1080/10428194.2024.2361111. Epub 2024 Jun 6. Leuk Lymphoma. 2024. PMID: 38841781 Clinical Trial.
A phase 1b study was conducted to evaluate the safety and feasibility of ciprofloxacin and etoposide combination treatment in subjects with relapsed and refractory acute myeloid leukemia. ...Utilizing the standard '3 + 3' design, escalating ciprofloxacin doses (750 …
A phase 1b study was conducted to evaluate the safety and feasibility of ciprofloxacin and etoposide combination treatment in subject …
A randomized clinical trial of ciprofloxacin and metronidazole to treat acute pouchitis.
Shen B, Achkar JP, Lashner BA, Ormsby AH, Remzi FH, Brzezinski A, Bevins CL, Bambrick ML, Seidner DL, Fazio VW. Shen B, et al. Inflamm Bowel Dis. 2001 Nov;7(4):301-5. doi: 10.1097/00054725-200111000-00004. Inflamm Bowel Dis. 2001. PMID: 11720319 Clinical Trial.
Both ciprofloxacin and metronidazole are effective in treating acute pouchitis with significant reduction of the PDAI scores. ...Ciprofloxacin should be considered as one of the first-line therapies for acute pouchitis....
Both ciprofloxacin and metronidazole are effective in treating acute pouchitis with significant reduction of the PDAI scores. ...C …
Efficacy and Safety of Ciprofloxacin Plus Fluocinolone Acetonide Among Patients With Acute Otitis Externa: A Randomized Clinical Trial.
Chu L, Acosta AM, Aazami H, Dennis P, De Valle O, Ehmer D Jr, Hedrick JA, Ansley JF. Chu L, et al. JAMA Netw Open. 2022 Jul 1;5(7):e2221699. doi: 10.1001/jamanetworkopen.2022.21699. JAMA Netw Open. 2022. PMID: 35834251 Free PMC article. Clinical Trial.
IMPORTANCE: Ciprofloxacin, 0.3%, plus fluocinolone acetonide, 0.025%, otic solution seems to be efficacious and safe in treating acute otitis externa (AOE) compared with ciprofloxacin, 0.3%, or fluocinolone acetonide, 0.025%, otic solution alone. OBJECTIVE: To evalu …
IMPORTANCE: Ciprofloxacin, 0.3%, plus fluocinolone acetonide, 0.025%, otic solution seems to be efficacious and safe in treating acut …
Intravenous ciprofloxacin and ceftazidime in serious infections. A prospective, controlled clinical trial with third-party blinding.
Sifuentes-Osornio J, Macías A, Amieva RI, Ramos A, Ruiz-Palacios GM. Sifuentes-Osornio J, et al. Am J Med. 1989 Nov 30;87(5A):202S-205S. doi: 10.1016/0002-9343(89)90059-4. Am J Med. 1989. PMID: 2686425 Clinical Trial.
Oral ciprofloxacin has been shown to be effective in the treatment of infections due to gram-positive cocci and gram-negative rods. ...The clinical responses were cure or improvement in 31 ciprofloxacin cases/21 ceftazidime cases; failure, zero/four; and indetermina …
Oral ciprofloxacin has been shown to be effective in the treatment of infections due to gram-positive cocci and gram-negative rods. . …
Ciprofloxacin: chemistry, mechanism of action, resistance, antimicrobial spectrum, pharmacokinetics, clinical trials, and adverse reactions.
LeBel M. LeBel M. Pharmacotherapy. 1988;8(1):3-33. doi: 10.1002/j.1875-9114.1988.tb04058.x. Pharmacotherapy. 1988. PMID: 2836821 Review.
Ciprofloxacin, considered a benchmark when comparing new fluoroquinolones, shares with these agents a common mechanism of action: inhibition of DNA gyrase. While ciprofloxacin demonstrated a fairly good activity against gram-positive bacteria, it is against gram-neg …
Ciprofloxacin, considered a benchmark when comparing new fluoroquinolones, shares with these agents a common mechanism of action: inh …
Efficacy and Safety of Ciprofloxacin Plus Fluocinolone in Otitis Media With Tympanostomy Tubes in Pediatric Patients: A Randomized Clinical Trial.
Spektor Z, Pumarola F, Ismail K, Lanier B, Hussain I, Ansley J, Butehorn HF 3rd, Esterhuizen K, Byers J, Douglis F, Lansford B, Hernández FJ. Spektor Z, et al. JAMA Otolaryngol Head Neck Surg. 2017 Apr 1;143(4):341-349. doi: 10.1001/jamaoto.2016.3537. JAMA Otolaryngol Head Neck Surg. 2017. PMID: 28006041 Clinical Trial.
RESULTS: A total of 662 children participating in the 2 studies were randomized to receive ciprofloxacin plus fluocinolone (n = 223), ciprofloxacin alone (n = 221), or fluocinolone alone (n = 218). ...CONCLUSIONS AND RELEVANCE: The combination of ciprofloxacin …
RESULTS: A total of 662 children participating in the 2 studies were randomized to receive ciprofloxacin plus fluocinolone (n = 223), …
Clinical and chemical interactions between iron preparations and ciprofloxacin.
Kara M, Hasinoff BB, McKay DW, Campbell NR. Kara M, et al. Br J Clin Pharmacol. 1991 Mar;31(3):257-61. doi: 10.1111/j.1365-2125.1991.tb05526.x. Br J Clin Pharmacol. 1991. PMID: 2054264 Free PMC article. Clinical Trial.
Ciprofloxacin seems to bind to ferric ion in a ratio of 3:1 by interacting with the 4-keto and 3-carboxyl groups on ciprofloxacin. 4. The formation of a ferric ion-ciprofloxacin complex is probably the cause of the reduction in ciprofloxacin bioavailab …
Ciprofloxacin seems to bind to ferric ion in a ratio of 3:1 by interacting with the 4-keto and 3-carboxyl groups on ciprofloxacin …
Antibiotic prophylaxis for ERCP: a randomized clinical trial comparing ciprofloxacin and cefuroxime in 200 patients at high risk of cholangitis.
Mehal WZ, Culshaw KD, Tillotson GS, Chapman RW. Mehal WZ, et al. Eur J Gastroenterol Hepatol. 1995 Sep;7(9):841-5. Eur J Gastroenterol Hepatol. 1995. PMID: 8574715 Clinical Trial.
Cholangitis was diagnosed in one patient from each of the two trial groups. Blood cultures from the patient on ciprofloxacin gave negative results, but a post-ERCP blood sample from the patient on cefuroxime grew Pseudomonas aeruginosa, which was sensitive to ciprofloxa …
Cholangitis was diagnosed in one patient from each of the two trial groups. Blood cultures from the patient on ciprofloxacin gave neg …
1,672 results