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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1969 7
1970 20
1971 44
1972 70
1973 97
1974 137
1975 173
1976 190
1977 242
1978 239
1979 290
1980 400
1981 458
1982 528
1983 578
1984 636
1985 642
1986 633
1987 629
1988 629
1989 694
1990 568
1991 625
1992 542
1993 596
1994 518
1995 542
1996 433
1997 463
1998 412
1999 440
2000 401
2001 361
2002 364
2003 379
2004 344
2005 336
2006 307
2007 270
2008 269
2009 283
2010 283
2011 320
2012 308
2013 281
2014 300
2015 299
2016 333
2017 280
2018 252
2019 234
2020 242
2021 230
2022 224
2023 195
2024 209
2025 246
2026 199

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19,517 results

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Page 1
A meta-analysis of clonidine for symptoms of attention-deficit hyperactivity disorder.
Connor DF, Fletcher KE, Swanson JM. Connor DF, et al. J Am Acad Child Adolesc Psychiatry. 1999 Dec;38(12):1551-9. doi: 10.1097/00004583-199912000-00017. J Am Acad Child Adolesc Psychiatry. 1999. PMID: 10596256 Clinical Trial.
OBJECTIVE: Meta-analysis was used to review the literature on the clinical use of clonidine to treat symptoms of attention-deficit hyperactivity disorder (ADHD). METHOD: A review of the literature from 1980 to 1999 revealed 39 studies that reported clonidine's …
OBJECTIVE: Meta-analysis was used to review the literature on the clinical use of clonidine to treat symptoms of attention-deficit hy …
Clonidine toxicity revisited.
Seger DL. Seger DL. J Toxicol Clin Toxicol. 2002;40(2):145-55. doi: 10.1081/clt-120004402. J Toxicol Clin Toxicol. 2002. PMID: 12126186 Review.
The incidence of clonidine overdose is increasing, yet there is a paucity of new information regarding treatment options for clonidine toxicity. ...Neurotransmitters, receptors, endogenous opioids, and baseline sympathetic tone determine the clinical response to …
The incidence of clonidine overdose is increasing, yet there is a paucity of new information regarding treatment options for cloni …
Clonidine compromises human sperm functions.
Liu X, Cui Y, Qian R, Li Y, Hu Z, Chen H, Yuan Y, Luo T. Liu X, et al. Reprod Toxicol. 2026 Mar;140:109164. doi: 10.1016/j.reprotox.2026.109164. Epub 2026 Jan 8. Reprod Toxicol. 2026. PMID: 41519409
This study investigated clonidine's impact on human sperm function and progesterone-induced signaling pathways essential for fertilization. ...Most significantly, clonidine potently inhibited progesterone-induced calcium signaling, capacitation, and acrosome …
This study investigated clonidine's impact on human sperm function and progesterone-induced signaling pathways essential for f …
Clonidine-induced bradycardia.
Golusinski LL Jr, Blount BW. Golusinski LL Jr, et al. J Fam Pract. 1995 Oct;41(4):399-401. J Fam Pract. 1995. PMID: 7561715
Clonidine is an alpha-adrenergic agent that is used in the treatment of hypertension. Bradycardia has been described as a common effect of clonidine poisoning, but has rarely been described as a side effect at commonly prescribed dosages. Bradyarrhythmias, as a side …
Clonidine is an alpha-adrenergic agent that is used in the treatment of hypertension. Bradycardia has been described as a common effe …
Topical clonidine antinociception.
Dogrul A, Uzbay TI. Dogrul A, et al. Pain. 2004 Oct;111(3):385-391. doi: 10.1016/j.pain.2004.07.020. Pain. 2004. PMID: 15363883
Clonidine, an alpha-2 adrenergic agonist, is an extremely potent antinociceptive agent. ...The magnitude of antinociception was dependent upon the duration of exposure to the clonidine solution. Further, the antinociceptive activity of clonidine was limited t …
Clonidine, an alpha-2 adrenergic agonist, is an extremely potent antinociceptive agent. ...The magnitude of antinociception was depen …
Clonidine and alcohol withdrawal.
Cushman P Jr. Cushman P Jr. Adv Alcohol Subst Abuse. 1987;7(1):17-28. Adv Alcohol Subst Abuse. 1987. PMID: 3327372 Review.
Clonidine and locus ceruleus lesions, in animals with alcohol dependency as with the opiates, modify alcohol withdrawal. Both alcohol loading and withdrawal from steady alcohol use alter catecholamines in man and animals. Clonidine's potential to treat alcoho …
Clonidine and locus ceruleus lesions, in animals with alcohol dependency as with the opiates, modify alcohol withdrawal. Both alcohol …
Clonidine for smoking cessation.
Gourlay SG, Stead LF, Benowitz NL. Gourlay SG, et al. Cochrane Database Syst Rev. 2004;2004(3):CD000058. doi: 10.1002/14651858.CD000058.pub2. Cochrane Database Syst Rev. 2004. PMID: 15266422 Free PMC article.
OBJECTIVES: The aim of this review is to determine clonidine's effectiveness in helping smokers to quit. SEARCH STRATEGY: We searched the Cochrane Tobacco Addiction Group trials register for trials of clonidine. ...There was a statistically significant effect …
OBJECTIVES: The aim of this review is to determine clonidine's effectiveness in helping smokers to quit. SEARCH STRATEGY: We s …
Clonidine for smoking cessation.
Gourlay SG, Stead LF, Benowitz NL. Gourlay SG, et al. Cochrane Database Syst Rev. 2000;(2):CD000058. doi: 10.1002/14651858.CD000058. Cochrane Database Syst Rev. 2000. Update in: Cochrane Database Syst Rev. 2004;(3):CD000058. doi: 10.1002/14651858.CD000058.pub2. PMID: 10796479 Updated.
OBJECTIVES: The aim of this review is to determine clonidine's effectiveness in helping smokers to quit. SEARCH STRATEGY: We searched the Cochrane Tobacco Addiction Group trials register. ...There was a statistically significant effect of clonidine in one of …
OBJECTIVES: The aim of this review is to determine clonidine's effectiveness in helping smokers to quit. SEARCH STRATEGY: We s …
Pharmacokinetics of clonidine.
Lowenthal DT. Lowenthal DT. J Cardiovasc Pharmacol. 1980;2 Suppl 1:S29-37. doi: 10.1097/00005344-198000021-00004. J Cardiovasc Pharmacol. 1980. PMID: 6154834 Review. No abstract available.
Using Clonidine for neuromodulation in patients with postural orthostatic tachycardia syndrome.
Lin S, Kote A, Andersson T, Goldhaber JI, Tisdale JE, Li X, Chen PS, Liu X. Lin S, et al. Heart Rhythm. 2025 Sep;22(9):e781-e790. doi: 10.1016/j.hrthm.2025.05.003. Epub 2025 May 6. Heart Rhythm. 2025. PMID: 40339951
BACKGROUND: Microneurography studies showed that the alpha-2 agonist clonidine suppresses sympathetic nerve activity. However, clonidine's neuromodulation effects in ambulatory patients are unknown. ...METHODS: This prospective observational study included 33 …
BACKGROUND: Microneurography studies showed that the alpha-2 agonist clonidine suppresses sympathetic nerve activity. However, clo …
19,517 results
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