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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 3
1971 6
1972 10
1973 10
1974 13
1975 18
1976 14
1977 19
1978 18
1979 15
1980 34
1981 30
1982 32
1983 42
1984 30
1985 36
1986 37
1987 48
1988 62
1989 71
1990 50
1991 78
1992 68
1993 66
1994 76
1995 88
1996 70
1997 93
1998 86
1999 76
2000 83
2001 72
2002 65
2003 65
2004 68
2005 81
2006 53
2007 48
2008 46
2009 52
2010 32
2011 47
2012 40
2013 39
2014 52
2015 32
2016 38
2017 22
2018 23
2019 23
2020 22
2021 19
2022 16
2023 14
2024 15
2025 22
2026 6

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2,304 results

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Page 1
Intraoperative Clonidine in Spine Surgery: A Randomised Controlled Trial.
Birkebæk S, Juul N, Rasmussen MM, Uhrbrand PG, Nikolajsen L. Birkebæk S, et al. Acta Anaesthesiol Scand. 2025 Jul;69(6):e70048. doi: 10.1111/aas.70048. Acta Anaesthesiol Scand. 2025. PMID: 40331364 Free PMC article. Clinical Trial.
Data from 120 patients (49 females, 71 males, mean age 65 14 years) were available for analysis; 61 received clonidine and 59 received placebo. Post-operative intravenous morphine equivalents within 3 h were similar in the clonidine group 5 mg (0-15) and the place …
Data from 120 patients (49 females, 71 males, mean age 65 14 years) were available for analysis; 61 received clonidine and 59 recei …
A comparative trial of clonidine, propranolol and placebo in the treatment of moderate hypertension.
Wilkinson PR, Raftery EB. Wilkinson PR, et al. Br J Clin Pharmacol. 1977 Jun;4(3):289-94. doi: 10.1111/j.1365-2125.1977.tb00714.x. Br J Clin Pharmacol. 1977. PMID: 332218 Free PMC article. Clinical Trial.
Propranolol gave a greater reduction in pulse rate than clonidine (P less than 0.01) but clonidine also reduced the pulse rate significantly (P less than 0.05). There was no evidence of postural hypotension on either drug. Side-effects were more common with cloni …
Propranolol gave a greater reduction in pulse rate than clonidine (P less than 0.01) but clonidine also reduced the pulse rate …
Clonidine in opiate withdrawal: review and appraisal of clinical findings.
Washton AM, Resnick RB. Washton AM, et al. Pharmacotherapy. 1981 Sep-Oct;1(2):140-6. doi: 10.1002/j.1875-9114.1981.tb03561.x. Pharmacotherapy. 1981. PMID: 6765486 Clinical Trial.
Clonidine seems best suited for use as a transitional treatment between opiate dependence and induction onto the opiate antagonist naltrexone. Dosage regimens of clonidine must be individualized according to symptoms and side effects and closely supervised because o …
Clonidine seems best suited for use as a transitional treatment between opiate dependence and induction onto the opiate antagonist na …
Clonidine and guanfacine in hypertension.
Jain AK, Hiremath A, Michael R, Ryan JR, McMahon FG. Jain AK, et al. Clin Pharmacol Ther. 1985 Mar;37(3):271-6. doi: 10.1038/clpt.1985.39. Clin Pharmacol Ther. 1985. PMID: 3882307 Clinical Trial.
Forty percent of the subjects receiving guanfacine and 64% of subjects receiving clonidine had diastolic blood pressure elevations greater than or equal to 10 mm Hg from baseline. ...Side effects after guanfacine were much the same as those after clonidine. Guanfaci …
Forty percent of the subjects receiving guanfacine and 64% of subjects receiving clonidine had diastolic blood pressure elevations gr …
Psychiatric indications for clonidine: the neuropharmacologic and clinical basis.
Bond WS. Bond WS. J Clin Psychopharmacol. 1986 Apr;6(2):81-7. J Clin Psychopharmacol. 1986. PMID: 3517082 Clinical Trial.
Studies also indicate clonidine's value in alcohol and tobacco withdrawal syndromes. Of special interest is evidence which suggests that clonidine can reduce the duration and cost of the withdrawal process. Also discussed is clonidine's utility …
Studies also indicate clonidine's value in alcohol and tobacco withdrawal syndromes. Of special interest is evidence which sug …
Transdermal clonidine versus chlordiazepoxide in alcohol withdrawal: a randomized, controlled clinical trial.
Baumgartner GR, Rowen RC. Baumgartner GR, et al. South Med J. 1991 Mar;84(3):312-21. doi: 10.1097/00007611-199103000-00006. South Med J. 1991. PMID: 2000517 Clinical Trial.
Also, clonidine more effectively lowered elevated systolic and diastolic blood pressure and heart rate. ...We conclude that transdermal clonidine is effective treatment for the acute alcohol withdrawal syndrome....
Also, clonidine more effectively lowered elevated systolic and diastolic blood pressure and heart rate. ...We conclude that transderm …
[Clinical trial of a combination preparation of clonidine and cyclothiazide (author's transl)].
Wimmer PP. Wimmer PP. MMW Munch Med Wochenschr. 1977 Aug 26;119(34):1085-8. MMW Munch Med Wochenschr. 1977. PMID: 408656 Clinical Trial. German.
Three dosage combinations of clonidine and cyclothiazide were tested in at least 20 patients each, under clinical (4 weeks) and oupatients (longterm) conditions, in order to find a suitable combination with fewer side effects than the single drugs with at least equal effic …
Three dosage combinations of clonidine and cyclothiazide were tested in at least 20 patients each, under clinical (4 weeks) and oupat …
Clinical trial of clonidine hydrochloride as an antisecretory agent in cholera.
Rabbani GH, Butler T, Patte D, Abud RL. Rabbani GH, et al. Gastroenterology. 1989 Aug;97(2):321-5. doi: 10.1016/0016-5085(89)90067-x. Gastroenterology. 1989. PMID: 2663610 Clinical Trial.
Clonidine hydrochloride (an alpha 2-adrenoceptor agonist) was tested for antisecretory effects in patients with cholera in a randomized controlled trial. ...We conclude that clonidine causes modest reduction of stool electrolyte loss but does not significantly reduc …
Clonidine hydrochloride (an alpha 2-adrenoceptor agonist) was tested for antisecretory effects in patients with cholera in a randomiz …
A phase II clinical trial to assess the safety of clonidine in acute organophosphorus pesticide poisoning.
Perera PM, Jayamanna SF, Hettiarachchi R, Abeysinghe C, Karunatilake H, Dawson AH, Buckley NA. Perera PM, et al. Trials. 2009 Aug 20;10:73. doi: 10.1186/1745-6215-10-73. Trials. 2009. PMID: 19691854 Free PMC article. Clinical Trial.
Forty eight patients with acute organophosphate poisoning were randomized to receive either clonidine or placebo: Four to receive placebo and twelve to receive clonidine at each dose level. ...Further studies are needed to study the efficacy of clonidine as a …
Forty eight patients with acute organophosphate poisoning were randomized to receive either clonidine or placebo: Four to receive pla …
Clonidine and migraine.
Wood J, Lance J. Wood J, et al. Med J Aust. 1984 Mar 17;140(6):384. doi: 10.5694/j.1326-5377.1984.tb104128.x. Med J Aust. 1984. PMID: 6366492 Clinical Trial. No abstract available.
2,304 results