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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1948 2
1949 2
1950 1
1951 1
1952 3
1953 1
1955 2
1956 2
1957 1
1959 3
1960 3
1961 1
1962 2
1970 2
1971 4
1972 16
1973 15
1974 51
1975 35
1976 48
1977 39
1978 46
1979 51
1980 37
1981 41
1982 40
1983 40
1984 54
1985 55
1986 51
1987 43
1988 43
1989 54
1990 47
1991 48
1992 61
1993 41
1994 57
1995 72
1996 65
1997 58
1998 77
1999 75
2000 85
2001 71
2002 99
2003 79
2004 87
2005 83
2006 79
2007 70
2008 90
2009 65
2010 83
2011 92
2012 95
2013 100
2014 94
2015 109
2016 100
2017 92
2018 98
2019 92
2020 110
2021 110
2022 94
2023 91
2024 23

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3,340 results

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Page 1
Clotrimazole as a pharmaceutical: past, present and future.
Crowley PD, Gallagher HC. Crowley PD, et al. J Appl Microbiol. 2014 Sep;117(3):611-7. doi: 10.1111/jam.12554. Epub 2014 Jun 30. J Appl Microbiol. 2014. PMID: 24863842 Free article. Review.
Clotrimazole is a broad-spectrum antimycotic drug mainly used for the treatment of Candida albicans and other fungal infections. ...Clotrimazole is a very well-tolerated product with few side effects, although there is some drug resistance appearing among immunocomp
Clotrimazole is a broad-spectrum antimycotic drug mainly used for the treatment of Candida albicans and other fungal infections. ...
Clotrimazole-related allergic contact dermatitis.
Napolitano M, Cappello M, Festa B, Patruno C. Napolitano M, et al. G Ital Dermatol Venereol. 2020 Jun;155(3):355-357. doi: 10.23736/S0392-0488.18.05943-6. Epub 2018 Oct 22. G Ital Dermatol Venereol. 2020. PMID: 30350555 No abstract available.
Clotrimazole-Based Modulators of the TRPM3 Ion Channel Reveal Narrow Structure-Activity Relationship.
Kahler JP, Aloi VD, Miedes Aliaga J, Kerselaers S, Voets T, Vriens J, Verhelst SHL, Barniol-Xicota M. Kahler JP, et al. ACS Chem Biol. 2023 Mar 17;18(3):456-464. doi: 10.1021/acschembio.2c00672. Epub 2023 Feb 10. ACS Chem Biol. 2023. PMID: 36762958
In the presence of the endogenous TRPM3 ligand, pregnenolone sulfate (PS), the antifungal compound clotrimazole (Clt) augments Ca(2+) signaling and opens a non-canonical pore, permeable to Na(+), which aggravates TRPM3-induced pain. ...
In the presence of the endogenous TRPM3 ligand, pregnenolone sulfate (PS), the antifungal compound clotrimazole (Clt) augments Ca(2+) …
Clotrimazole: a review of its antifungal activity and therapeutic efficacy.
Sawyer PR, Brogden RN, Pinder RM, Speight TM, Avery. Sawyer PR, et al. Drugs. 1975;9(6):424-47. doi: 10.2165/00003495-197509060-00003. Drugs. 1975. PMID: 1097234 Review.
Clotrimazole 2, a synthetic imidazole derivative, is primarily used locally in the treatment of vaginal and skin infections due to yeasts and dermatophytes. ...A limiting factor in oral clotrimazole therapy is the high incidence of gastro-intestinal disturbances and
Clotrimazole 2, a synthetic imidazole derivative, is primarily used locally in the treatment of vaginal and skin infections due to ye
Clotrimazole Fluidizes Phospholipid Membranes and Localizes at the Hydrophobic Part near the Polar Part of the Membrane.
Ausili A, Yakymenko I, Teruel JA, Gómez-Fernández JC. Ausili A, et al. Biomolecules. 2021 Sep 2;11(9):1304. doi: 10.3390/biom11091304. Biomolecules. 2021. PMID: 34572517 Free PMC article.
In the presence of clotrimazole, all the resonances originating from POPC were shifted upfield, but mainly those corresponding to C2 and C3 of the fatty acyl, chains suggesting that clotrimazole aromatic rings preferentially locate near these carbons. ...Molecular d …
In the presence of clotrimazole, all the resonances originating from POPC were shifted upfield, but mainly those corresponding to C2 …
Clotrimazole Inhibits HCC Migration and Invasion by Modulating the ERK-p65 Signaling Pathway.
Liu X, Gao J, Sun Y, Zhang F, Guo W, Zhang S. Liu X, et al. Drug Des Devel Ther. 2022 Mar 29;16:863-871. doi: 10.2147/DDDT.S354205. eCollection 2022. Drug Des Devel Ther. 2022. PMID: 35378926 Free PMC article.
PURPOSE: Hepatocellular carcinoma (HCC), has a very high mortality rate and is the most common type of liver cancer. Clotrimazole, a traditional antifungal drug, has garnered considerable attention as a therapeutic strategy for HCC. ...CONCLUSION: These findings suggest th …
PURPOSE: Hepatocellular carcinoma (HCC), has a very high mortality rate and is the most common type of liver cancer. Clotrimazole, a …
Evaluation of clotrimazole prophylaxis on tacrolimus trough concentrations in kidney transplant recipients.
Wings E, Spinner M, Eckardt J. Wings E, et al. Transpl Infect Dis. 2022 Aug;24(4):e13882. doi: 10.1111/tid.13882. Epub 2022 Jun 17. Transpl Infect Dis. 2022. PMID: 35689488 Free PMC article.
BACKGROUND: Clotrimazole troches are used as prophylaxis against oropharyngeal candidiasis post-transplant and have limited systemic absorption. ...No statistically significant differences in the rate of for-cause allograft biopsies (4.9% vs. 9.7%, p = 0.264) or incidence …
BACKGROUND: Clotrimazole troches are used as prophylaxis against oropharyngeal candidiasis post-transplant and have limited systemic …
Comparison of the Inhibitory Effects of Clotrimazole and Ketoconazole against Human Carboxylesterase 2.
Zhao T, Wang D, Zhao S, Chen J, Dou T, Ge G, Wang C, Meng Q, Sun H, Liu K, Wu J. Zhao T, et al. Curr Drug Metab. 2021;22(5):391-398. doi: 10.2174/1389200222666210210115509. Curr Drug Metab. 2021. PMID: 33568030
However, the interactions between hCE2, clotrimazole, and ketoconazole remain unclear. OBJECTIVE: The objective of this study was to investigate and compare the inhibition behaviors of the two antifungal agents, ketoconazole and clotrimazole, on the human liver micr …
However, the interactions between hCE2, clotrimazole, and ketoconazole remain unclear. OBJECTIVE: The objective of this study was to …
IK Channel-Independent Effects of Clotrimazole and Senicapoc on Cancer Cells Viability and Migration.
Zuccolini P, Barbieri R, Sbrana F, Picco C, Gavazzo P, Pusch M. Zuccolini P, et al. Int J Mol Sci. 2023 Nov 14;24(22):16285. doi: 10.3390/ijms242216285. Int J Mol Sci. 2023. PMID: 38003471 Free PMC article.
Clotrimazole and senicapoc induced a decrease in viability and the migration of both WM266-4 and Panc-1 cells irrespective of IK expression levels. ...Neither clotrimazole nor senicapoc altered the intracellular Ca(2+) concentration. ...
Clotrimazole and senicapoc induced a decrease in viability and the migration of both WM266-4 and Panc-1 cells irrespective of IK expr
1-trityl-4-nitroimidazole.
Skrzypczak-Jankun E, Kurumbail RG. Skrzypczak-Jankun E, et al. Acta Crystallogr C. 1996 Jan 15;52 ( Pt 1):189-91. doi: 10.1107/s0108270195010183. Acta Crystallogr C. 1996. PMID: 8808102
3,340 results