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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 2
1973 1
1978 2
1982 1
1987 1
1988 1
1989 5
1990 1
1991 2
1992 1
1993 1
1994 2
1995 1
1997 1
2002 2
2003 2
2004 1
2005 1
2006 1
2008 1
2009 5
2010 2
2011 5
2012 1
2013 2
2014 1
2015 2
2016 2
2017 1
2020 2
2021 2
2023 0
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54 results
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Page 1
Randomized clinical trial of bedtime sublingual cyclobenzaprine (TNX-102 SL) in military-related PTSD and the role of sleep quality in treatment response.
Sullivan GM, Gendreau RM, Gendreau J, Peters P, Peters A, Engels J, Daugherty BL, Vaughn B, Weathers FW, Lederman S. Sullivan GM, et al. Psychiatry Res. 2021 Jul;301:113974. doi: 10.1016/j.psychres.2021.113974. Epub 2021 Apr 30. Psychiatry Res. 2021. PMID: 33979763 Free article. Clinical Trial.
This 12-week randomized multicenter trial evaluated efficacy and safety of TNX-102 SL, a bedtime sublingual formulation of cyclobenzaprine, in patients with military-related PTSD randomized to TNX-102 SL 2.8 mg or 5.6 mg, or placebo. ...
This 12-week randomized multicenter trial evaluated efficacy and safety of TNX-102 SL, a bedtime sublingual formulation of cyclobenzaprin
Comparison of amitriptyline, cyclobenzaprine, and placebo in the treatment of fibromyalgia. A randomized, double-blind clinical trial.
Carette S, Bell MJ, Reynolds WJ, Haraoui B, McCain GA, Bykerk VP, Edworthy SM, Baron M, Koehler BE, Fam AG, et al. Carette S, et al. Arthritis Rheum. 1994 Jan;37(1):32-40. doi: 10.1002/art.1780370106. Arthritis Rheum. 1994. PMID: 8129762 Clinical Trial.
OBJECTIVE: To compare the relative efficacy and tolerability of amitriptyline, cyclobenzaprine, and placebo in the treatment of fibromyalgia, and to identify predictors of response to amitriptyline and cyclobenzaprine. METHODS: Two hundred eight patients who fulfill …
OBJECTIVE: To compare the relative efficacy and tolerability of amitriptyline, cyclobenzaprine, and placebo in the treatment of fibro …
Patient education and self-care for the management of jaw pain upon awakening: a randomized controlled clinical trial comparing the effectiveness of adding pharmacologic treatment with cyclobenzaprine or tizanidine.
Alencar FG Jr, Viana PG, Zamperini C, Becker A. Alencar FG Jr, et al. J Oral Facial Pain Headache. 2014 Spring;28(2):119-27. doi: 10.11607/ofph.963. J Oral Facial Pain Headache. 2014. PMID: 24822235 Clinical Trial.
AIMS: To compare the effectiveness of adding cyclobenzaprine, tizanidine, or placebo to patient education and a self-care management program for patients with myofascial pain and specifically presenting with jaw pain upon awakening. ...However, no significant differences a …
AIMS: To compare the effectiveness of adding cyclobenzaprine, tizanidine, or placebo to patient education and a self-care management …
The effectiveness of adding pharmacologic treatment with clonazepam or cyclobenzaprine to patient education and self-care for the treatment of jaw pain upon awakening: a randomized clinical trial.
Herman CR, Schiffman EL, Look JO, Rindal DB. Herman CR, et al. J Orofac Pain. 2002 Winter;16(1):64-70. J Orofac Pain. 2002. PMID: 11889661 Clinical Trial.
Subjects were randomized into 1 of 3 groups: clonazepam (0.5 mg/night), cyclobenzaprine (10 mg/night), or placebo. The primary outcome measure was the subjects' average intensity of jaw pain upon awakening over the prior week. ...Between-group differences demonstrated a st …
Subjects were randomized into 1 of 3 groups: clonazepam (0.5 mg/night), cyclobenzaprine (10 mg/night), or placebo. The primary outcom …
Comparison of the single-dose pharmacokinetics of once-daily cyclobenzaprine extended-release 30 mg and cyclobenzaprine immediate-release 10 mg three times daily in the elderly: a randomized, open-label, crossover study.
Darwish M, Xie F. Darwish M, et al. Drugs Aging. 2009;26(2):95-101. doi: 10.2165/0002512-200926020-00001. Drugs Aging. 2009. PMID: 19220066 Clinical Trial.
Volunteers were assigned to either CER or CIR on days 1 and 15 (separated by a 14-day washout). Outcome measures included area under the plasma cyclobenzaprine concentration versus time curve (AUC) to 168 hours (AUC168) and infinity (AUC infinity), peak plasma cyclobenz
Volunteers were assigned to either CER or CIR on days 1 and 15 (separated by a 14-day washout). Outcome measures included area under the pla …
Clinical trials in fibrositis: a critical review and future directions.
Gabriel SE, Bombardier C. Gabriel SE, et al. J Rheumatol Suppl. 1989 Nov;19:177-9. J Rheumatol Suppl. 1989. PMID: 2691677 Review.
Therapeutic interventions included physical fitness, biofeedback, acupuncture, dothiepin, imipramine, cyclobenzaprine, S-adenosylmethionine and amitriptyline. The design and analysis of the randomized, controlled studies render their results reliable. ...
Therapeutic interventions included physical fitness, biofeedback, acupuncture, dothiepin, imipramine, cyclobenzaprine, S-adenosylmeth …
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
Friedman BW, Dym AA, Davitt M, Holden L, Solorzano C, Esses D, Bijur PE, Gallagher EJ. Friedman BW, et al. JAMA. 2015 Oct 20;314(15):1572-80. doi: 10.1001/jama.2015.13043. JAMA. 2015. PMID: 26501533 Clinical Trial.
At 1-week follow-up, the mean RMDQ improvement was 9.8 in the placebo group, 10.1 in the cyclobenzaprine group, and 11.1 in the oxycodone/acetaminophen group. Between-group difference in mean RMDQ improvement for cyclobenzaprine vs placebo was 0.3 (98.3% CI, -2.6 to …
At 1-week follow-up, the mean RMDQ improvement was 9.8 in the placebo group, 10.1 in the cyclobenzaprine group, and 11.1 in the oxyco …
Pharmacokinetics and bioequivalence evaluation of cyclobenzaprine tablets.
Brioschi TM, Schramm SG, Kano EK, Koono EE, Ching TH, Serra CH, Porta V. Brioschi TM, et al. Biomed Res Int. 2013;2013:281392. doi: 10.1155/2013/281392. Epub 2013 Sep 16. Biomed Res Int. 2013. PMID: 24151591 Free PMC article. Clinical Trial.
The purpose of this study was to investigate cyclobenzaprine pharmacokinetics and to evaluate bioequivalence between two different tablet formulations containing the drug. ...Cyclobenzaprine plasma profiles for the reference and test products were similar, as well a …
The purpose of this study was to investigate cyclobenzaprine pharmacokinetics and to evaluate bioequivalence between two different ta …
An assessment of the centrally acting muscle relaxant tolperisone on driving ability and cognitive effects compared to placebo and cyclobenzaprine.
Caron J, Kaye R, Wessel T, Halseth A, Kay G. Caron J, et al. J Clin Pharm Ther. 2020 Aug;45(4):774-782. doi: 10.1111/jcpt.13165. Epub 2020 May 10. J Clin Pharm Ther. 2020. PMID: 32390248 Free PMC article. Clinical Trial.
The objective of this three-way, randomized, blinded, three-period crossover study was to assess the safety and cognitive effects of tolperisone compared to placebo and the widely used muscle relaxant cyclobenzaprine in healthy volunteers. METHODS: Subjects were randomized …
The objective of this three-way, randomized, blinded, three-period crossover study was to assess the safety and cognitive effects of tolperi …
Cyclobenzaprine and naproxen versus naproxen alone in the treatment of acute low back pain and muscle spasm.
Borenstein DG, Lacks S, Wiesel SW. Borenstein DG, et al. Clin Ther. 1990 Mar-Apr;12(2):125-31. Clin Ther. 1990. PMID: 2141299 Clinical Trial.
Cyclobenzaprine was added to the naproxen regimen as an adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful, musculoskeletal conditions. ...Combination therapy was associated with more side effects, due primarily to drowsiness fro
Cyclobenzaprine was added to the naproxen regimen as an adjunct to rest and physical therapy for relief of muscle spasm associated wi
54 results