Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 2
1988 1
1989 2
1992 1
1993 1
1995 1
1997 1
1998 4
1999 2
2000 3
2001 2
2002 2
2003 3
2005 3
2006 6
2007 2
2009 9
2010 6
2011 5
2012 8
2013 9
2014 10
2015 9
2016 6
2017 7
2018 2
2026 1

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

93 results

Results by year

Filters applied: . Clear all
Page 1
Sympatho-adrenal activity and the clinical sedative effect of detomidine in horses.
Raekallio M, Leino A, Vainio O, Scheinin M. Raekallio M, et al. Equine Vet J Suppl. 1992 Feb;(11):66-8. doi: 10.1111/j.2042-3306.1992.tb04777.x. Equine Vet J Suppl. 1992. PMID: 9109965 Clinical Trial.
Venous blood samples were collected for catecholamine and cortisol determination immediately before the detomidine or saline injection and 20 mins after it. The behaviour of the horse at the time of detomidine injection and the extent of sedation were evaluated. ... …
Venous blood samples were collected for catecholamine and cortisol determination immediately before the detomidine or saline injectio …
Sedative and analgesic effects of detomidine and romifidine in horses.
Hamm D, Turchi P, Jöchle W. Hamm D, et al. Vet Rec. 1995 Apr 1;136(13):324-7. doi: 10.1136/vr.136.13.324. Vet Rec. 1995. PMID: 7604508 Clinical Trial.
Detomidine at the 10 micrograms/kg dose was similar in its effects to the two highest doses of romifidine. ...Instability and ataxia were more pronounced with detomidine than with romifidine but the effects were only slight to moderate and not regarded as a hindranc …
Detomidine at the 10 micrograms/kg dose was similar in its effects to the two highest doses of romifidine. ...Instability and ataxia …
Detomidine-butorphanol sedation in equine clinical practice.
Taylor PM, Browning AP, Harris CP. Taylor PM, et al. Vet Rec. 1988 Oct 8;123(15):388-90. doi: 10.1136/vr.123.15.388. Vet Rec. 1988. PMID: 3057722 Clinical Trial.
Combinations of detomidine (mean dose rate 13 micrograms/kg) and butorphanol (mean dose rate 26 micrograms/kg) were used to sedate 61 horses for a variety of surgical or diagnostic procedures in general equine practice. ...
Combinations of detomidine (mean dose rate 13 micrograms/kg) and butorphanol (mean dose rate 26 micrograms/kg) were used to sedate 61 …
Some effects of multiple administration of detomidine during the last trimester of equine pregnancy.
Luukkanen L, Katila T, Koskinen E. Luukkanen L, et al. Equine Vet J. 1997 Sep;29(5):400-2. doi: 10.1111/j.2042-3306.1997.tb03147.x. Equine Vet J. 1997. PMID: 9306069 Clinical Trial.
Detomidine was given to 11 pregnant mares at 3 week intervals during the last trimester of pregnancy. ...The mares exhibited conductive disturbances 2 min after detomidine administration, but fetal heart rhythm remained regular. Fetal activity was decreased at 5 min …
Detomidine was given to 11 pregnant mares at 3 week intervals during the last trimester of pregnancy. ...The mares exhibited conducti …
Field trial evaluation of detomidine as a sedative and analgesic in horses with colic.
Jöchle W. Jöchle W. Equine Vet J Suppl. 1989 Jun;(7):117-20. doi: 10.1111/j.2042-3306.1989.tb05669.x. Equine Vet J Suppl. 1989. PMID: 9118092 Clinical Trial.
In this uncontrolled clinical study 12 investigators cooperated to evaluate the analgesic and sedative effect of detomidine (DORMOSEDAN; Farmos Group Ltd; Finland) in 234 horses with abdominal pain caused by colic. ...Animals not responding to either dose of detomidine …
In this uncontrolled clinical study 12 investigators cooperated to evaluate the analgesic and sedative effect of detomidine (DORMOSED …
Sedative and antinociceptive effects of different combinations of detomidine and methadone in standing horses.
Gozalo-Marcilla M, Luna SP, Crosignani N, Filho JNP, Possebon FS, Pelligand L, Taylor PM. Gozalo-Marcilla M, et al. Vet Anaesth Analg. 2017 Sep;44(5):1116-1127. doi: 10.1016/j.vaa.2017.03.009. Epub 2017 Apr 17. Vet Anaesth Analg. 2017. PMID: 29050998 Clinical Trial.
METHODS: A total of six treatments were administered IV: saline (SAL); detomidine (5 mug kg(-1); DET); methadone (0.2 mg kg(-1); MET) alone or combined with detomidine [2.5 (MLD), 5 (MMD) or 10 (MHD) mug kg(-1)]. ...CONCLUSIONS: Methadone (0.2 mg kg(-1)) potentiated …
METHODS: A total of six treatments were administered IV: saline (SAL); detomidine (5 mug kg(-1); DET); methadone (0.2 mg kg(-1); MET) …
Detomidine: a new sedative for horses.
Clarke KW, Taylor PM. Clarke KW, et al. Equine Vet J. 1986 Sep;18(5):366-70. doi: 10.1111/j.2042-3306.1986.tb03655.x. Equine Vet J. 1986. PMID: 3533530 Clinical Trial.
Detomidine, given intravenously at doses of 5 to 30 (mean 13) micrograms/kg bodyweight (bwt), provided adequate sedation for a variety of clinical procedures in 93 per cent of administrations, and improved the ease of handling in the remaining animals. ...In experimental t …
Detomidine, given intravenously at doses of 5 to 30 (mean 13) micrograms/kg bodyweight (bwt), provided adequate sedation for a variet …
Bioavailability of detomidine administered sublingually to horses as an oromucosal gel.
Kaukinen H, Aspegrén J, Hyyppä S, Tamm L, Salonen JS. Kaukinen H, et al. J Vet Pharmacol Ther. 2011 Feb;34(1):76-81. doi: 10.1111/j.1365-2885.2010.01193.x. J Vet Pharmacol Ther. 2011. PMID: 21219348 Clinical Trial.
The objective of the study was to determine the absorption, bioavailability and sedative effect of detomidine administered to horses as an oromucosal gel compared to intravenous and intramuscular administration of detomidine injectable solution. ...The sedative effe …
The objective of the study was to determine the absorption, bioavailability and sedative effect of detomidine administered to horses …
Effect of detomidine on visceral and somatic nociception and duodenal motility in conscious adult horses.
Elfenbein JR, Sanchez LC, Robertson SA, Cole CA, Sams R. Elfenbein JR, et al. Vet Anaesth Analg. 2009 Mar;36(2):162-72. doi: 10.1111/j.1467-2995.2008.00441.x. Vet Anaesth Analg. 2009. PMID: 19239655 Clinical Trial.
OBJECTIVE: To evaluate the effects of detomidine on visceral and somatic nociception, heart and respiratory rates, sedation, and duodenal motility and to correlate these effects with serum detomidine concentrations. ...A marked, immediate decrease in amplitude of du …
OBJECTIVE: To evaluate the effects of detomidine on visceral and somatic nociception, heart and respiratory rates, sedation, and duod …
Sedation and mechanical hypoalgesia after sublingual administration of detomidine hydrochloride gel to donkeys.
Lizarraga I, Castillo-Alcala F, Varner KM, Robinson LS. Lizarraga I, et al. J Am Vet Med Assoc. 2016 Jul 1;249(1):83-9. doi: 10.2460/javma.249.1.83. J Am Vet Med Assoc. 2016. PMID: 27308886 Free article. Clinical Trial.
OBJECTIVE To compare sedative and mechanical hypoalgesic effects of sublingual administration of 2 doses of detomidine gel to donkeys. DESIGN Randomized blinded controlled trial. ANIMALS 6 healthy castrated male donkeys. PROCEDURES In a crossover study design, donkeys rece …
OBJECTIVE To compare sedative and mechanical hypoalgesic effects of sublingual administration of 2 doses of detomidine gel to donkeys …
93 results