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Page 1
Commonly prescribed medications and potential false-positive urine drug screens.
Brahm NC, Yeager LL, Fox MD, Farmer KC, Palmer TA. Brahm NC, et al. Am J Health Syst Pharm. 2010 Aug 15;67(16):1344-50. doi: 10.2146/ajhp090477. Am J Health Syst Pharm. 2010. PMID: 20689123 Review.
Reports of false-positive results were found for the following formulary and nonprescription medications: brompheniramine, bupropion, chlorpromazine, clomipramine, dextromethorphan, diphenhydramine, doxylamine, ibuprofen, naproxen, promethazine, quetiapine, quinolon …
Reports of false-positive results were found for the following formulary and nonprescription medications: brompheniramine, bupropion, chlorp …
Simultaneous determination of dextromethorphan, dextrorphan and doxylamine in human plasma by HPLC coupled to electrospray ionization tandem mass spectrometry: application to a pharmacokinetic study.
Donato JL, Koizumi F, Pereira AS, Mendes GD, De Nucci G. Donato JL, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Jun 15;899:46-56. doi: 10.1016/j.jchromb.2012.05.001. Epub 2012 May 6. J Chromatogr B Analyt Technol Biomed Life Sci. 2012. PMID: 22651995
In the present study, a fast, sensitive and robust method to quantify dextromethorphan, dextrorphan and doxylamine in human plasma using deuterated internal standards (IS) is described. ...The analytical procedure herein described was used to assess the pharmacokine …
In the present study, a fast, sensitive and robust method to quantify dextromethorphan, dextrorphan and doxylamine in human pl …
Efficacy of a single evening dose of syrup containing paracetamol, dextromethorphan hydrobromide, doxylamine succinate and ephedrine sulfate in subjects with multiple common cold symptoms.
Mizoguchi H, Wilson A, Jerdack GR, Hull JD, Goodale M, Grender JM, Tyler BA. Mizoguchi H, et al. Int J Clin Pharmacol Ther. 2007 Apr;45(4):230-6. doi: 10.5414/cpp45230. Int J Clin Pharmacol Ther. 2007. PMID: 17474541 Clinical Trial.
OBJECTIVE: The aim of this study was to evaluate the efficacy of a single night-time dose of a syrup containing paracetamol, dextromethorphan hydrobromide, doxylamine succinate and ephedrine sulfate in subjects with multiple cold symptoms. MATERIALS: A syrup contain …
OBJECTIVE: The aim of this study was to evaluate the efficacy of a single night-time dose of a syrup containing paracetamol, dextromethor …
Multidrug toxicity involving sumatriptan.
Knittel JL, Vorce SP, Levine B, Hughes RL, Bosy TZ. Knittel JL, et al. J Anal Toxicol. 2015 Jan-Feb;39(1):75-9. doi: 10.1093/jat/bku120. Epub 2014 Oct 16. J Anal Toxicol. 2015. PMID: 25324526
Carisoprodol, meprobamate, fluoxetine, doxylamine, orphenadrine, dextromethorphan and hydroxyzine were also present in the blood at the following concentrations: 3.35, 2.36, 0.63, 0.19, 0.06, 0.55 and 0.16 mg/L. ...
Carisoprodol, meprobamate, fluoxetine, doxylamine, orphenadrine, dextromethorphan and hydroxyzine were also present in the blo …
Antitussive drugs. II. Bronchopulmonary effects of dextromethorphan and doxylamine.
Aviado DM, Bianchi A, Drimal J. Aviado DM, et al. Arch Int Pharmacodyn Ther. 1975 Aug;216(2):216-24. Arch Int Pharmacodyn Ther. 1975. PMID: 1180615
Unlike codeine, dextromethorphan does not cause pulmonary vasoconstiction in the anesthetized dog. The other effects of dextromethorphan are as follwos: a rise in pulmonary resistance indicating bronchoconstriction, and increase in pulmonary blood flow relating to a …
Unlike codeine, dextromethorphan does not cause pulmonary vasoconstiction in the anesthetized dog. The other effects of dextrometh …
Safety Profile of Cough and Cold Medication Use in Pediatrics.
Green JL, Wang GS, Reynolds KM, Banner W, Bond GR, Kauffman RE, Palmer RB, Paul IM, Dart RC. Green JL, et al. Pediatrics. 2017 Jun;139(6):e20163070. doi: 10.1542/peds.2016-3070. Epub 2017 May 4. Pediatrics. 2017. PMID: 28562262
METHODS: Cases with adverse events (AEs) after ingestion of at least 1 index CCM ingredient (brompheniramine, chlorpheniramine, dextromethorphan, diphenhydramine, doxylamine, guaifenesin, phenylephrine, and pseudoephedrine) in children <12 years of age were colle …
METHODS: Cases with adverse events (AEs) after ingestion of at least 1 index CCM ingredient (brompheniramine, chlorpheniramine, dextromet …
Assessment of Pharmacologic Ingredients in Common Over-the-Counter Sinonasal Medications.
McCoul ED. McCoul ED. JAMA Otolaryngol Head Neck Surg. 2020 Sep 1;146(9):810-815. doi: 10.1001/jamaoto.2020.1836. JAMA Otolaryngol Head Neck Surg. 2020. PMID: 32672802 Free PMC article.
Only 8 unique nonanalgesic ingredients were identified among these products, with many products sold under the same brand name and with the same active ingredient. Phenylephrine hydrochloride, dextromethorphan hydrobromide, pseudoephedrine hydrochloride, guaifenesin, chlor …
Only 8 unique nonanalgesic ingredients were identified among these products, with many products sold under the same brand name and with the …
Development and validation of a generic RP-HPLC PDA method for the simultaneous separation and quantification of active ingredients in cold and cough medicines.
Dongala T, Katari NK, Palakurthi AK, Jonnalagadda SB. Dongala T, et al. Biomed Chromatogr. 2019 Nov;33(11):e4641. doi: 10.1002/bmc.4641. Epub 2019 Aug 8. Biomed Chromatogr. 2019. PMID: 31265736
A novel generic reverse phase high performance liquid chromatography (RP-HPLC) method is developed and validated for simultaneous determination of seven pharmaceutically active ingredients, namely, acetaminophen, dextromethorphan, doxylamine, phenylephrine, guaifene …
A novel generic reverse phase high performance liquid chromatography (RP-HPLC) method is developed and validated for simultaneous determinat …
30 results