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Simultaneous determination of dextromethorphan, dextrorphan, and guaifenesin in human plasma using semi-automated liquid/liquid extraction and gradient liquid chromatography tandem mass spectrometry.
Eichhold TH, McCauley-Myers DL, Khambe DA, Thompson GA, Hoke SH 2nd. Eichhold TH, et al. J Pharm Biomed Anal. 2007 Jan 17;43(2):586-600. doi: 10.1016/j.jpba.2006.07.018. Epub 2006 Aug 22. J Pharm Biomed Anal. 2007. PMID: 16930908 Clinical Trial.
A method for the simultaneous determination of dextromethorphan (DEX), dextrorphan (DET), and guaifenesin (GG) in human plasma was developed, validated, and applied to determine plasma concentrations of these compounds in samples from six clinical pharmacokinetic (P …
A method for the simultaneous determination of dextromethorphan (DEX), dextrorphan (DET), and guaifenesin (GG) in human plasma …
Clinical trial examining effectiveness of three cough syrups.
Croughan-Minihane MS, Petitti DB, Rodnick JE, Eliaser G. Croughan-Minihane MS, et al. J Am Board Fam Pract. 1993 Mar-Apr;6(2):109-15. J Am Board Fam Pract. 1993. PMID: 8452062 Clinical Trial.
METHODS: In this multipractice, office-based, randomized clinical trial, guaifenesin was compared with guaifenesin plus codeine or guaifenesin plus dextromethorphan in patients with uncomplicated respiratory tract infections. ...CONCLUSION: It appears …
METHODS: In this multipractice, office-based, randomized clinical trial, guaifenesin was compared with guaifenesin plus codein …
Evaluation of antitussive agents in man.
Parvez L, Vaidya M, Sakhardande A, Subburaj S, Rajagopalan TG. Parvez L, et al. Pulm Pharmacol. 1996 Oct-Dec;9(5-6):299-308. doi: 10.1006/pulp.1996.0039. Pulm Pharmacol. 1996. PMID: 9232667 Clinical Trial.
More recently, three studies evaluated the antitussive drug dextromethorphan in non-productive cough due to uncomplicated upper respiratory tract infections. ...
More recently, three studies evaluated the antitussive drug dextromethorphan in non-productive cough due to uncomplicated upper respi …
The Effects of Dextromethorphan on Driving Performance and the Standardized Field Sobriety Test.
Perry PJ, Fredriksen K, Chew S, Ip EJ, Lopes I, Doroudgar S, Thomas K. Perry PJ, et al. J Forensic Sci. 2015 Sep;60(5):1258-62. doi: 10.1111/1556-4029.12833. Epub 2015 Aug 21. J Forensic Sci. 2015. PMID: 26294136 Clinical Trial.
Dextromethorphan (DXM) is abused most commonly among adolescents as a recreational drug to generate a dissociative experience. ...The effects of one-time maximum daily doses of DXM 120 mg versus a guaifenesin 400 mg dose were compared among 40 healthy subjects using …
Dextromethorphan (DXM) is abused most commonly among adolescents as a recreational drug to generate a dissociative experience. ...The …
Bioavailability of dextromethorphan (as dextrorphan) from sustained release formulations in the presence of guaifenesin in human volunteers.
Demirbas S, Reyderman L, Stavchansky S. Demirbas S, et al. Biopharm Drug Dispos. 1998 Nov;19(8):541-5. doi: 10.1002/(sici)1099-081x(1998110)19:8<541::aid-bdd138>3.0.co;2-8. Biopharm Drug Dispos. 1998. PMID: 9840216 Clinical Trial.
The bioavailability of an experimental sustained release tablet containing dextromethorphan hydrobromide (DXP-HBr), was compared with a marketed sustained release DXP-HBr suspension in a three-way crossover study. ...Analysis of variance of the data revealed that the prese …
The bioavailability of an experimental sustained release tablet containing dextromethorphan hydrobromide (DXP-HBr), was compared with …