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Page 1
Drugs for cough.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2018 Dec 17;60(1562):206-208. Med Lett Drugs Ther. 2018. PMID: 30625123 Review. No abstract available.
Why Is Oral Phenylephrine on the Market After Compelling Evidence of Its Ineffectiveness as a Decongestant?
Hatton RC, Hendeles L. Hatton RC, et al. Ann Pharmacother. 2022 Mar 25:10600280221081526. doi: 10.1177/10600280221081526. Online ahead of print. Ann Pharmacother. 2022. PMID: 35337187
Despite solid research showing that oral phenylephrine is ineffective as a decongestant, the US Food and Drug Administration has failed to respond to a 2015 citizen's petition to remove it from the OTC nasal decongestant monograph. Other examples of scientifically proven i …
Despite solid research showing that oral phenylephrine is ineffective as a decongestant, the US Food and Drug Administration has fail …
Rapid screening and multicomponent quantifications of active components of oral syrup over-the-counter medications by Raman and UV-visible spectroscopy and multivariate regression analysis.
Fakayode SO, Bolton B, Dassow B, Galvez K, Chohan H. Fakayode SO, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2024 Jan 15;305:123447. doi: 10.1016/j.saa.2023.123447. Epub 2023 Sep 21. Spectrochim Acta A Mol Biomol Spectrosc. 2024. PMID: 37742594
PLS regressions of UV-visible absorption spectra were used for multicomponent quantifications of the active component (acetaminophen, guaifenesin, dextromethorphan HBr, and phenylephrine HCl) concentrations of OTMCs in flavored (sugar or sugar-free) oral syru …
PLS regressions of UV-visible absorption spectra were used for multicomponent quantifications of the active component (acetaminophen, gua …
Development and validation of a generic RP-HPLC PDA method for the simultaneous separation and quantification of active ingredients in cold and cough medicines.
Dongala T, Katari NK, Palakurthi AK, Jonnalagadda SB. Dongala T, et al. Biomed Chromatogr. 2019 Nov;33(11):e4641. doi: 10.1002/bmc.4641. Epub 2019 Aug 8. Biomed Chromatogr. 2019. PMID: 31265736
A novel generic reverse phase high performance liquid chromatography (RP-HPLC) method is developed and validated for simultaneous determination of seven pharmaceutically active ingredients, namely, acetaminophen, dextromethorphan, doxylamine, phenylephrine, guaif …
A novel generic reverse phase high performance liquid chromatography (RP-HPLC) method is developed and validated for simultaneous determinat …
Safety Profile of Cough and Cold Medication Use in Pediatrics.
Green JL, Wang GS, Reynolds KM, Banner W, Bond GR, Kauffman RE, Palmer RB, Paul IM, Dart RC. Green JL, et al. Pediatrics. 2017 Jun;139(6):e20163070. doi: 10.1542/peds.2016-3070. Epub 2017 May 4. Pediatrics. 2017. PMID: 28562262
METHODS: Cases with adverse events (AEs) after ingestion of at least 1 index CCM ingredient (brompheniramine, chlorpheniramine, dextromethorphan, diphenhydramine, doxylamine, guaifenesin, phenylephrine, and pseudoephedrine) in children <12 years of age wer …
METHODS: Cases with adverse events (AEs) after ingestion of at least 1 index CCM ingredient (brompheniramine, chlorpheniramine, dextromet …
Assessment of Pharmacologic Ingredients in Common Over-the-Counter Sinonasal Medications.
McCoul ED. McCoul ED. JAMA Otolaryngol Head Neck Surg. 2020 Sep 1;146(9):810-815. doi: 10.1001/jamaoto.2020.1836. JAMA Otolaryngol Head Neck Surg. 2020. PMID: 32672802 Free PMC article.
Only 8 unique nonanalgesic ingredients were identified among these products, with many products sold under the same brand name and with the same active ingredient. Phenylephrine hydrochloride, dextromethorphan hydrobromide, pseudoephedrine hydrochloride, guaifene …
Only 8 unique nonanalgesic ingredients were identified among these products, with many products sold under the same brand name and with the …
Development and validation of a generic high-performance liquid chromatography for the simultaneous separation and determination of six cough ingredients: Robustness study on core-shell particles.
Yehia AM, Essam HM. Yehia AM, et al. J Sep Sci. 2016 Sep;39(17):3357-67. doi: 10.1002/jssc.201600438. Epub 2016 Aug 11. J Sep Sci. 2016. PMID: 27404374
A generally applicable high-performance liquid chromatographic method for the qualitative and quantitative determination of pharmaceutical preparations containing phenylephrine hydrochloride, paracetamol, ephedrine hydrochloride, guaifenesin, doxylamine succinate, a …
A generally applicable high-performance liquid chromatographic method for the qualitative and quantitative determination of pharmaceutical p …
Ion mobility spectrometry for the rapid analysis of over-the-counter drugs and beverages.
Fernández-Maestre R, Hill HH. Fernández-Maestre R, et al. Int J Ion Mobil Spectrom. 2009 Aug;12(3):91-102. doi: 10.1007/s12127-009-0025-x. Epub 2009 Jul 1. Int J Ion Mobil Spectrom. 2009. PMID: 20835390 Free PMC article.
The active ingredients determined in drugs were acetaminophen, aspartame, bisacodyl, caffeine, dextromethorphan, diphenhydramine, famotidine, glucosamine, guaifenesin, loratadine, niacin, phenylephrine, pyridoxine, thiamin, and tetrahydrozoline. ...
The active ingredients determined in drugs were acetaminophen, aspartame, bisacodyl, caffeine, dextromethorphan, diphenhydramine, fam …