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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 3
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1977 10
1978 20
1979 21
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1981 18
1982 13
1983 14
1984 19
1985 19
1986 27
1987 22
1988 25
1989 36
1990 45
1991 41
1992 50
1993 70
1994 55
1995 55
1996 76
1997 65
1998 65
1999 62
2000 69
2001 59
2002 72
2003 58
2004 97
2005 89
2006 79
2007 80
2008 72
2009 85
2010 87
2011 82
2012 77
2013 80
2014 70
2015 78
2016 74
2017 72
2018 45
2019 42
2020 38
2021 33
2022 32
2023 27
2024 28
2025 36
2026 7

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2,344 results

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Page 1
Diclofenac.
Ogle C. Ogle C. Conn Med. 1989 Oct;53(10):603-4. Conn Med. 1989. PMID: 2684502 Clinical Trial.
Diclofenac is the newest NSAID to be introduced to the United States. Extensive worldwide clinical studies with diclofenac have demonstrated its efficacy in the treatment of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Its overall safety and eff …
Diclofenac is the newest NSAID to be introduced to the United States. Extensive worldwide clinical studies with diclofenac hav …
Oral omeprazole and diclofenac intake is associated with increased faecal calprotectin levels: a randomised open-label clinical trial.
Rendek Z, Falk M, Grodzinsky E, Kechagias S, Hjortswang H. Rendek Z, et al. Eur J Gastroenterol Hepatol. 2023 Jan 1;35(1):52-58. doi: 10.1097/MEG.0000000000002473. Epub 2022 Nov 7. Eur J Gastroenterol Hepatol. 2023. PMID: 36468569 Free article. Clinical Trial.
RESULTS: Thirty-two healthy volunteers were included. During drug intake, 39% on diclofenac (median 70.8 g/g; range 50.2-1080 g/g), 53% on omeprazole (median 85.3 g/g; range 51.1-249 g/g) and 69% on omeprazole + diclofenac (median 101.5 g/g; range 51.5-532 g/g) had …
RESULTS: Thirty-two healthy volunteers were included. During drug intake, 39% on diclofenac (median 70.8 g/g; range 50.2-1080 g/g), 5 …
Comparative clinical trial of castor oil and diclofenac sodium in patients with osteoarthritis.
Medhi B, Kishore K, Singh U, Seth SD. Medhi B, et al. Phytother Res. 2009 Oct;23(10):1469-73. doi: 10.1002/ptr.2804. Phytother Res. 2009. PMID: 19288533 Clinical Trial.
A randomized, double-blind, comparative clinical study was conducted to compare the safety and efficacy of castor oil with diclofenac sodium in patients with knee osteoarthritis. Subjects with symptoms of knee osteoarthritis were given a castor oil capsule 0.9 mL (n = 50) …
A randomized, double-blind, comparative clinical study was conducted to compare the safety and efficacy of castor oil with diclofenac …
Randomized, controlled clinical trial of safety and plasma concentrations of diclofenac in healthy neonatal foals after repeated topical application of 1% diclofenac sodium cream.
Barnett SE, Sellon DC, Hines MT, Seino KK, Knych HK. Barnett SE, et al. Am J Vet Res. 2017 Apr;78(4):405-411. doi: 10.2460/ajvr.78.4.405. Am J Vet Res. 2017. PMID: 28346003 Free article. Clinical Trial.
Venous blood samples were collected at predefined intervals following application of the diclofenac cream, and plasma diclofenac concentrations were determined by liquid chromatography-mass spectrometry. ...Plasma diclofenac concentrations peaked rapidly foll …
Venous blood samples were collected at predefined intervals following application of the diclofenac cream, and plasma diclofenac …
Diclofenac.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 1988 Dec 2;30(780):109-11. Med Lett Drugs Ther. 1988. PMID: 3054450 Clinical Trial. No abstract available.
Overall safety of Arthrotec.
Geis GS. Geis GS. Scand J Rheumatol Suppl. 1992;96:33-6. Scand J Rheumatol Suppl. 1992. PMID: 1439622 Clinical Trial.
For 4 to 12 weeks, 747 patients received Arthrotec, a combination of 50 mg of diclofenac and 200 micrograms of misoprostol, and 754 patients received 50 mg of diclofenac; the drugs were given twice or three times daily. ...Serious adverse events occurred in eight of …
For 4 to 12 weeks, 747 patients received Arthrotec, a combination of 50 mg of diclofenac and 200 micrograms of misoprostol, and 754 p …
Review of the safety of diclofenac/misoprostol.
Gagnier P. Gagnier P. Drugs. 1993;45 Suppl 1:31-5. doi: 10.2165/00003495-199300451-00008. Drugs. 1993. PMID: 7685686 Review.
Short term trials have been conducted in patients with osteoarthritis (n = 1032) and rheumatoid arthritis (n = 685) over 1 or 3 months. Patients randomly received either diclofenac alone or diclofenac/misoprostol. In both groups, the most frequently reported adverse …
Short term trials have been conducted in patients with osteoarthritis (n = 1032) and rheumatoid arthritis (n = 685) over 1 or 3 months. Pati …
Diclofenac and oxycodone in treatment of postoperative pain: a double-blind trial.
Nuutinen LS, Wuolijoki E, Pentikäinen IT. Nuutinen LS, et al. Acta Anaesthesiol Scand. 1986 Nov;30(8):620-4. doi: 10.1111/j.1399-6576.1986.tb02487.x. Acta Anaesthesiol Scand. 1986. PMID: 3544648 Clinical Trial.
Patients requesting an analgesic were given either 75 mg of diclofenac or 10 mg of oxycodone as an intramuscular injection. The onset of analgesic effect occurred within 13 +/- 4 min with oxycodone and within 16 +/- 8 min with diclofenac. ...Side-effects: 21 patient …
Patients requesting an analgesic were given either 75 mg of diclofenac or 10 mg of oxycodone as an intramuscular injection. The onset …
Penetration of topical diclofenac sodium 4 % spray gel into the synovial tissue and synovial fluid of the knee: a randomised clinical trial.
Efe T, Sagnak E, Roessler PP, Getgood A, Patzer T, Fuchs-Winkelmann S, Peterlein CD, Schofer MD. Efe T, et al. Knee Surg Sports Traumatol Arthrosc. 2014 Feb;22(2):345-50. doi: 10.1007/s00167-013-2408-0. Epub 2013 Jan 22. Knee Surg Sports Traumatol Arthrosc. 2014. PMID: 23338668 Clinical Trial.
METHODS: A total of 39 patients were randomised to two- or three-times daily application of diclofenac sodium 4 % spray gel to knees requiring surgery over a treatment period of 3 days. Within 8 h after the last application, TKA was conducted, and the diclofenac con …
METHODS: A total of 39 patients were randomised to two- or three-times daily application of diclofenac sodium 4 % spray gel to knees …
Penetration of topically applied diclofenac and ketorolac into the aqueous humour and subretinal fluid: randomized clinical trial.
Unlu N, Kocaoglan H, Sayin F, Hazirolan D, Demircan S, Basci N, Acar MA, Demir NM, Duman S. Unlu N, et al. Can J Ophthalmol. 2010 Dec;45(6):610-5. doi: 10.3129/i10-048. Can J Ophthalmol. 2010. PMID: 20935692 Clinical Trial.
OBJECTIVE: To determine the level of intraocular penetration of diclofenac sodium and ketorolac tromethamine into the aqueous humour and subretinal fluid. ...Aqueous humour concentrations of ketorolac were higher than those of diclofenac (p = 0.019). CONCLUSIONS: Th …
OBJECTIVE: To determine the level of intraocular penetration of diclofenac sodium and ketorolac tromethamine into the aqueous humour …
2,344 results