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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 6
1981 9
1982 19
1983 19
1984 20
1985 48
1986 42
1987 55
1988 50
1989 65
1990 67
1991 79
1992 64
1993 45
1994 61
1995 68
1996 52
1997 52
1998 44
1999 36
2000 29
2001 33
2002 24
2003 21
2004 16
2005 18
2006 13
2007 12
2008 11
2009 16
2010 14
2011 8
2012 12
2013 16
2014 13
2015 13
2016 12
2017 8
2018 6
2019 5
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2021 7
2022 3
2023 1

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1,193 results

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Page 1
Effect of diltiazem on exercise tolerance in patients with stable coronary artery disease and hypertension.
Peng X, Peng DF, Tang SY. Peng X, et al. J Physiol Pharmacol. 2021 Aug;72(4). doi: 10.26402/jpp.2021.4.07. Epub 2021 Dec 31. J Physiol Pharmacol. 2021. PMID: 34987129 Free article. Clinical Trial.

The present study aimed to investigate the effect of diltiazem on cardiovascular risk and exercise tolerance in patients with stable coronary artery disease and hypertension. From 2016 to 2018, 80 patients with stable coronary artery disease (5 < Gensini score < 20)

…
The present study aimed to investigate the effect of diltiazem on cardiovascular risk and exercise tolerance in patients with stable …
Calcium-channel blocking agents.
Leonard RG, Talbert RL. Leonard RG, et al. Clin Pharm. 1982 Jan-Feb;1(1):17-33. Clin Pharm. 1982. PMID: 6764159 Review.
Diltiazem's oral bioavailability is good (90% reaches systemic circulation), but there is significant interindividual variability between administered dose and resulting plasma concentration. Geriatric patients have delayed absorption and reduced clearance of diltiazem …
Diltiazem's oral bioavailability is good (90% reaches systemic circulation), but there is significant interindividual variability bet …
An assessment of diltiazem and hydrochlorothiazide in hypertension. Application of factorial trial design to a multicenter clinical trial of combination therapy.
Burris JF, Weir MR, Oparil S, Weber M, Cady WJ, Stewart WH. Burris JF, et al. JAMA. 1990 Mar 16;263(11):1507-12. JAMA. 1990. PMID: 2407872 Clinical Trial.
After a 4- to 6-week placebo run-in period, 297 qualifying patients were randomized to receive placebo, 1 of 4 doses of diltiazem SR monotherapy, 1 of 3 doses of hydrochlorothiazide monotherapy, or 1 of 12 possible combinations of diltiazem SR and hydrochlorothiazid …
After a 4- to 6-week placebo run-in period, 297 qualifying patients were randomized to receive placebo, 1 of 4 doses of diltiazem SR …
Design of a placebo-controlled clinical trial of long-acting diltiazem and aspirin versus aspirin alone in patients receiving thrombolysis with a first acute myocardial infarction. Incomplete Infarction Trial of European Research Collaborators Evaluating Prognosis Post-Thrombolysis (diltiazem) (INTERCEPT) Research Group.
Boden WE, Scheldewaert R, Walters EG, Whitehead A, Coltart DJ, Santoni JP, Belgrave G, Starkey IR. Boden WE, et al. Am J Cardiol. 1995 Jun 1;75(16):1120-3. doi: 10.1016/s0002-9149(99)80742-5. Am J Cardiol. 1995. PMID: 7762497 Clinical Trial.
Although calcium antagonists have not been shown to alter post-AMI mortality, diltiazem has been shown to reduce recurrent nonfatal infarction and myocardial ischemia following non-Q-wave AMI. ...We have initiated a multicenter, randomized, placebo-controlled, double-blind …
Although calcium antagonists have not been shown to alter post-AMI mortality, diltiazem has been shown to reduce recurrent nonfatal i …
Randomized clinical trial assessing the side-effects of glyceryl trinitrate and diltiazem hydrochloride in the treatment of chronic anal fissure.
Kocher HM, Steward M, Leather AJ, Cullen PT. Kocher HM, et al. Br J Surg. 2002 Apr;89(4):413-7. doi: 10.1046/j.0007-1323.2001.02042.x. Br J Surg. 2002. PMID: 11952579 Clinical Trial.
INTRODUCTION: Glyceryl trinitrate (GTN) ointment (0 small middle dot2 per cent) has an efficacy of up to 68 per cent in healing chronic anal fissure, but with headache as a major side-effect. Diltiazem hydrochloride (DTZ) cream (2 per cent) is expected to have fewer side-e …
INTRODUCTION: Glyceryl trinitrate (GTN) ointment (0 small middle dot2 per cent) has an efficacy of up to 68 per cent in healing chronic anal …
Antihypertensive safety and efficacy and physician and patient satisfaction: results from a phase 4 practice-based clinical experience trial with diltiazem LA.
Glasser SP. Glasser SP. Adv Ther. 2006 Mar-Apr;23(2):284-94. doi: 10.1007/BF02850134. Adv Ther. 2006. PMID: 16751161 Clinical Trial.
This study was undertaken to assess the safety and efficacy of a new long-acting formulation of diltiazem (DLA) (Cardizem LA; Biovail Pharmaceuticals, Inc., Bridgewater, NJ) in a large heterogeneous group of hypertensive patients, and to evaluate physician and patient trea …
This study was undertaken to assess the safety and efficacy of a new long-acting formulation of diltiazem (DLA) (Cardizem LA; Biovail …
Gallopamil and diltiazem: a double-blind, randomized, cross-over trial in effort ischaemia.
Marraccini P, Orsini E, Brunelli C, Nassi G, Ghigliotti G, Iannetti M, Caponnetto S, L'Abbate A. Marraccini P, et al. Eur Heart J. 1992 Mar;13(3):404-10. doi: 10.1093/oxfordjournals.eurheartj.a060181. Eur Heart J. 1992. PMID: 1597229 Clinical Trial.
The aim of this study was to evaluate the efficacy and possibly the mechanism of action of gallopamil and diltiazem in a double-blind crossover trial in patients with effort ischaemia. ...Individual analysis showed that 13/20 patients under gallopamil and 13/20 under di …
The aim of this study was to evaluate the efficacy and possibly the mechanism of action of gallopamil and diltiazem in a double-blind …
The diltiazem-digoxin interaction.
Rameis H, Magometschnigg D, Ganzinger U. Rameis H, et al. Clin Pharmacol Ther. 1984 Aug;36(2):183-9. doi: 10.1038/clpt.1984.160. Clin Pharmacol Ther. 1984. PMID: 6744777 Clinical Trial.
Diltiazem with digoxin induced an average increase of steady-state plasma digoxin concentration and AUC over 48 hr of 22.4%. ...Apparent volume of distribution was not relevantly altered. Diltiazem kinetics did not change significantly when digoxin was concurrently …
Diltiazem with digoxin induced an average increase of steady-state plasma digoxin concentration and AUC over 48 hr of 22.4%. ...Appar …
Clinical utility of nifedipine and diltiazem plasma levels in patients with angina pectoris receiving monotherapy and combination treatment.
Goldberger J, Frishman WH. Goldberger J, et al. J Clin Pharmacol. 1989 Jul;29(7):628-34. doi: 10.1002/j.1552-4604.1989.tb03391.x. J Clin Pharmacol. 1989. PMID: 2760256 Clinical Trial.
The clinical utility of nifedipine and diltiazem blood levels in patients with angina pectoris receiving monotherapy (N = 14) and combination treatment (N = 9) were assessed in a placebo run-in, double blind, randomized, crossover study. Compared to placebo, diltiazem …
The clinical utility of nifedipine and diltiazem blood levels in patients with angina pectoris receiving monotherapy (N = 14) and com …
Pharmacokinetic and pharmacodynamic interactions between diltiazem and methylprednisolone in healthy volunteers.
Booker BM, Magee MH, Blum RA, Lates CD, Jusko WJ. Booker BM, et al. Clin Pharmacol Ther. 2002 Oct;72(4):370-82. doi: 10.1067/mcp.2002.127944. Clin Pharmacol Ther. 2002. PMID: 12386639 Clinical Trial.
The AUC of diltiazem was unchanged in the presence of methylprednisolone. No significant intrinsic pharmacodynamic differences were observed for methylprednisolone versus methylprednisolone-diltiazem. ...However, significant differences between 50% inhibitory concen …
The AUC of diltiazem was unchanged in the presence of methylprednisolone. No significant intrinsic pharmacodynamic differences were o …
1,193 results