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Final report on the safety assessment of stearoxy dimethicone, dimethicone, methicone, amino bispropyl dimethicone, aminopropyl dimethicone, amodimethicone, amodimethicone hydroxystearate, behenoxy dimethicone, C24-28 alkyl methicone, C30-45 alkyl methicone, C30-45 alkyl dimethicone, cetearyl methicone, cetyl dimethicone, dimethoxysilyl ethylenediaminopropyl dimethicone, hexyl methicone, hydroxypropyldimethicone, stearamidopropyl dimethicone, stearyl dimethicone, stearyl methicone, and vinyldimethicone.
Nair B; Cosmetic Ingredients Review Expert Panel. Nair B, et al. Int J Toxicol. 2003;22 Suppl 2:11-35. Int J Toxicol. 2003. PMID: 14555417 Review.
Methicone is a linear monomethyl polysiloxane. The other dimethicones and methicones covered in this review are siloxane polymers of Dimethicone and Methicone. ...Accordingly, the CIR Expert Panel was of the opinion that Stearoxy Dimethicone, Dimethicone
Methicone is a linear monomethyl polysiloxane. The other dimethicones and methicones covered in this review are siloxane polymers of …
Safety and efficacy of a 100% dimethicone pediculocide in school-age children.
Ihde ES, Boscamp JR, Loh JM, Rosen L. Ihde ES, et al. BMC Pediatr. 2015 Jun 20;15:70. doi: 10.1186/s12887-015-0381-0. BMC Pediatr. 2015. PMID: 26092045 Free PMC article.
Concerns exist about the safety and efficacy of pesticide-based treatments. Published studies suggest dimethicone is a potentially safe and effective non-toxic treatment, but have not evaluated 100% dimethicone in a pediatric population. ...Because dimethicone
Concerns exist about the safety and efficacy of pesticide-based treatments. Published studies suggest dimethicone is a potentially sa …
Compounding with Silicones.
Allen LV Jr. Allen LV Jr. Int J Pharm Compd. 2015 May-Jun;19(3):223-30. Int J Pharm Compd. 2015. PMID: 26714363 Review.
In addition is their use for "siliconization," or surface treatment, of many parenteral packaging components. Dimethicone and silicone oil are used as lubricants on stoppers to aid machineability, in syringes to aid piston movement, or on syringe needles to reduce pain upo …
In addition is their use for "siliconization," or surface treatment, of many parenteral packaging components. Dimethicone and silicon …
Effect of dimethicone (polysilane gel) on the stereoselective pharmacokinetics of ketoprofen.
Presle N, Lapicque F, Gillet P, Herrmann MA, Bannwarth B, Netter P. Presle N, et al. Eur J Clin Pharmacol. 1998 Jun;54(4):351-4. doi: 10.1007/s002280050473. Eur J Clin Pharmacol. 1998. PMID: 9696963 Clinical Trial.
Nevertheless, the urinary recovery was significantly lower for R ketoprofen than for its antipode. The administration of dimethicone did not alter this stereoselectivity. CONCLUSION: The administration of dimethicone to alleviate the epigastralgic effects related to …
Nevertheless, the urinary recovery was significantly lower for R ketoprofen than for its antipode. The administration of dimethicone
Development and Characterization of A New Dimethicone Nanoemulsion and its Application for Electronic Gastroscopy Examination.
Feng SM, Zhao Y, Xu Q, Li HM, Huang YX, Liu HH, Xu CB. Feng SM, et al. Int J Nanomedicine. 2020 Jul 29;15:5405-5416. doi: 10.2147/IJN.S251113. eCollection 2020. Int J Nanomedicine. 2020. PMID: 32801696 Free PMC article. Clinical Trial.
PURPOSE: Although the effective and safe medical defoamers, dimethicone (DM) and simethicone (SM) are widely used in electronic gastroscope examination (EGE), their preparations are presented in the form of suspensions or emulsions, these are untransparent or milk-like in …
PURPOSE: Although the effective and safe medical defoamers, dimethicone (DM) and simethicone (SM) are widely used in electronic gastr …
Assessment of Efficacy and Irritation of Ingenol Mebutate Gel 0.015% Used With or Without Dimethicone Lotion for Treatment of Actinic Keratosis on the Face.
Jim On SC, Hashim PW, Nia JK, Lebwohl MG. Jim On SC, et al. J Drugs Dermatol. 2017 May 1;16(5):432-436. J Drugs Dermatol. 2017. PMID: 28628678

Objective: This study sought to determine whether the application of 1% dimethicone would decrease ingenol mebutate-associated LSRs and/or affect efficacy during the treatment of multiple AKs on the face....</p> <p>Limitations: The study eva …

Objective: This study sought to determine whether the application of 1% dimethicone would decrease ingenol mebuta …

Use of dimethicone to reduce the fall in gastric potential difference induced by bile salts.
Bergmann JF, Simoneau G, Chantelair G, Caulin C, Segrestaa JM. Bergmann JF, et al. Eur J Clin Pharmacol. 1989;36(4):379-81. doi: 10.1007/BF00558299. Eur J Clin Pharmacol. 1989. PMID: 2737231 Clinical Trial.
The gastric potential difference (PD) was measured in ten healthy volunteers after sodium taurocholate intake. This bile salt was given after treatment with dimethicone or placebo in a cross-over design study. With dimethicone the fall in PD was lower …
The gastric potential difference (PD) was measured in ten healthy volunteers after sodium taurocholate intake. This bile salt was giv …
Dimethicone barrier cream prevents infection of human skin by schistosome cercariae: evidence from Franz cell studies.
Ingram RJ, Bartlett A, Brown MB, Marriott C, Whiffield RJ. Ingram RJ, et al. J Parasitol. 2002 Apr;88(2):399-402. doi: 10.1645/0022-3395(2002)088[0399:DBCPIO]2.0.CO;2. J Parasitol. 2002. PMID: 12054019
The results show that a single application of a barrier cream based on dimethicone offers a high level of protection against penetration that is sustained for at least 48 hr....
The results show that a single application of a barrier cream based on dimethicone offers a high level of protection against penetrat …
113 results