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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 2
1967 8
1968 6
1969 6
1970 7
1971 8
1972 2
1973 9
1974 3
1975 7
1976 7
1977 6
1978 7
1979 6
1980 6
1981 5
1982 6
1983 4
1984 6
1985 12
1986 9
1987 15
1988 11
1989 12
1990 12
1991 22
1992 18
1993 24
1994 28
1995 29
1996 31
1997 20
1998 19
1999 18
2000 24
2001 17
2002 17
2003 16
2004 14
2005 10
2006 25
2007 19
2008 20
2009 11
2010 15
2011 15
2012 14
2013 12
2014 7
2015 11
2016 8
2017 16
2018 8
2019 14
2020 8
2021 9
2022 5
2023 5
2024 3

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679 results

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Page 1
Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial.
Sio TT, Le-Rademacher JG, Leenstra JL, Loprinzi CL, Rine G, Curtis A, Singh AK, Martenson JA Jr, Novotny PJ, Tan AD, Qin R, Ko SJ, Reiter PL, Miller RC. Sio TT, et al. JAMA. 2019 Apr 16;321(15):1481-1490. doi: 10.1001/jama.2019.3504. JAMA. 2019. PMID: 30990550 Free PMC article. Clinical Trial.
In a randomized study, doxepin mouthwash was shown to reduce oral mucositis-related pain. A common mouthwash comprising diphenhydramine-lidocaine-antacid is also widely used. OBJECTIVE: To evaluate the effect of doxepin mouthwash or diphenhydramine-lidocaine-antacid …
In a randomized study, doxepin mouthwash was shown to reduce oral mucositis-related pain. A common mouthwash comprising diphenhydramine
Valerian-hops combination and diphenhydramine for treating insomnia: a randomized placebo-controlled clinical trial.
Morin CM, Koetter U, Bastien C, Ware JC, Wooten V. Morin CM, et al. Sleep. 2005 Nov;28(11):1465-71. doi: 10.1093/sleep/28.11.1465. Sleep. 2005. PMID: 16335333 Clinical Trial.
There were no significant residual effects and no serious adverse events with either valerian or diphenhydramine and no rebound insomnia following their discontinuation. ...Overall, these findings indicate that a valerian-hops combination and diphenhydramine might b …
There were no significant residual effects and no serious adverse events with either valerian or diphenhydramine and no rebound insom …
Psilocybin for alcohol use disorder: Rationale and design considerations for a randomized controlled trial.
O'Donnell KC, Mennenga SE, Owens LT, Podrebarac SK, Baron T, Rotrosen J, Ross S, Forcehimes AA, Bogenschutz MP. O'Donnell KC, et al. Contemp Clin Trials. 2022 Dec;123:106976. doi: 10.1016/j.cct.2022.106976. Epub 2022 Nov 2. Contemp Clin Trials. 2022. PMID: 36332827 Clinical Trial.
In addition to a structured 12-week psychotherapy platform, participants (n = 96) were randomly assigned (1:1) to receive either oral psilocybin or an active placebo (oral diphenhydramine) in each of two dosing sessions (at weeks 4 and 8). Initial doses were 25 mg/70 kg ps …
In addition to a structured 12-week psychotherapy platform, participants (n = 96) were randomly assigned (1:1) to receive either oral psiloc …
Sedative effects of antihistamines.
Roth T, Roehrs T, Koshorek G, Sicklesteel J, Zorick F. Roth T, et al. J Allergy Clin Immunol. 1987 Jul;80(1):94-8. doi: 10.1016/s0091-6749(87)80197-5. J Allergy Clin Immunol. 1987. PMID: 2885356 Clinical Trial.
Each day, the drug or placebo was administered at 8 A.M. and 12 and 4 P.M. Diphenhydramine was administered in three equal doses (50 mg), and loratadine was administered in a single dose followed by two placebo doses. Mean latency to sleep on tests done at 9 and 11 A.M. an …
Each day, the drug or placebo was administered at 8 A.M. and 12 and 4 P.M. Diphenhydramine was administered in three equal doses (50 …
Nelson's eye.
[No authors listed] [No authors listed] Lancet. 1979 Jun 16;1(8129):1280. Lancet. 1979. PMID: 87735 Clinical Trial. No abstract available.
Pharmacodynamic response profiles of anxiolytic and sedative drugs.
Chen X, Broeyer F, de Kam M, Baas J, Cohen A, van Gerven J. Chen X, et al. Br J Clin Pharmacol. 2017 May;83(5):1028-1038. doi: 10.1111/bcp.13204. Epub 2017 Mar 17. Br J Clin Pharmacol. 2017. PMID: 27922194 Free PMC article. Clinical Trial.
RESULTS: Compared to placebo, VAS(calmness) increased with alprazolam (2.0 mm) and pregabalin (2.5 mm) but not with diphenhydramine. Saccadic peak velocity (SPV) declined after alprazolam (-57 s(-1) ) and pregabalin (-28 s(-1) ), more than with diphenhydramine (-14 …
RESULTS: Compared to placebo, VAS(calmness) increased with alprazolam (2.0 mm) and pregabalin (2.5 mm) but not with diphenhydramine. …
Diphenhydramine as Adjuvant Therapy for Acute Migraine: An Emergency Department-Based Randomized Clinical Trial.
Friedman BW, Cabral L, Adewunmi V, Solorzano C, Esses D, Bijur PE, Gallagher EJ. Friedman BW, et al. Ann Emerg Med. 2016 Jan;67(1):32-39.e3. doi: 10.1016/j.annemergmed.2015.07.495. Epub 2015 Aug 29. Ann Emerg Med. 2016. PMID: 26320523 Free PMC article. Clinical Trial.
One hour after medication administration, patients randomized to diphenhydramine improved by a mean of 5.1 on the 0 to 10 scale versus 4.8 for those randomized to placebo (95% CI for difference of 0.3: -0.6 to 1.1). ...Median ED length of stay was 122 minutes (interquartil …
One hour after medication administration, patients randomized to diphenhydramine improved by a mean of 5.1 on the 0 to 10 scale versu …
Randomized Trial of Adding Parenteral Acetaminophen to Prochlorperazine and Diphenhydramine to Treat Headache in the Emergency Department.
Meyering SH, Stringer RW, Hysell MK. Meyering SH, et al. West J Emerg Med. 2017 Apr;18(3):373-381. doi: 10.5811/westjem.2016.12.29218. Epub 2017 Feb 27. West J Emerg Med. 2017. PMID: 28435487 Free PMC article. Clinical Trial.
Secondary outcomes measures included assessment of decreased requirement of "rescue" pain medicines, defined as any analgesic medications outside of diphenhydramine, prochlorperazine and acetaminophen, with particular interest to potential opioid-sparing effects with paren …
Secondary outcomes measures included assessment of decreased requirement of "rescue" pain medicines, defined as any analgesic medications ou …
The effects of licorice containing diphenhydramine solution on recurrent aphthous stomatitis: A double-blind, randomized clinical trial.
Akbari N, Asadimehr N, Kiani Z. Akbari N, et al. Complement Ther Med. 2020 May;50:102401. doi: 10.1016/j.ctim.2020.102401. Epub 2020 Apr 15. Complement Ther Med. 2020. PMID: 32444056 Clinical Trial.
OBJECTIVES: The aim of this study was to compare the efficacy of the diphenhydramine solution (DS) and diphenhydramine-containing glycyrrhiza glabra (DSG) in the treatment of recurrent aphthous stomatitis (RAS). ...INTERVENTION: DSG was made by adding 5% hydroethano …
OBJECTIVES: The aim of this study was to compare the efficacy of the diphenhydramine solution (DS) and diphenhydramine-contain …
Efficacy of SM-1 in a transient insomnia model.
Dahl T, Chen LB, Zammit G, Ahmad M, Roth T. Dahl T, et al. Hum Psychopharmacol. 2019 Nov;34(6):e2713. doi: 10.1002/hup.2713. Hum Psychopharmacol. 2019. PMID: 31837050 Clinical Trial.
WASO, sTST, sleep quality, and sSL also showed significant improvement. Diphenhydramine demonstrated a significant (p = .014) contribution of 43.7 min to TST. ...CONCLUSIONS: SM-1 provided a robust and statistically significant increase in TST compared with placebo in a ci …
WASO, sTST, sleep quality, and sSL also showed significant improvement. Diphenhydramine demonstrated a significant (p = .014) contrib …
679 results