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Page 1
Randomized clinical trial of docusate, triethanolamine polypeptide, and irrigation in cerumen removal in children.
Whatley VN, Dodds CL, Paul RI. Whatley VN, et al. Arch Pediatr Adolesc Med. 2003 Dec;157(12):1177-80. doi: 10.1001/archpedi.157.12.1177. Arch Pediatr Adolesc Med. 2003. PMID: 14662569 Clinical Trial.
There was no significant difference in the proportion of tympanic membranes completely visualized after treatment with docusate (18/34; 53%), triethanolamine polypeptide (13/30; 43%), or saline (19/28; 68%) (P =.17). CONCLUSION: Application of docusate sodium or tri …
There was no significant difference in the proportion of tympanic membranes completely visualized after treatment with docusate (18/3 …
Polyethylene Glycol 3350 and Docusate Sodium Compared With Docusate Sodium Alone After Urogynecologic Surgery: A Randomized Controlled Trial.
Edenfield AL, Siddiqui NY, Wu JM, Dieter AA, Garrett MA, Visco AG. Edenfield AL, et al. Obstet Gynecol. 2016 Sep;128(3):543-9. doi: 10.1097/AOG.0000000000001565. Obstet Gynecol. 2016. PMID: 27500338 Clinical Trial.
OBJECTIVE: To compare time to first bowel movement and additional gastrointestinal outcomes between women receiving polyethylene glycol 3350 (PEG3350) and docusate sodium and docusate sodium alone after urogynecologic surgery. METHODS: Participants received twice-da …
OBJECTIVE: To compare time to first bowel movement and additional gastrointestinal outcomes between women receiving polyethylene glycol 3350 …
Randomized, double-blind, placebo-controlled trial of oral docusate in the management of constipation in hospice patients.
Tarumi Y, Wilson MP, Szafran O, Spooner GR. Tarumi Y, et al. J Pain Symptom Manage. 2013 Jan;45(1):2-13. doi: 10.1016/j.jpainsymman.2012.02.008. Epub 2012 Aug 11. J Pain Symptom Manage. 2013. PMID: 22889861 Free article. Clinical Trial.
CONTEXT: The stool softener docusate is widely used in the management of constipation in hospice patients. ...Docusate use should be considered on an individual basis....
CONTEXT: The stool softener docusate is widely used in the management of constipation in hospice patients. ...Docusate use sho …
Cerumenolytic Efficacy of 2.5% Sodium Bicarbonate Versus Docusate Sodium: A Randomized, Controlled Trial.
Piromchai P, Laohakittikul C, Khunnawongkrit S, Srirompotong S. Piromchai P, et al. Otol Neurotol. 2020 Aug;41(7):e842-e847. doi: 10.1097/MAO.0000000000002672. Otol Neurotol. 2020. PMID: 32658399 Clinical Trial.
OBJECTIVES: To evaluate the efficacy of 2.5% sodium bicarbonate and docusate sodium in patients with complete occlusion of the ear canal from impacted cerumen. ...CONCLUSION: 2.5% sodium bicarbonate demonstrated non-inferior efficacy and safety compared with docusate
OBJECTIVES: To evaluate the efficacy of 2.5% sodium bicarbonate and docusate sodium in patients with complete occlusion of the ear ca …
The efficacy of docusate sodium and senna glycoside for the treatment of constipation after rotator cuff repair: A randomized controlled study.
Weekes DG, Campbell RE, Giunta NJ, Pepe MD, Tucker BS, Londahl-Ramsey VE, Tjoumakaris FP. Weekes DG, et al. J Am Assoc Nurse Pract. 2021 Feb 18;34(1):62-69. doi: 10.1097/JXX.0000000000000575. J Am Assoc Nurse Pract. 2021. PMID: 33625162 Clinical Trial.
METHODS: Patients (n = 107) were randomized to receive docusate sodium, senna glycoside, or nothing (control) in addition to a standardized postoperative protocol. ...There was no difference in the prevalence of constipation in the docusate, senna, and control group …
METHODS: Patients (n = 107) were randomized to receive docusate sodium, senna glycoside, or nothing (control) in addition to a standa …
[A Randomized, Double-blind, Active-controlled Exploratory Clinical Trial for the Evaluation of the Efficacy and Safety of Goodmorning S Granule® on Constipation].
Ju M, Kim N, Shin CM, Park YS, Yoon H, Choi Y, Lee DH. Ju M, et al. Korean J Gastroenterol. 2022 Jul 25;80(1):17-27. doi: 10.4166/kjg.2022.025. Korean J Gastroenterol. 2022. PMID: 35879059 Free article. Clinical Trial. Korean.
BACKGROUND/AIMS: Constipation is a common gastrointestinal disease that reduces the quality of life and incurs considerable medical expenses. Bisacodyl and sodium docusate are generally used to treat constipation. This study assessed the effectiveness and safety of Goodmor …
BACKGROUND/AIMS: Constipation is a common gastrointestinal disease that reduces the quality of life and incurs considerable medical expenses …
The relative bioavailability of paracetamol and codeine after oral administration of a combination of buclizine, paracetamol and codeine, with or without docusate, and of paracetamol alone in healthy volunteers.
Persaud N, Johnson ES, Merrington D, Oliver W. Persaud N, et al. Curr Med Res Opin. 1985;9(9):626-33. doi: 10.1185/03007998509109644. Curr Med Res Opin. 1985. PMID: 2414066 Clinical Trial.
A randomized, double-blind, crossover study was carried out in 10 healthy volunteers to investigate whether the inclusion of the wetting agent docusate sodium (10 mg) in a combined oral formulation ('Migraleve') with buclizine hydrochloride (6.25 mg), codeine phosphate (8 …
A randomized, double-blind, crossover study was carried out in 10 healthy volunteers to investigate whether the inclusion of the wetting age …
Psyllium is superior to docusate sodium for treatment of chronic constipation.
McRorie JW, Daggy BP, Morel JG, Diersing PS, Miner PB, Robinson M. McRorie JW, et al. Aliment Pharmacol Ther. 1998 May;12(5):491-7. doi: 10.1046/j.1365-2036.1998.00336.x. Aliment Pharmacol Ther. 1998. PMID: 9663731 Free article. Clinical Trial.
The treatment phase compared psyllium (5.1 g b.d.) plus docusate placebo to docusate sodium (100 mg b.d.) plus psyllium placebo. ...RESULTS: Compared to baseline, psyllium increased stool water content vs. docusate (psyllium 2.33% vs. docusate 0.01%, P …
The treatment phase compared psyllium (5.1 g b.d.) plus docusate placebo to docusate sodium (100 mg b.d.) plus psyllium placeb …
Content analysis of bowel protocols for the management of constipation in adult critically ill patients.
Dionne JC, Johnstone J, Smith O, Rose L, Oczkowski S, Arabi Y, Duan EH, Lauzier F, Alhazzani W, Alam N, Zytaruk N, Campisi J, Cook DJ. Dionne JC, et al. J Crit Care. 2020 Aug;58:98-104. doi: 10.1016/j.jcrc.2020.04.006. Epub 2020 Apr 17. J Crit Care. 2020. PMID: 32408108 Clinical Trial.
Less common agents were sodium phosphate (45.9%), glycerin (43.2%), docusate sodium (43.2%), polyethylene glycol 3350 (37.8%), lactulose (29.7%), sodium citrate (16.2%), milk of magnesia (13.5%) and mineral oil (16.2%). ...
Less common agents were sodium phosphate (45.9%), glycerin (43.2%), docusate sodium (43.2%), polyethylene glycol 3350 (37.8%), lactul …
Free fatty acid suppositories are as effective as docusate sodium and sorbitol enemas in treating constipation in children.
Ormarsson OT, Asgrimsdottir GM, Loftsson T, Stefansson E, Lund SH, Bjornsson ES. Ormarsson OT, et al. Acta Paediatr. 2016 Jun;105(6):689-94. doi: 10.1111/apa.13394. Epub 2016 Apr 8. Acta Paediatr. 2016. PMID: 26948070 Clinical Trial.
This phase two clinical trial evaluated the efficacy of suppositories containing free fatty acids (FFA) compared with Klyx docusate sodium and sorbitol enemas. METHODS: A randomised, controlled, single-blind study was undertaken on 77 children aged between one and 17 who p …
This phase two clinical trial evaluated the efficacy of suppositories containing free fatty acids (FFA) compared with Klyx docusate s …
32 results