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2020 3
2021 2
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Efficacy and side-effect profiles of lactulose, docusate sodium, and sennosides compared to PEG in opioid-induced constipation: a systematic review.
Ruston T, Hunter K, Cummings G, Lazarescu A. Ruston T, et al. Can Oncol Nurs J. 2013 Autumn;23(4):236-46. doi: 10.5737/1181912x234236240. Can Oncol Nurs J. 2013. PMID: 24428006 Review. English, French.
Opioid-induced constipation (OIC) is a side effect of opioid therapy that can affect quality of life, adherence to treatment, and morbidity and possibly mortality. OBJECTIVES: To investigate whether docusate sodium, sennosides, and lactulose have equal efficacy and …
Opioid-induced constipation (OIC) is a side effect of opioid therapy that can affect quality of life, adherence to treatment, and morbidity …
Treatments for Constipation: A Review of Systematic Reviews [Internet].
[No authors listed] [No authors listed] Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2014 Nov 17. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2014 Nov 17. PMID: 25535635 Free Books & Documents. Review.
Stool softeners (i.e. docusate sodium or calcium) are thought to facilitate the mixing of aqueous and fatty substances and thereby soften the stool. ...A recent Rapid Review concluded there was a paucity of good quality of evidence to support the use of stool softeners for …
Stool softeners (i.e. docusate sodium or calcium) are thought to facilitate the mixing of aqueous and fatty substances and thereby so …
Randomized, double-blind, placebo-controlled trial of oral docusate in the management of constipation in hospice patients.
Tarumi Y, Wilson MP, Szafran O, Spooner GR. Tarumi Y, et al. J Pain Symptom Manage. 2013 Jan;45(1):2-13. doi: 10.1016/j.jpainsymman.2012.02.008. Epub 2012 Aug 11. J Pain Symptom Manage. 2013. PMID: 22889861 Free article. Clinical Trial.
There is little experimental evidence to support this practice, and no randomized trials have been conducted in the hospice setting. OBJECTIVES: To assess the efficacy of docusate in hospice patients. METHODS: This was a 10-day, prospective, randomized, double-blind, place …
There is little experimental evidence to support this practice, and no randomized trials have been conducted in the hospice setting. OBJECTI …
A comparison of sennosides-based bowel protocols with and without docusate in hospitalized patients with cancer.
Hawley PH, Byeon JJ. Hawley PH, et al. J Palliat Med. 2008 May;11(4):575-81. doi: 10.1089/jpm.2007.0178. J Palliat Med. 2008. PMID: 18454610
The docusate-containing protocol had an initial docusate-only step for patients not taking opioids, and four to six 100-mg capsules of docusate sodium in addition to the sennosides for the rest of the protocol. METHODS: Thirty patients received the …
The docusate-containing protocol had an initial docusate-only step for patients not taking opioids, and four to six 100-mg cap …
Palatability of Crushed Over-the-Counter Medications.
Lovell AG, Protus BM, Dickman JR, Saphire ML. Lovell AG, et al. J Pain Symptom Manage. 2021 Apr;61(4):755-762. doi: 10.1016/j.jpainsymman.2020.09.020. Epub 2020 Sep 22. J Pain Symptom Manage. 2021. PMID: 32976943
Eight OTC medications were crushed and mixed in applesauce: naproxen, fexofenadine, phenazopyridine, multivitamin, loperamide, famotidine, sennosides, and sennosides-docusate. Participants were blinded to medication samples and control (plain applesauce). ... …
Eight OTC medications were crushed and mixed in applesauce: naproxen, fexofenadine, phenazopyridine, multivitamin, loperamide, famotidine, …
Dioctyl Sulfosuccinate or Docusate (Calcium or Sodium) for the Prevention or Management of Constipation: A Review of the Clinical Effectiveness.
[No authors listed] [No authors listed] Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2014 Jun 26. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2014 Jun 26. PMID: 25520993 Free Books & Documents. Review.
Current treatment options include dietary or bulking agents (i.e. psyllium seed husk), osmotic laxatives (i.e. lactulose, sorbitol, polyethylene glycol [PEG]), stimulant laxatives (i.e. sennosides, bisacodyl, sodium picosulfate), and stool softeners (i.e. docusate s …
Current treatment options include dietary or bulking agents (i.e. psyllium seed husk), osmotic laxatives (i.e. lactulose, sorbitol, polyethy …
The Role of Docusate for Constipation in Older People.
Nguyen T. Nguyen T. Sr Care Pharm. 2021 Oct 1;36(10):501-507. doi: 10.4140/TCP.n.2021.501. Sr Care Pharm. 2021. PMID: 34593092
Data Synthesis: Docusate when compared with placebo or psyllium or sennosides in these trials did not show any benefits for constipation. Psyllium and sennosides showed to be more effective compared with docusate. No differences found between docusa
Data Synthesis: Docusate when compared with placebo or psyllium or sennosides in these trials did not show any benefits for co …
Update in hospital palliative care.
Anderson WG, Flint LA, Horton JR, Johnson K, Mourad M, Sharpe BA. Anderson WG, et al. J Hosp Med. 2013 Dec;8(12):715-20. doi: 10.1002/jhm.2110. Epub 2013 Nov 8. J Hosp Med. 2013. PMID: 24214838 Free PMC article. Review.
RESULTS: Key findings include: indwelling pleural catheters and talc pleurodesis provide similar relief of dyspnea in patients with malignant pleural effusions; oxygen many not be needed to prevent dyspnea in many dying patients; docusate may not be needed in addition to …
RESULTS: Key findings include: indwelling pleural catheters and talc pleurodesis provide similar relief of dyspnea in patients with malignan …
Effect of an electronic medical record design modification on laxative co-prescribing among hospitalised patients taking opioids: A before-and-after study.
Liu S, Gnjidic D, Patanwala AE, Rubin G, Nielsen M, Penm J. Liu S, et al. Int J Med Inform. 2020 Aug;140:104172. doi: 10.1016/j.ijmedinf.2020.104172. Epub 2020 May 15. Int J Med Inform. 2020. PMID: 32473568
METHODS: In this retrospective 3-month before-and-after study, an EMR modification to improve docusate with sennosides order sentence visibility was implemented on 21 February 2018, at a teaching hospital in Sydney, Australia. The primary outcome was the co-prescrip …
METHODS: In this retrospective 3-month before-and-after study, an EMR modification to improve docusate with sennosides order s …
16 results