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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1993 4
1994 3
1995 3
1996 10
1997 34
1998 94
1999 91
2000 103
2001 97
2002 132
2003 173
2004 209
2005 180
2006 216
2007 187
2008 206
2009 182
2010 199
2011 192
2012 225
2013 233
2014 214
2015 255
2016 245
2017 259
2018 283
2019 269
2020 319
2021 317
2022 330
2023 77
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4,831 results
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Page 1
Efficacy of acetylcholinesterase inhibitors in Alzheimer's disease.
Marucci G, Buccioni M, Ben DD, Lambertucci C, Volpini R, Amenta F. Marucci G, et al. Neuropharmacology. 2021 Jun 1;190:108352. doi: 10.1016/j.neuropharm.2020.108352. Epub 2020 Oct 6. Neuropharmacology. 2021. PMID: 33035532 Free article. Review.
Alzheimer's disease (AD), the most common cause of adult-onset dementia is characterized by a progressive decline of cognitive functions accompanied by behavioral manifestations. ...The first ChE-I licensed for symptomatic treatment of AD was tacrine. The ChE-Is currently …
Alzheimer's disease (AD), the most common cause of adult-onset dementia is characterized by a progressive decline of cognitive functi …
Clinical efficacy and safety of donepezil in the treatment of Alzheimer's disease in Chinese patients.
Zhang N, Gordon ML. Zhang N, et al. Clin Interv Aging. 2018 Oct 11;13:1963-1970. doi: 10.2147/CIA.S159920. eCollection 2018. Clin Interv Aging. 2018. PMID: 30349215 Free PMC article. Review.
Donepezil, an acetylcholinesterase inhibitor (AChEI), has been widely used to treat Alzheimer's disease (AD) in China. ...We include Chinese clinical trials and other well-designed studies investigating donepezil or using donepezil as a positive contro …
Donepezil, an acetylcholinesterase inhibitor (AChEI), has been widely used to treat Alzheimer's disease (AD) in China. ...We i …
Memantine, Donepezil, or Combination Therapy-What is the best therapy for Alzheimer's Disease? A Network Meta-Analysis.
Guo J, Wang Z, Liu R, Huang Y, Zhang N, Zhang R. Guo J, et al. Brain Behav. 2020 Nov;10(11):e01831. doi: 10.1002/brb3.1831. Epub 2020 Sep 10. Brain Behav. 2020. PMID: 32914577 Free PMC article.
INTRODUCTION: Alzheimer's disease (AD) is a degenerative brain disease that progresses over time, heavily burdening patients, families, and aging societies worldwide. Memantine and donepezil are frequently used in its treatment, both as monotherapy and in combinatio …
INTRODUCTION: Alzheimer's disease (AD) is a degenerative brain disease that progresses over time, heavily burdening patients, familie …
Donepezil for dementia due to Alzheimer's disease.
Govind N. Govind N. Br J Community Nurs. 2020 Mar 2;25(3):148-149. doi: 10.12968/bjcn.2020.25.3.148. Br J Community Nurs. 2020. PMID: 32160022 Review. No abstract available.
The Efficacy and Safety of Alzheimer's Disease Therapies: An Updated Umbrella Review.
Fan F, Liu H, Shi X, Ai Y, Liu Q, Cheng Y. Fan F, et al. J Alzheimers Dis. 2022;85(3):1195-1204. doi: 10.3233/JAD-215423. J Alzheimers Dis. 2022. PMID: 34924395
BACKGROUND: Evidence summaries for efficacy and safety of frequently employed treatments of Alzheimer's disease (AD) are sparse. OBJECTIVE: We aimed to perform an updated umbrella review to identify an efficacious and safe treatment for AD patients. ...RESULTS: Sixteen eli …
BACKGROUND: Evidence summaries for efficacy and safety of frequently employed treatments of Alzheimer's disease (AD) are sparse. OBJE …
The treatment of cognitive dysfunction in dementia: a multiple treatments meta-analysis.
Perng CH, Chang YC, Tzang RF. Perng CH, et al. Psychopharmacology (Berl). 2018 May;235(5):1571-1580. doi: 10.1007/s00213-018-4867-y. Epub 2018 Mar 3. Psychopharmacology (Berl). 2018. PMID: 29502274

The results of meta-regression showed that in young patients (beta = - 0.036, p value < 0.001) with vascular dementia (beta = 0.603, p value < 0.001), the efficacies of treatment 2 (symptomatic treatment for vascular dementia with piracetam, nimodipine, aniracetam, flunariz

…

The results of meta-regression showed that in young patients (beta = - 0.036, p value < 0.001) with vascular dementia (beta = 0.603, p va

…
Donepezil in the treatment of ischemic stroke: Review and future perspective.
Barfejani AH, Jafarvand M, Seyedsaadat SM, Rasekhi RT. Barfejani AH, et al. Life Sci. 2020 Dec 15;263:118575. doi: 10.1016/j.lfs.2020.118575. Epub 2020 Oct 12. Life Sci. 2020. PMID: 33058916 Review.
As such, adjunct therapies that can protect neurons during acute ischemic phase prior to revascularization have the potential of enhancing functional recovery. Donepezil, an acetylcholinesterase inhibitor, improves cognition and global function in patients with Alzheimer' …
As such, adjunct therapies that can protect neurons during acute ischemic phase prior to revascularization have the potential of enhancing f …
Efficacy and safety of donepezil for mild cognitive impairment: A systematic review and meta-analysis.
Zhang X, Lian S, Zhang Y, Zhao Q. Zhang X, et al. Clin Neurol Neurosurg. 2022 Feb;213:107134. doi: 10.1016/j.clineuro.2022.107134. Epub 2022 Jan 19. Clin Neurol Neurosurg. 2022. PMID: 35078087 Review.
OBJECTIVE: This study intends to systematically evaluate the efficacy and safety of donepezil for improving cognitive function in patients with mild cognitive impairment (MCI), and to provide evidence-based foundation for donepezil in MCI treatment. ...CONCLUSION: …
OBJECTIVE: This study intends to systematically evaluate the efficacy and safety of donepezil for improving cognitive function in pat …
Comparative safety and efficacy of cognitive enhancers for Alzheimer's dementia: a systematic review with individual patient data network meta-analysis.
Veroniki AA, Ashoor HM, Rios P, Seitidis G, Stewart L, Clarke M, Tudur-Smith C, Mavridis D, Hemmelgarn BR, Holroyd-Leduc J, Straus SE, Tricco AC. Veroniki AA, et al. BMJ Open. 2022 Apr 26;12(4):e053012. doi: 10.1136/bmjopen-2021-053012. BMJ Open. 2022. PMID: 35473731 Free PMC article.
RESULTS: Our IPD-NMA compared nine treatments (including placebo). Donepezil (mean difference (MD)=1.41, 95% CI: 0.51 to 2.32) and donepezil +memantine (MD=2.57, 95% CI: 0.07 to 5.07) improved MMSE score (56 RCTs, 11 619 participants; CINeMA score: moderate) compare …
RESULTS: Our IPD-NMA compared nine treatments (including placebo). Donepezil (mean difference (MD)=1.41, 95% CI: 0.51 to 2.32) and …
Donepezil ameliorates oxaliplatin-induced peripheral neuropathy via a neuroprotective effect.
Kawashiri T, Shimizu S, Shigematsu N, Kobayashi D, Shimazoe T. Kawashiri T, et al. J Pharmacol Sci. 2019 Jul;140(3):291-294. doi: 10.1016/j.jphs.2019.05.009. Epub 2019 Jul 19. J Pharmacol Sci. 2019. PMID: 31377017 Free article.
Oxaliplatin induces severe peripheral neuropathy. The effect of donepezil, a drug used for treatment of Alzheimer's disease, on oxaliplatin-induced peripheral neuropathy was investigated using both in vivo and in vitro models. ...Therefore, donepezil may be u …
Oxaliplatin induces severe peripheral neuropathy. The effect of donepezil, a drug used for treatment of Alzheimer's disease, o …
4,831 results