Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1968 2
1969 12
1970 12
1971 9
1972 15
1973 5
1974 10
1975 7
1976 5
1977 5
1978 7
1979 2
1980 6
1981 7
1982 11
1983 8
1984 9
1985 11
1986 12
1987 1
1988 6
1989 5
1990 2
1991 3
1992 2
1993 4
1994 7
1995 7
1996 6
1997 8
1998 3
1999 4
2000 3
2001 5
2002 5
2003 4
2004 6
2005 1
2006 1
2007 8
2008 4
2009 1
2010 3
2011 5
2012 2
2013 3
2014 3
2015 3
2016 2
2017 2
2019 3
2020 3
2021 1
2022 1
2023 2
2024 1
2025 1
2026 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

280 results

Results by year

Filters applied: . Clear all
Page 1
Comparison of gabapentin and doxepin in the management of uremic pruritus: A randomized crossover clinical trial.
Haber R, Bachour J, Salloum A, Maacaron T, Khoury F, Habr L, Ammoury A, Joubran N. Haber R, et al. Dermatol Ther. 2020 Nov;33(6):e14522. doi: 10.1111/dth.14522. Epub 2020 Nov 23. Dermatol Ther. 2020. PMID: 33176043 Clinical Trial.
Gabapentin and doxepin are well-known treatments of uremic pruritus in hemodialysis patients but no head-to-head studies were conducted to date. ...VAS scores at baseline were 6.71 and 6.14, and dropped to 0.57 and 2.35 at week 4 in the gabapentin and doxepin groups …
Gabapentin and doxepin are well-known treatments of uremic pruritus in hemodialysis patients but no head-to-head studies were conduct …
A novel chitosan-based doxepin nano-formulation for chemotherapy-induced oral mucositis: a randomized, double-blinded, placebo-controlled clinical trial.
Samiraninezhad N, Rezaee M, Gholami A, Amanati A, Mardani M. Samiraninezhad N, et al. Inflammopharmacology. 2023 Oct;31(5):2411-2420. doi: 10.1007/s10787-023-01325-7. Epub 2023 Sep 5. Inflammopharmacology. 2023. PMID: 37668810 Clinical Trial.
OBJECTIVES: Considering the prevalence of oral mucositis, we aimed to use the analgesic effects of doxepin with chitosan's antimicrobial and bio-adhesive nature to fabricate a nano-formulation for treating chemotherapy-induced oral mucositis. ...Sixty patients were randoml …
OBJECTIVES: Considering the prevalence of oral mucositis, we aimed to use the analgesic effects of doxepin with chitosan's antimicrob …
Clinical efficacy and safety of low-dose doxepin in Chinese patients with generalized anxiety disorder: A before-after study.
Zhang M, Huang F, Jiang F, Mai M, Guo X, Zhang Y, Xu Y, Zu H. Zhang M, et al. Medicine (Baltimore). 2022 Oct 21;101(42):e31201. doi: 10.1097/MD.0000000000031201. Medicine (Baltimore). 2022. PMID: 36281170 Free PMC article. Clinical Trial.
Clinical and animal studies have reported that low-dose doxepin may have positive effects on generalized anxiety disorder (GAD); however, its effectiveness and clinical safety are less well understood. ...Bodyweight (62.00 7.45 vs 64.00 6.44 kg, P = .23) and BMI (23.70 …
Clinical and animal studies have reported that low-dose doxepin may have positive effects on generalized anxiety disorder (GAD); howe …
Doxepin hydrochloride.
Hollister LE. Hollister LE. Ann Intern Med. 1974 Sep;81(3):360-3. doi: 10.7326/0003-4819-81-3-360. Ann Intern Med. 1974. PMID: 4604347 Clinical Trial. No abstract available.
Self-evaluations of antidepressants.
McNair DM. McNair DM. Psychopharmacologia. 1974;37(4):281-302. doi: 10.1007/BF00428915. Psychopharmacologia. 1974. PMID: 4153054 Review. No abstract available.
The effect of doxepin 3 mg on sleep latency: a pooled analysis of two phase 3 trials.
Fisher M, Araga M, Franks B, Krystal A. Fisher M, et al. Sleep Breath. 2025 Apr 14;29(2):158. doi: 10.1007/s11325-025-03328-w. Sleep Breath. 2025. PMID: 40229607 Free PMC article. Clinical Trial.
This analysis assessed the utility of doxepin 3 mg in the treatment of difficulties with sleep onset. PATIENTS AND METHODS: A pooled analysis of two phase 3, randomized, controlled trials was conducted. ...RESULTS: A total of 310 patients, 153 randomized to placebo and 157 …
This analysis assessed the utility of doxepin 3 mg in the treatment of difficulties with sleep onset. PATIENTS AND METHODS: A pooled …
A randomized controlled clinical trial comparing "guideline exposed" and "guideline naive" physicians in respect to dosage selection and treatment outcome with doxepin in depressive disorders.
Linden M, Schotte K. Linden M, et al. Pharmacopsychiatry. 2007 Mar;40(2):77-81. doi: 10.1055/s-2007-972574. Pharmacopsychiatry. 2007. PMID: 17447178 Clinical Trial.
METHODS: 161 general practitioners and 162 psychiatrists in private practice documented 1319 patients, receiving doxepin for individual clinical reasons. Physicians were randomly divided into a guideline exposed and a control group. ...
METHODS: 161 general practitioners and 162 psychiatrists in private practice documented 1319 patients, receiving doxepin for individu …
Doxepin is more effective than zolpidem in improving executive function in patients with insomnia disorder.
Yu Z, Han L, Yan P, Liu W, Ren L, Xu Y, Yang L, Ma L, Liu Y, Wang S. Yu Z, et al. Sleep Breath. 2024 May;28(2):929-934. doi: 10.1007/s11325-023-02972-4. Epub 2023 Dec 20. Sleep Breath. 2024. PMID: 38123719 Clinical Trial.
BACKGROUND : Insomnia disorder is associated with an impairment in cognitive performance. Doxepin and zolpidem have been found to be effective in improving sleep. In this study, we aimed to compare the effects of doxepin and zolpidem on sleep structure and executive …
BACKGROUND : Insomnia disorder is associated with an impairment in cognitive performance. Doxepin and zolpidem have been found to be …
Doxepin inhibits CYP2D6 activity in vivo.
Szewczuk-Bogusławska M, Kiejna A, Beszłej JA, Orzechowska-Juzwenko K, Milejski P. Szewczuk-Bogusławska M, et al. Pol J Pharmacol. 2004 Jul-Aug;56(4):491-4. Pol J Pharmacol. 2004. PMID: 15520506 Free article. Clinical Trial.
OBJECTIVE: Doxepin is a tricyclic antidepressant formulated as a mixture of E-(trans) and Z-(cis) stereoisomers. Cytochrome P450 2D6 (CYP2D6) catalyzes the hydroxylation of E-doxepin and E-N-desmethyldoxepin stereospecically. There is evidence that tricyclic antidep …
OBJECTIVE: Doxepin is a tricyclic antidepressant formulated as a mixture of E-(trans) and Z-(cis) stereoisomers. Cytochrome P450 2D6 …
Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial.
Sio TT, Le-Rademacher JG, Leenstra JL, Loprinzi CL, Rine G, Curtis A, Singh AK, Martenson JA Jr, Novotny PJ, Tan AD, Qin R, Ko SJ, Reiter PL, Miller RC. Sio TT, et al. JAMA. 2019 Apr 16;321(15):1481-1490. doi: 10.1001/jama.2019.3504. JAMA. 2019. PMID: 30990550 Free PMC article. Clinical Trial.
OBJECTIVE: To evaluate the effect of doxepin mouthwash or diphenhydramine-lidocaine-antacid mouthwash for the treatment of oral mucositis-related pain. ...Fatigue was reported by 5 patients (6%) in the doxepin mouthwash group and no patients in the diphenhydramine-l …
OBJECTIVE: To evaluate the effect of doxepin mouthwash or diphenhydramine-lidocaine-antacid mouthwash for the treatment of oral mucos …
280 results