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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1968 6
1969 5
1970 4
1971 5
1972 13
1973 8
1974 15
1975 20
1976 16
1977 4
1978 12
1979 9
1980 22
1981 11
1982 14
1983 15
1984 13
1985 12
1986 12
1987 24
1988 26
1989 27
1990 32
1991 22
1992 26
1993 25
1994 26
1995 21
1996 17
1997 20
1998 21
1999 20
2000 24
2001 25
2002 27
2003 32
2004 35
2005 41
2006 46
2007 39
2008 54
2009 34
2010 42
2011 35
2012 52
2013 40
2014 34
2015 38
2016 29
2017 26
2018 28
2019 22
2020 19
2021 34
2022 21
2023 31
2024 25
2025 29
2026 27

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1,304 results

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Page 1
Doxycycline Prophylaxis to Prevent Sexually Transmitted Infections in Women.
Stewart J, Oware K, Donnell D, Violette LR, Odoyo J, Soge OO, Scoville CW, Omollo V, Mogaka FO, Sesay FA, McClelland RS, Spinelli M, Gandhi M, Bukusi EA, Baeten JM; dPEP Kenya Study Team. Stewart J, et al. N Engl J Med. 2023 Dec 21;389(25):2331-2340. doi: 10.1056/NEJMoa2304007. N Engl J Med. 2023. PMID: 38118022 Free PMC article. Clinical Trial.
METHODS: We conducted a randomized, open-label trial comparing doxycycline PEP (doxycycline hyclate, 200 mg taken within 72 hours after condomless sex) with standard care among Kenyan women 18 to 30 years of age who were receiving preexposure prophylaxis agai …
METHODS: We conducted a randomized, open-label trial comparing doxycycline PEP (doxycycline hyclate, 200 mg taken withi …
Efficacy of Spironolactone Compared with Doxycycline in Moderate Acne in Adult Females: Results of the Multicentre, Controlled, Randomized, Double-blind Prospective and Parallel Female Acne Spironolactone vs doxyCycline Efficacy (FASCE) Study.
Dréno B, Nguyen JM, Hainaut E, Machet L, Leccia MT, Beneton N, Claudel JP, Célérier P, Le Moigne M, Le Naour S, Vrignaud F, Poinas A, Dert C, Boisrobert A, Flet L, Korner S, Khammari A. Dréno B, et al. Acta Derm Venereol. 2024 Feb 21;104:adv26002. doi: 10.2340/actadv.v104.26002. Acta Derm Venereol. 2024. PMID: 38380975 Free PMC article. Clinical Trial.
Spironolactone performed better at month 4 and showed a statistically significant better treatment success after 6 months than doxycycline (p = 0.007). Spironolactone was 1.37-times and 2.87-times more successful compared with doxycycline at respective time-points. …
Spironolactone performed better at month 4 and showed a statistically significant better treatment success after 6 months than doxycyclin …
A Randomized Controlled Trial of Ceftriaxone and Doxycycline, With or Without Metronidazole, for the Treatment of Acute Pelvic Inflammatory Disease.
Wiesenfeld HC, Meyn LA, Darville T, Macio IS, Hillier SL. Wiesenfeld HC, et al. Clin Infect Dis. 2021 Apr 8;72(7):1181-1189. doi: 10.1093/cid/ciaa101. Clin Infect Dis. 2021. PMID: 32052831 Free PMC article. Clinical Trial.
CONCLUSIONS: In women treated for acute PID, the addition of metronidazole to ceftriaxone and doxycycline was well tolerated and resulted in reduced endometrial anaerobes, decreased M. genitalium, and reduced pelvic tenderness compared to ceftriaxone and doxycycline …
CONCLUSIONS: In women treated for acute PID, the addition of metronidazole to ceftriaxone and doxycycline was well tolerated and resu …
Impact of doxycycline post-exposure prophylaxis for sexually transmitted infections on the gut microbiome and antimicrobial resistome.
Chu VT, Glascock A, Donnell D, Grabow C, Brown CE, Ward R, Love C, Kalantar KL, Cohen SE, Cannon C, Woodworth MH, Kelley CF, Celum C, Luetkemeyer AF, Langelier CR. Chu VT, et al. Nat Med. 2025 Jan;31(1):207-217. doi: 10.1038/s41591-024-03274-2. Epub 2024 Oct 3. Nat Med. 2025. PMID: 39363100 Free PMC article. Clinical Trial.
Doxycycline post-exposure prophylaxis (doxy-PEP) reduces bacterial sexually transmitted infections among men who have sex with men and transgender women. ...As doxy-PEP is implemented as a public health strategy, further studies and population-level surveillance of doxy …
Doxycycline post-exposure prophylaxis (doxy-PEP) reduces bacterial sexually transmitted infections among men who have sex with men an …
Comparative evaluation of demineralized freeze-dried bone allograft with and without doxycycline hyclate loaded proniosomal gel in the treatment of class II furcation defects: a randomized controlled trial.
Biradar V, Mody D, Kolte AP, Lathiya V. Biradar V, et al. Clin Oral Investig. 2025 Oct 20;29(11):520. doi: 10.1007/s00784-025-06570-4. Clin Oral Investig. 2025. PMID: 41114850 Clinical Trial.
The study aimed to assess and compare the clinical and radiographic outcomes of using demineralized freeze-dried bone allograft (DFDBA) alone versus its combination with doxycycline hyclate loaded proniosomal gel in the management of Class II Furcation defects. ...F …
The study aimed to assess and compare the clinical and radiographic outcomes of using demineralized freeze-dried bone allograft (DFDBA) alon …
Comparative pharmacokinetics of a new oral long-acting formulation of doxycycline hyclate: A canine clinical trial.
Arciniegas Ruiz SM, Gutiérrez Olvera L, Bernad Bernad MJ, Caballero Chacón Sdel C, Vargas Estrada D. Arciniegas Ruiz SM, et al. Eur J Pharm Sci. 2015 Dec 1;80:9-15. doi: 10.1016/j.ejps.2015.09.012. Epub 2015 Sep 21. Eur J Pharm Sci. 2015. PMID: 26393684 Clinical Trial.
The aim of this study was to determine the pharmacokinetics of four formulations of doxycycline hyclate, administered orally, with different proportions of excipients, acrylic acid-polymethacrylate-based matrices, to obtain longer therapeutic levels than conventiona …
The aim of this study was to determine the pharmacokinetics of four formulations of doxycycline hyclate, administered orally, …
A randomized, double-blind, placebo-controlled trial of the combined effect of doxycycline hyclate 20-mg tablets and metronidazole 0.75% topical lotion in the treatment of rosacea.
Sanchez J, Somolinos AL, Almodóvar PI, Webster G, Bradshaw M, Powala C. Sanchez J, et al. J Am Acad Dermatol. 2005 Nov;53(5):791-7. doi: 10.1016/j.jaad.2005.04.069. Epub 2005 Sep 15. J Am Acad Dermatol. 2005. PMID: 16243127 Clinical Trial.
BACKGROUND: Subantimicrobial doses of doxycycline may improve outcomes in rosacea when combined with topical metronidazole and used as maintenance monotherapy. OBJECTIVE: The purpose of this study was to evaluate the safety and efficacy of doxycycline hyclate …
BACKGROUND: Subantimicrobial doses of doxycycline may improve outcomes in rosacea when combined with topical metronidazole and used a …
Clinical and microbiological effects of a subantimicrobial dose of oral doxycycline on periodontitis in dogs.
Kim SE, Hwang SY, Jeong M, Lee Y, Lee ER, Park YW, Ahn JS, Kim S, Seo K. Kim SE, et al. Vet J. 2016 Feb;208:55-9. doi: 10.1016/j.tvjl.2015.10.006. Epub 2015 Oct 13. Vet J. 2016. PMID: 26639830 Clinical Trial.
Using the agar dilution method, the minimum bactericidal concentration of doxycycline was evaluated and the resistance for doxycycline was monitored during this experimental phase. ...These results suggest that the once daily oral regimen of 2 mg/kg of doxycyclin …
Using the agar dilution method, the minimum bactericidal concentration of doxycycline was evaluated and the resistance for doxycyc …
Double-blind placebo-controlled randomized clinical trial evaluating doxycycline effects on chemotherapy-induced oral mucositis.
Ramírez-Amador V, Anaya-Saavedra G, Labardini-Méndez J, Ponce de León-Rosales S. Ramírez-Amador V, et al. J Clin Pharm Ther. 2018 Apr;43(2):202-208. doi: 10.1111/jcpt.12633. Epub 2017 Sep 25. J Clin Pharm Ther. 2018. PMID: 28948645 Clinical Trial.
Individuals were stratified by leukaemia type and assigned randomly to receive doxycycline hyclate (50 mg/d) (doxycycline group: DG) or placebo (placebo group: PG) before and during CT. ...WHAT IS NEW AND CONCLUSION: Subantimicrobial doses of doxycycline …
Individuals were stratified by leukaemia type and assigned randomly to receive doxycycline hyclate (50 mg/d) (doxycycline …
Trichomonas vaginalis Among Cisgender Women Taking Doxycycline Postexposure Prophylaxis.
Sesay FA, Oware K, Violette LR, Donnell D, Odoyo JB, Omollo V, Mogaka FO, McClelland RS, Balkus JE, Bukusi EA, Baeten JM, Stewart J. Sesay FA, et al. J Infect Dis. 2026 Feb 18;233(2):411-415. doi: 10.1093/infdis/jiaf519. J Infect Dis. 2026. PMID: 41063661 Free PMC article. Clinical Trial.
Doxycycline treats and prevents several bacterial and parasitic infections and has been proposed as a possible treatment for Trichomonas vaginalis. ...Among 224 cisgender women randomized to doxycycline postexposure prophylaxis and 225 to standard-of-care, there wer …
Doxycycline treats and prevents several bacterial and parasitic infections and has been proposed as a possible treatment for Trichomo …
1,304 results