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181 results

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Page 1
The effects of combination therapy with dutasteride and tamsulosin on clinical outcomes in men with symptomatic benign prostatic hyperplasia: 4-year results from the CombAT study.
Roehrborn CG, Siami P, Barkin J, Damião R, Major-Walker K, Nandy I, Morrill BB, Gagnier RP, Montorsi F; CombAT Study Group. Roehrborn CG, et al. Eur Urol. 2010 Jan;57(1):123-31. doi: 10.1016/j.eururo.2009.09.035. Epub 2009 Sep 19. Eur Urol. 2010. PMID: 19825505 Clinical Trial.
INTERVENTION: Oral daily tamsulosin, 0.4 mg; dutasteride, 0.5 mg; or a combination of both. MEASUREMENTS: The 4-yr primary end point was time to first AUR or BPH-related surgery. ...RESULTS AND LIMITATIONS: Combination therapy was significantly superior to tamsul …
INTERVENTION: Oral daily tamsulosin, 0.4 mg; dutasteride, 0.5 mg; or a combination of both. MEASUREMENTS: The 4-yr primary end …
Dutasteride.
Evans HC, Goa KL. Evans HC, et al. Drugs Aging. 2003;20(12):905-16; discussion 917-8. doi: 10.2165/00002512-200320120-00005. Drugs Aging. 2003. PMID: 14565784 Review.
Dutasteride, a potent inhibitor of type 1 and 2 5alpha-reductase, reduced dihydrotestosterone levels by >90% in 85% of patients following 1 years' administration of oral dutasteride 0.5 mg/day. ...A nonblind extension study found that dutasteride maintains …
Dutasteride, a potent inhibitor of type 1 and 2 5alpha-reductase, reduced dihydrotestosterone levels by >90% in 85% of patients fo …
Effects of dutasteride and tamsulosin on penile morphology in a rodent model.
da Silva MHA, Costa WS, Sampaio FJB, de Souza DB. da Silva MHA, et al. Int Braz J Urol. 2023 May-Jun;49(3):320-333. doi: 10.1590/S1677-5538.IBJU.2022.0583. Int Braz J Urol. 2023. PMID: 37115177 Free PMC article.
PURPOSE: To evaluate the penile morphology after the isolated and combined administration of dutasteride and tamsulosin in a rodent model. MATERIALS AND METHODS: Forty male rats were assigned into the following groups: Control group (C, receiving distilled water, n= …
PURPOSE: To evaluate the penile morphology after the isolated and combined administration of dutasteride and tamsulosin in a r …
Tamsulosin and Dutasteride Combination Therapy for Asian Men With Moderate-to-Severe Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia: A Systematic Review of Clinical Considerations That Influence the Prescription.
Yang F, Hashim R, Philippou J. Yang F, et al. J Clin Med Res. 2024 Sep;16(9):385-397. doi: 10.14740/jocmr5255. Epub 2024 Sep 12. J Clin Med Res. 2024. PMID: 39346571 Free PMC article. Review.
This systematic review aimed to identify the clinical considerations that influence the decision to prescribe combination therapy of tamsulosin 0.4 mg + dutasteride 0.5 mg for Asian men with LUTS/BPH. This review followed the Preferred Reporting Items for Systematic …
This systematic review aimed to identify the clinical considerations that influence the decision to prescribe combination therapy of tams …
Efficacy and Safety of Combination Tamsulosin and Dutasteride versus Tamsulosin Monotherapy for Benign Prostatic Hyperplasia: A Meta-Analysis.
Yu H, Chen H, Wang X, Li J, Shen X, Ye X. Yu H, et al. Arch Esp Urol. 2025 Aug;78(7):866-876. doi: 10.56434/j.arch.esp.urol.20257807.115. Arch Esp Urol. 2025. PMID: 40922439 Free article.
BACKGROUND: We conducted a meta-analysis to compare the efficacy and drug-related adverse events (AEs) of the combination of tamsulosin and dutasteride versus tamsulosin monotherapy for the treatment of benign prostatic hyperplasia (BPH). ...CONCLUSIONS: In p …
BACKGROUND: We conducted a meta-analysis to compare the efficacy and drug-related adverse events (AEs) of the combination of tamsulosin …
Fixed-dose combination therapy with dutasteride and tamsulosin in the management of benign prostatic hyperplasia.
Dimitropoulos K, Gravas S. Dimitropoulos K, et al. Ther Adv Urol. 2016 Feb;8(1):19-28. doi: 10.1177/1756287215607419. Ther Adv Urol. 2016. PMID: 26834837 Free PMC article. Review.
Following previous studies on the separate administration of dutasteride and tamsulosin, a fixed-dose combination capsule of tamsulosin 0.4 mg and dutasteride 0.5 mg has been approved and released for clinical use in men with BPH. The present review ai …
Following previous studies on the separate administration of dutasteride and tamsulosin, a fixed-dose combination capsule of …
The Effect of Tamsulosin, Dutasteride Monotherapy and Tamsulosin-Dutasteride Combination on Prostate Smooth Muscle Contractility in BPH Model Wistar Strain Rattus Novergicus.
Daryanto B, Naim HY, Budaya TN. Daryanto B, et al. Med Arch. 2023 Feb;77(1):13-17. doi: 10.5455/medarh.2023.77.13-17. Med Arch. 2023. PMID: 36919125 Free PMC article.
OBJECTIVE: Our study aimed to determine the effect of long-term administration of tamsulosin, dutasteride and tamsulosin-dutasteride combination on the contractility of prostate smooth muscle cells in BPH model rats. ...In addition, there was a differe …
OBJECTIVE: Our study aimed to determine the effect of long-term administration of tamsulosin, dutasteride and tamsulosin …
Combined medical treatment using dutasteride and tamsulosin for lower urinary tract symptoms suggestive of benign prostatic hyperplasia.
Djavan B, Handl MJ, Dianat S. Djavan B, et al. Expert Opin Pharmacother. 2010 Oct;11(15):2535-47. doi: 10.1517/14656566.2010.516901. Expert Opin Pharmacother. 2010. PMID: 20854184 Review.
Safety and efficacy of combination therapy with dutasteride and tamsulosin as well as long-term benefit on prevention of disease progression have been widely studied in recent trials. AREAS COVERED IN THIS REVIEW: The present article summarizes the pharmacologic pro …
Safety and efficacy of combination therapy with dutasteride and tamsulosin as well as long-term benefit on prevention of disea …
Dutasteride/tamsulosin: in benign prostatic hyperplasia.
Keating GM. Keating GM. Drugs Aging. 2012 May 1;29(5):405-19. doi: 10.2165/11208920-000000000-00000. Drugs Aging. 2012. PMID: 22550968 Review.
The mean change from baseline in the total International Prostate Symptom Score was significantly greater with dutasteride plus tamsulosin than with dutasteride or tamsulosin alone after 2 years (primary endpoint) and 4 years of therapy. ...In the Comb …
The mean change from baseline in the total International Prostate Symptom Score was significantly greater with dutasteride plus ta …
Combination therapy with dutasteride and tamsulosin for the treatment of symptomatic enlarged prostate.
Miller J, Tarter TH. Miller J, et al. Clin Interv Aging. 2009;4:251-8. doi: 10.2147/cia.s4102. Epub 2009 Jun 9. Clin Interv Aging. 2009. PMID: 19554096 Free PMC article. Review.
Interim results of the ongoing Combination of Avodart and Tamsulosin (CombAt) study have shown combination therapy with the 5alpha-reductase inhibitor dutasteride and the alpha1-adrenergic antagonist tamsulosin offer significant improvements from baseline com …
Interim results of the ongoing Combination of Avodart and Tamsulosin (CombAt) study have shown combination therapy with the 5alpha-re …
181 results