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2003 1
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2010 8
2011 7
2012 5
2013 1
2014 4
2015 4
2016 2
2017 1
2019 1
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Page 1
Effects of eszopiclone on sleep quality and cognitive function in elderly patients with Alzheimer's disease and sleep disorder: A randomized controlled trial.
Huo S, Cheng L, Li S, Xu F. Huo S, et al. Brain Behav. 2022 Feb;12(2):e2488. doi: 10.1002/brb3.2488. Epub 2022 Jan 18. Brain Behav. 2022. PMID: 35041261 Free PMC article. Clinical Trial.
OBJECTIVE: To investigate the effects of eszopiclone on sleep quality and cognitive function in elderly patients with Alzheimer's disease (AD) and sleep disorders. ...After treatment, the scores of the physical life self-care scale and instrumental activities of daily livi …
OBJECTIVE: To investigate the effects of eszopiclone on sleep quality and cognitive function in elderly patients with Alzheimer's dis …
The effects of eszopiclone on sleep spindles and memory consolidation in schizophrenia: a randomized clinical trial.
Mylonas D, Baran B, Demanuele C, Cox R, Vuper TC, Seicol BJ, Fowler RA, Correll D, Parr E, Callahan CE, Morgan A, Henderson D, Vangel M, Stickgold R, Manoach DS. Mylonas D, et al. Neuropsychopharmacology. 2020 Dec;45(13):2189-2197. doi: 10.1038/s41386-020-00833-2. Epub 2020 Sep 12. Neuropsychopharmacology. 2020. PMID: 32919407 Free PMC article. Clinical Trial.
This larger double-blind crossover study that included healthy controls investigated whether eszopiclone could both increase N2 spindle density and improve memory. ...Patients showed a widespread reduction of spindle density and, in both groups, eszopiclone increase …
This larger double-blind crossover study that included healthy controls investigated whether eszopiclone could both increase N2 spind …
Eszopiclone improves overnight polysomnography and continuous positive airway pressure titration: a prospective, randomized, placebo-controlled trial.
Lettieri CJ, Quast TN, Eliasson AH, Andrada T. Lettieri CJ, et al. Sleep. 2008 Sep;31(9):1310-6. Sleep. 2008. PMID: 18788656 Free PMC article. Clinical Trial.
STUDY OBJECTIVES: To assess whether premedication with eszopiclone would improve sleep duration and continuity during polysomnography, thereby improving the quality of diagnostic and CPAP titration studies. ...PATIENTS: 226 adult subjects undergoing polysomnography for sus …
STUDY OBJECTIVES: To assess whether premedication with eszopiclone would improve sleep duration and continuity during polysomnography …
The effects of eszopiclone on sleep spindles and memory consolidation in schizophrenia: a randomized placebo-controlled trial.
Wamsley EJ, Shinn AK, Tucker MA, Ono KE, McKinley SK, Ely AV, Goff DC, Stickgold R, Manoach DS. Wamsley EJ, et al. Sleep. 2013 Sep 1;36(9):1369-76. doi: 10.5665/sleep.2968. Sleep. 2013. PMID: 23997371 Free PMC article. Clinical Trial.
We investigated whether eszopiclone could increase spindles and thereby improve memory consolidation in schizophrenia. ...In the combined eszopiclone and placebo groups, spindle number and density predicted overnight MST improvement. ...
We investigated whether eszopiclone could increase spindles and thereby improve memory consolidation in schizophrenia. ...In the comb …
Eszopiclone improves insomnia and depressive and anxious symptoms in perimenopausal and postmenopausal women with hot flashes: a randomized, double-blinded, placebo-controlled crossover trial.
Joffe H, Petrillo L, Viguera A, Koukopoulos A, Silver-Heilman K, Farrell A, Yu G, Silver M, Cohen LS. Joffe H, et al. Am J Obstet Gynecol. 2010 Feb;202(2):171.e1-171.e11. doi: 10.1016/j.ajog.2009.10.868. Epub 2009 Dec 24. Am J Obstet Gynecol. 2010. PMID: 20035910 Clinical Trial.
Eszopiclone improved (P < .05) all sleep parameters, depressive symptoms, anxiety symptoms, quality of life, and nighttime but not daytime hot flashes. CONCLUSION: Eszopiclone treats insomnia and cooccurring menopause-related symptoms. ...
Eszopiclone improved (P < .05) all sleep parameters, depressive symptoms, anxiety symptoms, quality of life, and nighttime but not
Assessment of Suvorexant and Eszopiclone as Alternatives to Benzodiazepines for Treating Insomnia in Patients With Major Depressive Disorder.
Shigetsura Y, Imai S, Endo H, Shimizu Y, Ueda K, Murai T, Itohara K, Nakagawa S, Yonezawa A, Ikemi Y, Fukatsu S, Kitada N, Terada T, Nakagawa T, Matsubara K. Shigetsura Y, et al. Clin Neuropharmacol. 2022 May-Jun 01;45(3):52-60. doi: 10.1097/WNF.0000000000000499. Epub 2022 Apr 14. Clin Neuropharmacol. 2022. PMID: 35579484 Clinical Trial.
OBJECTIVES: We investigated the utility of switching from benzodiazepines to suvorexant or eszopiclone to manage benzodiazepine-unresponsive insomnia in patients with major depressive disorder (MDD) in a randomized, open-label study. ...Adverse events were recorded through …
OBJECTIVES: We investigated the utility of switching from benzodiazepines to suvorexant or eszopiclone to manage benzodiazepine-unres …
The impact of eszopiclone on sleep and cognition in patients with schizophrenia and insomnia: a double-blind, randomized, placebo-controlled trial.
Tek C, Palmese LB, Krystal AD, Srihari VH, DeGeorge PC, Reutenauer EL, Guloksuz S. Tek C, et al. Schizophr Res. 2014 Dec;160(1-3):180-5. doi: 10.1016/j.schres.2014.10.002. Epub 2014 Oct 29. Schizophr Res. 2014. PMID: 25454802 Free PMC article. Clinical Trial.
Sleep remained improved during single-blind placebo phase after eszopiclone was stopped, but the working memory improvement in patients with schizophrenia was not durable. CONCLUSIONS: Eszopiclone stands as a safe and effective alternative for the treatment of insom …
Sleep remained improved during single-blind placebo phase after eszopiclone was stopped, but the working memory improvement in patien …
Eszopiclone versus zopiclone in the treatment of insomnia.
Pinto LR Jr, Bittencourt LR, Treptow EC, Braga LR, Tufik S. Pinto LR Jr, et al. Clinics (Sao Paulo). 2016 Jan;71(1):5-9. doi: 10.6061/clinics/2016(01)02. Clinics (Sao Paulo). 2016. PMID: 26872077 Free PMC article. Clinical Trial.
RESULTS: The primary efficacy analysis demonstrated the non-inferiority of eszopiclone over zopiclone. Analysis of objective parameters assessed by polysomnography showed that eszopiclone increased total sleep time and also improved sleep efficiency. ...Adverse even …
RESULTS: The primary efficacy analysis demonstrated the non-inferiority of eszopiclone over zopiclone. Analysis of objective paramete …
Pharmacokinetics and safety of eszopiclone in healthy Chinese volunteers.
Wu F, Zhao XL, Wei MJ, Wang SM, Zhou H, Guo SJ, Zhang P. Wu F, et al. Arzneimittelforschung. 2012 Dec;62(12):561-5. doi: 10.1055/s-0032-1327570. Epub 2012 Oct 4. Arzneimittelforschung. 2012. PMID: 23038043 Clinical Trial.
In multiple-dose study, 8 subjects were given 3 mg eszopiclone once daily consecutively for 7 days. Blood samples were collected over 24 h and plasma eszopiclone were determined using a validated liquid chromatography/mass spectrometry (LC/MS/MS) assay. ...The syste …
In multiple-dose study, 8 subjects were given 3 mg eszopiclone once daily consecutively for 7 days. Blood samples were collected over …
Lemborexant for the Treatment of Insomnia: Direct and Indirect Comparisons With Other Hypnotics Using Number Needed to Treat, Number Needed to Harm, and Likelihood to Be Helped or Harmed.
Citrome L, Juday T, Frech F, Atkins N Jr. Citrome L, et al. J Clin Psychiatry. 2021 Jun 1;82:20m13795. doi: 10.4088/JCP.20m13795. J Clin Psychiatry. 2021. PMID: 34077032 Free article. Clinical Trial.
Direct comparisons were made with zolpidem extended release (ER), and indirect comparisons were made with other hypnotic agents, including suvorexant, doxepin, ramelteon, zolpidem immediate release, eszopiclone, zaleplon, and selected benzodiazepines, using data from publi …
Direct comparisons were made with zolpidem extended release (ER), and indirect comparisons were made with other hypnotic agents, including s …
60 results